| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is rbtD [H]
Identifier: 238895667
GI number: 238895667
Start: 3589218
End: 3589946
Strand: Direct
Name: rbtD [H]
Synonym: KP1_3763
Alternate gene names: 238895667
Gene position: 3589218-3589946 (Clockwise)
Preceding gene: 238895665
Following gene: 238895668
Centisome position: 68.39
GC content: 62.0
Gene sequence:
>729_bases ATGAATACTTCCCTCAGCGGTAAAGTCGCCGCGATCACCGGCGCGGCGTCCGGTATCGGCCTCGAGTGCGCGAGGACCCT GCTGGGGGCTGGCGCAAAAGTGGTACTGATCGACCGCGAAGGCGAAAAGCTCAACAAACTGGTCGCCGAACTTGGCGAAA ACGCCTTCGCCCTGCAGGTCGACCTGATGCAGGCGGACCAGGTCGATAACCTACTGCAGGGCATTTTGCAGCTTACCGGG CGTCTCGATATCTTCCACGCCAACGCCGGCGCCTATATCGGCGGGCCGGTGGCCGAGGGCGACCCGGACGTCTGGGACCG CGTGCTGCACCTTAATATCAACGCCGCCTTCCGCTGCGTGCGCAGCGTCCTGCCGCATCTGATCGCGCAAAAATCCGGGG ATATTATCTTCACCAGCTCGATCGCGGGCGTGGTGCCGGTGATCTGGGAGCCTGTCTATACCGCGTCGAAATTCGCGGTG CAGGCATTTGTACACACCACTCGTCGCCAGGTGGCGCAGTATGGCGTGCGCGTCGGCGCCGTACTGCCGGGCCCGGTGGT TACCGCTCTGCTGGACGACTGGCCAAAAGCCAAAATGGACGAAGCGCTGGCCAACGGCAGCCTGATGCAGCCGATTGAAG TGGCGGAGTCGGTGCTGTTTATGGTGACGCGTTCGAAAAACGTCACCGTGCGCGACATTGTGATCCTGCCGAACAGCGTG GATCTCTGA
Upstream 100 bases:
>100_bases TACCAGGTTTAGTCTATCACCTCGAACGTGATGCCCTCGCGTTCGATAGTTTTAACCAGACACGGCAAAGGATTATAAAA TGAACCACTCTGTCTCCTCT
Downstream 100 bases:
>100_bases CCCTGGCCAGCCTGTGAGAGGATGTGATGCAAAACGATACGCAAAACATTATTGGCGTGGATGTCGGTTCAGGCAGCGTG CGCGCCGGGGTATTCAATCT
Product: putative ribitol dehydrogenase
Products: NA
Alternate protein names: RDH [H]
Number of amino acids: Translated: 242; Mature: 242
Protein sequence:
>242_residues MNTSLSGKVAAITGAASGIGLECARTLLGAGAKVVLIDREGEKLNKLVAELGENAFALQVDLMQADQVDNLLQGILQLTG RLDIFHANAGAYIGGPVAEGDPDVWDRVLHLNINAAFRCVRSVLPHLIAQKSGDIIFTSSIAGVVPVIWEPVYTASKFAV QAFVHTTRRQVAQYGVRVGAVLPGPVVTALLDDWPKAKMDEALANGSLMQPIEVAESVLFMVTRSKNVTVRDIVILPNSV DL
Sequences:
>Translated_242_residues MNTSLSGKVAAITGAASGIGLECARTLLGAGAKVVLIDREGEKLNKLVAELGENAFALQVDLMQADQVDNLLQGILQLTG RLDIFHANAGAYIGGPVAEGDPDVWDRVLHLNINAAFRCVRSVLPHLIAQKSGDIIFTSSIAGVVPVIWEPVYTASKFAV QAFVHTTRRQVAQYGVRVGAVLPGPVVTALLDDWPKAKMDEALANGSLMQPIEVAESVLFMVTRSKNVTVRDIVILPNSV DL >Mature_242_residues MNTSLSGKVAAITGAASGIGLECARTLLGAGAKVVLIDREGEKLNKLVAELGENAFALQVDLMQADQVDNLLQGILQLTG RLDIFHANAGAYIGGPVAEGDPDVWDRVLHLNINAAFRCVRSVLPHLIAQKSGDIIFTSSIAGVVPVIWEPVYTASKFAV QAFVHTTRRQVAQYGVRVGAVLPGPVVTALLDDWPKAKMDEALANGSLMQPIEVAESVLFMVTRSKNVTVRDIVILPNSV DL
Specific function: Unknown
COG id: COG4221
COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI20149619, Length=246, Percent_Identity=32.9268292682927, Blast_Score=113, Evalue=1e-25, Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=30.9644670050761, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=32.843137254902, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI157739938, Length=243, Percent_Identity=27.1604938271605, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=26.1410788381743, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI40254992, Length=215, Percent_Identity=26.046511627907, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=33.5106382978723, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI5031737, Length=189, Percent_Identity=29.1005291005291, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=29.1005291005291, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI15277342, Length=239, Percent_Identity=28.0334728033473, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=32.9411764705882, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=26.1224489795918, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI66933014, Length=207, Percent_Identity=31.4009661835749, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI7705855, Length=192, Percent_Identity=31.25, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI59889578, Length=224, Percent_Identity=26.7857142857143, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=24.2290748898678, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI142976729, Length=244, Percent_Identity=25.4098360655738, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI4758504, Length=206, Percent_Identity=30.0970873786408, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI19923817, Length=238, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=27.0718232044199, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI223718074, Length=194, Percent_Identity=28.3505154639175, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI87082100, Length=233, Percent_Identity=30.9012875536481, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1787820, Length=234, Percent_Identity=27.7777