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The map label for this gene is yeiG [H]

Identifier: 238895718

GI number: 238895718

Start: 3647668

End: 3648501

Strand: Direct

Name: yeiG [H]

Synonym: KP1_3819

Alternate gene names: 238895718

Gene position: 3647668-3648501 (Clockwise)

Preceding gene: 238895711

Following gene: 238895722

Centisome position: 69.5

GC content: 62.59

Gene sequence:

>834_bases
ATGGAACTGCTTGAAGAGCATCGCTGTTTTGACGGCCAGCAACAACGCTGGCGTCATCACTCCCCTGTCCTGAACTGCGC
CATGACGTTCAGCATTTTTTTACCCCCTGAGCGCGAAACGCCGCCGCCGGTGCTGTACTGGCTGTCGGGGCTGACCTGTA
ACGATGAGAACTTTACCACCAAGGCGGGCGCCCAGCGCATTGCCGCCGAGCTGGGCATCGCGCTGGTGATGCCGGATACC
AGCCCGCGCGGTGACGAGGCGGCCAACGACGAAGGTTACGATCTCGGACAAGGCGCCGGCTTCTACCTGAACGCCACCGA
GGCGCCCTGGGCGGCGCACTACCGAATGTACGATTACCTGCGTGACGAACTGCCCGCGCTTATTCGTAGCGAGTTTAGCG
TGGGCGAACGCTGCGCCGTCAGCGGCCACTCGATGGGCGGCCACGGCGCGCTCATCATGGCGCTCAAAAATCCCGGCCGC
TACGCCAGCGTCTCCGCCTTCGCGCCGATAGTCAATCCCTCCCAGGTCCCGTGGGGCAAGAAAGCGTTTACCGCCTATCT
CGGCGCGGATGAATCGGCATGGCACTCCTGGGACAGCTGCGCGCTGATGCAGGCCAGCCGGCCGGAGGACGCCGTGCCGA
CGCTTATCGATCAGGGCGACAACGATCCTTTCCTTGCCGGACAGTTGCAGCCGGCGGTACTGGCGGAGGTCGCGCGGCAG
AAGGCCTGGCCGTTAACGCTGCGCATCCAGCCCGGTTACGACCACAGCTATTACTTTATTGCCTCGTTTATTGAAGACCA
TCTGCGCTTCCATGCGCAGCATCTCTTTGGCTAA

Upstream 100 bases:

>100_bases
GCAGTAAGTTCTCAAAAGGAGAAAGTGAAAGTTGCTCACCGGCTAATGAAATATCTGTATTATGAACGTTTACGCGCACA
TCCCTTCCGAGGAGCCTTGC

Downstream 100 bases:

>100_bases
ACGCCAATGCGCCGCGAAGCTGCTTCGCGGCGCATGTTCAGGCCTACAGGACGCGTTTTAGCGCCGGCAATCAGAAGCGA
TAATCCACCGCCATAAAGTA

Product: putative esterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MELLEEHRCFDGQQQRWRHHSPVLNCAMTFSIFLPPERETPPPVLYWLSGLTCNDENFTTKAGAQRIAAELGIALVMPDT
SPRGDEAANDEGYDLGQGAGFYLNATEAPWAAHYRMYDYLRDELPALIRSEFSVGERCAVSGHSMGGHGALIMALKNPGR
YASVSAFAPIVNPSQVPWGKKAFTAYLGADESAWHSWDSCALMQASRPEDAVPTLIDQGDNDPFLAGQLQPAVLAEVARQ
KAWPLTLRIQPGYDHSYYFIASFIEDHLRFHAQHLFG

Sequences:

