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The map label for this gene is rtn [H]

Identifier: 238895736

GI number: 238895736

Start: 3668131

End: 3669693

Strand: Direct

Name: rtn [H]

Synonym: KP1_3839

Alternate gene names: 238895736

Gene position: 3668131-3669693 (Clockwise)

Preceding gene: 238895735

Following gene: 238895737

Centisome position: 69.89

GC content: 57.2

Gene sequence:

>1563_bases
ATGCTTACTCGCTACTTTTCGCCCCAGCGTAAAACCTGGTTAACCAGCCTGAGCGTGGGGATCATCGTCGCGCTGTTGGC
CGGGAGCATTCAGTTTATGGTGATCTACCATAACCGGGCCGAGCGCTTCGACGCCATTATCAACAATGTTAATACCTATC
TGAAAAGCTATTTTCACGACCTGCGCCAGACCATTGACGGCCTGCAGCCGCTGGTGGACCAGCCCTGCGAGAATATTGAC
TCCGGGCTTACCTCCCACGCCGCGTTCAGCCCCAACGTCCGCGCTTTCCTGCTGGTCAAAAACGGCATCGCCTTTTGCTC
ATCGGCCACGGGAGCCATGAATACGCCCCTCAGCCAGCTGATCCCGGCCATCGATATCAGCAAACCCGTTGCTATGGCGA
TTTTACCAGGCACGCCGATGATGCCGAAGAGCGCGGCGCTGGCGCTGTGGGTAGGTAAACCCGGCGATCAAAACAGCGGC
ATTTTCGTGTCGATTAACGCTAATCTCACACCGTATATCCTCTATTCCGCACGGCAAAACGATTTCAGCGGCATTGCGCT
GGCCATCGATCACACCGCTATCTCCACCTTCAGTAATCGGCTGGTGGATCCGCAAACGCTGCATAACGCGCCGATCCGCC
AGGCACAGATCGAGGGCTTACCGCTGAAGGTCTACCTGTATGCCAACAGCTGGCTGGCGGAAAATACGCAGTTTGCTCTG
CTGCTCGGGGTCGTCTGCGGCCTGCTGGCGGGGCTGCTCTGCTATTACGTGCTGACGATCAAATCGGATCCGCGAAAATC
CATTCTGCTGGGGATCAAAAATAACCAGTTCTACATCGTTTATCAGCCGGTGGTTAATGCTCAGACTCTACGTATCAGCG
GCGTGGAGGTCCTAATGCGCTGGCGCCATCCGGTGGTTGGTGAAATTCCGCCCGACGTTTTTATTAACCTGGCCGAAACC
CAGCAGATGATCGTGCCGCTAACCCATCACCTGCTCGCGCTGATCGCCAGCGACGCTGCGGTGTTGAAGCGTATTCTGCC
GCGCGGCGTGAAGCTGGGGCTGAATATTTCCCCTGCCCATCTGCAGGCCGACAGCTTCCGCGACGATATGCTGCGCTTCG
CCGCCGCGCTGCCAGCCGACCACTTTCACGTGGTGCTGGAGGTAACCGAGCGGGCGATGATTGATAAAGAAAAATCGATG
GCTAACTTCGCCTGGCTCCACCGCCAGGGATTCGAAATCGCGATTGATGATTTCGGCACCGGGCATAGCGCGCTGATCTA
TCTCGAACGCTATAACTTCGATTATCTGAAGATCGATCGCGGTTTTGTGCAGGCGATTGGTACTGAAACAGTAACCTCGC
CGGTGCTGGATGCGGTACTGACCCTCAGCCGCCGGCTGAAATTAATGACCGTCGCCGAAGGGGTGGAGACCCAGGAACAG
GCGGAGTGGCTTCGCGGCCAGGGCGTTCATTTCCTGCAGGGGTACTGGATCAGCCGACCGCTGTCGCTGGCCGGGCTGGT
GGCTGCGCACGATGAACCCGCGAACTATTTCACAACGCGCTAA

Upstream 100 bases:

>100_bases
CTCAACGTCGCAAAATAAGCTATGTCTTTTAAGTGGGAATGAGAAAAACGACGACCGACACTCCGTTGATGCGCTTCAAT
AATACGGAAAGAATCTGGCT

Downstream 100 bases:

>100_bases
GTCTCACTTATGATGCGGGAACGGATGTCGGCCATGGGGGCCGGCCATGACAGGGTATTCTGCCGCCTATGTATGCGCGC
CTCTTTCTGATTCTGCTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MLTRYFSPQRKTWLTSLSVGIIVALLAGSIQFMVIYHNRAERFDAIINNVNTYLKSYFHDLRQTIDGLQPLVDQPCENID
SGLTSHAAFSPNVRAFLLVKNGIAFCSSATGAMNTPLSQLIPAIDISKPVAMAILPGTPMMPKSAALALWVGKPGDQNSG
IFVSINANLTPYILYSARQNDFSGIALAIDHTAISTFSNRLVDPQTLHNAPIRQAQIEGLPLKVYLYANSWLAENTQFAL
LLGVVCGLLAGLLCYYVLTIKSDPRKSILLGIKNNQFYIVYQPVVNAQTLRISGVEVLMRWRHPVVGEIPPDVFINLAET
QQMIVPLTHHLLALIASDAAVLKRILPRGVKLGLNISPAHLQADSFRDDMLRFAAALPADHFHVVLEVTERAMIDKEKSM
ANFAWLHRQGFEIAIDDFGTGHSALIYLERYNFDYLKIDRGFVQAIGTETVTSPVLDAVLTLSRRLKLMTVAEGVETQEQ
AEWLRGQGVHFLQGYWISRPLSLAGLVAAHDEPANYFTTR

Sequences:

>Translated_520_residues
MLTRYFSPQRKTWLTSLSVGIIVALLAGSIQFMVIYHNRAERFDAIINNVNTYLKSYFHDLRQTIDGLQPLVDQPCENID
SGLTSHAAFSPNVRAFLLVKNGIAFCSSATGAMNTPLSQLIPAIDISKPVAMAILPGTPMMPKSAALALWVGKPGDQNSG
IFVSINANLTPYILYSARQNDFSGIALAIDHTAISTFSNRLVDPQTLHNAPIRQAQIEGLPLKVYLYANSWLAENTQFAL
LLGVVCGLLAGLLCYYVLTIKSDPRKSILLGIKNNQFYIVYQPVVNAQTLRISGVEVLMRWRHPVVGEIPPDVFINLAET
QQMIVPLTHHLLALIASDAAVLKRILPRGVKLGLNISPAHLQADSFRDDMLRFAAALPADHFHVVLEVTERAMIDKEKSM
ANFAWLHRQGFEIAIDDFGTGHSALIYLERYNFDYLKIDRGFVQAIGTETVTSPVLDAVLTLSRRLKLMTVAEGVETQEQ
AEWLRGQGVHFLQGYWISRPLSLAGLVAAHDEPANYFTTR
>Mature_520_residues
MLTRYFSPQRKTWLTSLSVGIIVALLAGSIQFMVIYHNRAERFDAIINNVNTYLKSYFHDLRQTIDGLQPLVDQPCENID
SGLTSHAAFSPNVRAFLLVKNGIAFCSSATGAMNTPLSQLIPAIDISKPVAMAILPGTPMMPKSAALALWVGKPGDQNSG
IFVSINANLTPYILYSARQNDFSGIALAIDHTAISTFSNRLVDPQTLHNAPIRQAQIEGLPLKVYLYANSWLAENTQFAL
LLGVVCGLLAGLLCYYVLTIKSDPRKSILLGIKNNQFYIVYQPVVNAQTLRISGVEVLMRWRHPVVGEIPPDVFINLAET
QQMIVPLTHHLLALIASDAAVLKRILPRGVKLGLNISPAHLQADSFRDDMLRFAAALPADHFHVVLEVTERAMIDKEKSM
ANFAWLHRQGFEIAIDDFGTGHSALIYLERYNFDYLKIDRGFVQAIGTETVTSPVLDAVLTLSRRLKLMTVAEGVETQEQ
AEWLRGQGVHFLQGYWISRPLSLAGLVAAHDEPANYFTTR

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=504, Percent_Identity=55.3571428571429, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI87081980, Length=519, Percent_Identity=31.0211946050096, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI87081845, Length=269, Percent_Identity=37.9182156133829, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786507, Length=237, Percent_Identity=40.9282700421941, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI87081743, Length=265, Percent_Identity=33.9622641509434, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1790496, Length=239, Percent_Identity=31.7991631799163, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI87081921, Length=232, Percent_Identity=33.6206896551724, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787541, Length=234, Percent_Identity=28.2051282051282, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI226510982, Length=252, Percent_Identity=32.5396825396825, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI87082096, Length=158, Percent_Identity=38.6075949367089, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788849, Length=235, Percent_Identity=26.3829787234043, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787055, Length=238, Percent_Identity=29.8319327731092, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 57621; Mature: 57621

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRYFSPQRKTWLTSLSVGIIVALLAGSIQFMVIYHNRAERFDAIINNVNTYLKSYFHD
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
LRQTIDGLQPLVDQPCENIDSGLTSHAAFSPNVRAFLLVKNGIAFCSSATGAMNTPLSQL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCHHHH
IPAIDISKPVAMAILPGTPMMPKSAALALWVGKPGDQNSGIFVSINANLTPYILYSARQN
CCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCC
DFSGIALAIDHTAISTFSNRLVDPQTLHNAPIRQAQIEGLPLKVYLYANSWLAENTQFAL
CCCCEEEEEEHHHHHHHHHCCCCCHHHCCCCCCHHEECCCCEEEEEEECCEECCCCHHHH
LLGVVCGLLAGLLCYYVLTIKSDPRKSILLGIKNNQFYIVYQPVVNAQTLRISGVEVLMR
HHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCEEEEEEECCCCCEEEEECHHHHHHH
WRHPVVGEIPPDVFINLAETQQMIVPLTHHLLALIASDAAVLKRILPRGVKLGLNISPAH
HCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEECCCCCHHH
LQADSFRDDMLRFAAALPADHFHVVLEVTERAMIDKEKSMANFAWLHRQGFEIAIDDFGT
CCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERYNFDYLKIDRGFVQAIGTETVTSPVLDAVLTLSRRLKLMTVAEGVETQEQ
CCEEEEEEEECCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHH
AEWLRGQGVHFLQGYWISRPLSLAGLVAAHDEPANYFTTR
HHHHHCCCCCEECCCHHCCCHHHHEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLTRYFSPQRKTWLTSLSVGIIVALLAGSIQFMVIYHNRAERFDAIINNVNTYLKSYFHD
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
LRQTIDGLQPLVDQPCENIDSGLTSHAAFSPNVRAFLLVKNGIAFCSSATGAMNTPLSQL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCHHHH
IPAIDISKPVAMAILPGTPMMPKSAALALWVGKPGDQNSGIFVSINANLTPYILYSARQN
CCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCC
DFSGIALAIDHTAISTFSNRLVDPQTLHNAPIRQAQIEGLPLKVYLYANSWLAENTQFAL
CCCCEEEEEEHHHHHHHHHCCCCCHHHCCCCCCHHEECCCCEEEEEEECCEECCCCHHHH
LLGVVCGLLAGLLCYYVLTIKSDPRKSILLGIKNNQFYIVYQPVVNAQTLRISGVEVLMR
HHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCEEEEEEECCCCCEEEEECHHHHHHH
WRHPVVGEIPPDVFINLAETQQMIVPLTHHLLALIASDAAVLKRILPRGVKLGLNISPAH
HCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEECCCCCHHH
LQADSFRDDMLRFAAALPADHFHVVLEVTERAMIDKEKSMANFAWLHRQGFEIAIDDFGT
CCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERYNFDYLKIDRGFVQAIGTETVTSPVLDAVLTLSRRLKLMTVAEGVETQEQ
CCEEEEEEEECCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHH
AEWLRGQGVHFLQGYWISRPLSLAGLVAAHDEPANYFTTR
HHHHHCCCCCEECCCHHCCCHHHHEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]