777777778, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1787335, Length=223, Percent_Identity=26.9058295964126, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1787526, Length=194, Percent_Identity=32.4742268041237, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI1786812, Length=246, Percent_Identity=28.0487804878049, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1789208, Length=187, Percent_Identity=33.1550802139037, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI87082160, Length=187, Percent_Identity=27.807486631016, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1787905, Length=230, Percent_Identity=30, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1786701, Length=210, Percent_Identity=27.6190476190476, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1788459, Length=237, Percent_Identity=27.0042194092827, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1790717, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1789378, Length=242, Percent_Identity=26.4462809917355, Blast_Score=69, Evalue=3e-13, Organism=Caenorhabditis elegans, GI193204405, Length=244, Percent_Identity=31.9672131147541, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562910, Length=249, Percent_Identity=30.1204819277108, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562908, Length=249, Percent_Identity=30.1204819277108, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562906, Length=247, Percent_Identity=31.1740890688259, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI71994604, Length=241, Percent_Identity=29.4605809128631, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17560332, Length=249, Percent_Identity=30.5220883534137, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560676, Length=229, Percent_Identity=30.1310043668122, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17531453, Length=245, Percent_Identity=29.7959183673469, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI71994600, Length=238, Percent_Identity=30.2521008403361, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17559104, Length=247, Percent_Identity=30.3643724696356, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17544670, Length=247, Percent_Identity=30.7692307692308, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17560150, Length=242, Percent_Identity=28.099173553719, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560220, Length=246, Percent_Identity=28.8617886178862, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI72000259, Length=244, Percent_Identity=27.0491803278689, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17562904, Length=248, Percent_Identity=28.6290322580645, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562990, Length=241, Percent_Identity=27.8008298755187, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17551412, Length=252, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17538480, Length=248, Percent_Identity=27.4193548387097, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI25147288, Length=230, Percent_Identity=26.9565217391304, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17563726, Length=249, Percent_Identity=26.9076305220884, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=25.0996015936255, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17555706, Length=232, Percent_Identity=25.4310344827586, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17538486, Length=246, Percent_Identity=27.6422764227642, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17564282, Length=194, Percent_Identity=26.2886597938144, Blast_Score=68, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17555612, Length=237, Percent_Identity=27.8481012658228, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17565030, Length=250, Percent_Identity=27.6, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=26.0416666666667, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI193203117, Length=200, Percent_Identity=27, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17508895, Length=248, Percent_Identity=24.5967741935484, Blast_Score=64, Evalue=9e-11, Organism=Caenorhabditis elegans, GI193203115, Length=204, Percent_Identity=25.9803921568627, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=251, Percent_Identity=30.6772908366534, Blast_Score=91, Evalue=1e-19, Organism=Saccharomyces cerevisiae, GI6322067, Length=196, Percent_Identity=27.5510204081633, Blast_Score=77, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=30.6122448979592, Blast_Score=70, Evalue=4e-13, Organism=Drosophila melanogaster, GI21358495, Length=247, Percent_Identity=29.1497975708502, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI21355319, Length=233, Percent_Identity=29.6137339055794, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI28571387, Length=241, Percent_Identity=29.4605809128631, Blast_Score=94, Evalue=6e-20, Organism=Drosophila melanogaster, GI23397609, Length=238, Percent_Identity=31.9327731092437, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24639444, Length=226, Percent_Identity=30.9734513274336, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI28571526, Length=203, Percent_Identity=32.0197044334975, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI24663911, Length=245, Percent_Identity=29.7959183673469, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI21357041, Length=223, Percent_Identity=30.9417040358744, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI24580925, Length=202, Percent_Identity=30.6930693069307, Blast_Score=85, Evalue=3e-17, Organism=Drosophila melanogaster, GI24641232, Length=246, Percent_Identity=29.6747967479675, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI24644339, Length=233, Percent_Identity=30.4721030042918, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI281364494, Length=248, Percent_Identity=27.0161290322581, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=30.6122448979592, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI281364892, Length=226, Percent_Identity=28.7610619469027, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24643142, Length=220, Percent_Identity=32.7272727272727, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24648944, Length=244, Percent_Identity=29.0983606557377, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI116007236, Length=246, Percent_Identity=26.0162601626016, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24665243, Length=199, Percent_Identity=28.643216080402, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=28.3582089552239, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=26.9005847953216, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24640492, Length=202, Percent_Identity=26.2376237623762, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24584744, Length=195, Percent_Identity=29.7435897435897, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24665247, Length=200, Percent_Identity=29, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI221331216, Length=200, Percent_Identity=29, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI116007238, Length=196, Percent_Identity=26.0204081632653, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI17737361, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24641388, Length=247, Percent_Identity=26.7206477732794, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=26.4550264550265, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI21356301, Length=227, Percent_Identity=26.431718061674, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24584748, Length=201, Percent_Identity=27.363184079602, Blast_Score=64, Evalue=6e-11, Organism=Drosophila melanogaster, GI161076933, Length=201, Percent_Identity=27.363184079602, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.56 [H]
Molecular weight: Translated: 25761; Mature: 25761
Theoretical pI: Translated: 5.66; Mature: 5.66
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNTSLSGKVAAITGAASGIGLECARTLLGAGAKVVLIDREGEKLNKLVAELGENAFALQV CCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE DLMQADQVDNLLQGILQLTGRLDIFHANAGAYIGGPVAEGDPDVWDRVLHLNINAAFRCV EHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEECCCCCCCCHHHHHHEEEECHHHHHHHH RSVLPHLIAQKSGDIIFTSSIAGVVPVIWEPVYTASKFAVQAFVHTTRRQVAQYGVRVGA HHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEECC VLPGPVVTALLDDWPKAKMDEALANGSLMQPIEVAESVLFMVTRSKNVTVRDIVILPNSV CCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCEEEEEEEECCCC DL CC >Mature Secondary Structure MNTSLSGKVAAITGAASGIGLECARTLLGAGAKVVLIDREGEKLNKLVAELGENAFALQV CCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE DLMQADQVDNLLQGILQLTGRLDIFHANAGAYIGGPVAEGDPDVWDRVLHLNINAAFRCV EHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEECCCCCCCCHHHHHHEEEECHHHHHHHH RSVLPHLIAQKSGDIIFTSSIAGVVPVIWEPVYTASKFAVQAFVHTTRRQVAQYGVRVGA HHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEECC VLPGPVVTALLDDWPKAKMDEALANGSLMQPIEVAESVLFMVTRSKNVTVRDIVILPNSV CCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCEEEEEEEECCCC DL CC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 3904726; 2933028; 3891331 [H]