>Translated_277_residues
MELLEEHRCFDGQQQRWRHHSPVLNCAMTFSIFLPPERETPPPVLYWLSGLTCNDENFTTKAGAQRIAAELGIALVMPDT
SPRGDEAANDEGYDLGQGAGFYLNATEAPWAAHYRMYDYLRDELPALIRSEFSVGERCAVSGHSMGGHGALIMALKNPGR
YASVSAFAPIVNPSQVPWGKKAFTAYLGADESAWHSWDSCALMQASRPEDAVPTLIDQGDNDPFLAGQLQPAVLAEVARQ
KAWPLTLRIQPGYDHSYYFIASFIEDHLRFHAQHLFG
>Mature_277_residues
MELLEEHRCFDGQQQRWRHHSPVLNCAMTFSIFLPPERETPPPVLYWLSGLTCNDENFTTKAGAQRIAAELGIALVMPDT
SPRGDEAANDEGYDLGQGAGFYLNATEAPWAAHYRMYDYLRDELPALIRSEFSVGERCAVSGHSMGGHGALIMALKNPGR
YASVSAFAPIVNPSQVPWGKKAFTAYLGADESAWHSWDSCALMQASRPEDAVPTLIDQGDNDPFLAGQLQPAVLAEVARQ
KAWPLTLRIQPGYDHSYYFIASFIEDHLRFHAQHLFG

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=279, Percent_Identity=52.3297491039427, Blast_Score=303, Evalue=1e-82,
Organism=Escherichia coli, GI1788477, Length=277, Percent_Identity=81.5884476534296, Blast_Score=470, Evalue=1e-134,
Organism=Escherichia coli, GI1786551, Length=276, Percent_Identity=51.8115942028985, Blast_Score=304, Evalue=3e-84,
Organism=Caenorhabditis elegans, GI17510185, Length=282, Percent_Identity=44.3262411347518, Blast_Score=237, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6322393, Length=296, Percent_Identity=43.9189189189189, Blast_Score=244, Evalue=9e-66,
Organism=Drosophila melanogaster, GI45551932, Length=284, Percent_Identity=49.6478873239437, Blast_Score=265, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24648347, Length=284, Percent_Identity=49.6478873239437, Blast_Score=265, Evalue=4e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 30784; Mature: 30784

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLEEHRCFDGQQQRWRHHSPVLNCAMTFSIFLPPERETPPPVLYWLSGLTCNDENFTT
CCCHHHHCCCCCHHHHHHHCCHHHEEEEEEEEEECCCCCCCCCEEEEECCEEECCCCCCH
KAGAQRIAAELGIALVMPDTSPRGDEAANDEGYDLGQGAGFYLNATEAPWAAHYRMYDYL
HHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
RDELPALIRSEFSVGERCAVSGHSMGGHGALIMALKNPGRYASVSAFAPIVNPSQVPWGK
HHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCCEEEHHHHCCCCCCCCCCCCH
KAFTAYLGADESAWHSWDSCALMQASRPEDAVPTLIDQGDNDPFLAGQLQPAVLAEVARQ
HHHEEEECCCCHHHCCCCCEEEEECCCCCCCCCHHHHCCCCCCEEECCCCHHHHHHHHHH
KAWPLTLRIQPGYDHSYYFIASFIEDHLRFHAQHLFG
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELLEEHRCFDGQQQRWRHHSPVLNCAMTFSIFLPPERETPPPVLYWLSGLTCNDENFTT
CCCHHHHCCCCCHHHHHHHCCHHHEEEEEEEEEECCCCCCCCCEEEEECCEEECCCCCCH
KAGAQRIAAELGIALVMPDTSPRGDEAANDEGYDLGQGAGFYLNATEAPWAAHYRMYDYL
HHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
RDELPALIRSEFSVGERCAVSGHSMGGHGALIMALKNPGRYASVSAFAPIVNPSQVPWGK
HHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCCEEEHHHHCCCCCCCCCCCCH
KAFTAYLGADESAWHSWDSCALMQASRPEDAVPTLIDQGDNDPFLAGQLQPAVLAEVARQ
HHHEEEECCCCHHHCCCCCEEEEECCCCCCCCCHHHHCCCCCCEEECCCCHHHHHHHHHH
KAWPLTLRIQPGYDHSYYFIASFIEDHLRFHAQHLFG
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA