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The map label for this gene is yycG [H]

Identifier: 238895641

GI number: 238895641

Start: 3555400

End: 3557343

Strand: Direct

Name: yycG [H]

Synonym: KP1_3735

Alternate gene names: 238895641

Gene position: 3555400-3557343 (Clockwise)

Preceding gene: 238895640

Following gene: 238895642

Centisome position: 67.74

GC content: 62.91

Gene sequence:

>1944_bases
TTGAAAAGGGTGTCTGCGATCTTCGCGGCGGTCCGGCGTTGCCGGCCGCGGCTCCTGGCAGGCTGGCTGCTCAGCTGTGG
ATTACTCTTGCTGCTGGTCGCCCCGCAGGCGCAGGCGGCGACGCGCCAGGTGGGGATTGATATTCCGGTCCAGTGGTACG
CCGACGACAGCGGCCAGATGACCCTCGATCGCTTTGCCGCCCTGCCCGCAGACCAGCTCGCCACCACCCGGCAGATCCCC
TCCTTTGGTTATTCGCGAAAAACCTGGTGGCTGCGCAGCGAGCTGCCGGGCACGTGGTTTGCCGGGGAGCCGCGTTGGCT
GCAGCTGGGCCCCACTTTCGTCGACCATCTGACCATTTACTACCGGCCACTGGGCAGCGATGGCCCGTGGACGCAGCGCA
TCTTTGGCGATCGCGACGGCGCCCGCGGAAGCGATCTGCATTATCGGGAAAGGGTGCTGATACTGCCCCCTCCGCCAACC
GACGCCGGCTATGAGCTGGTCTTTCGCCTGCAGAGCACCAGCACCCTGATCCTGCTGGCCTCGCTCTCCTCTGCGCAGGC
GTTTGTGCAGCGGGCCACCGCTGACACCGCTTTCTGGAGCTTCTACTTCGGCCTGGCCGCTGTGGCCAGCGGTGTGGCGC
TTTGGCTGGCGCTGGCCCTGCGCCGGCGTCTGCTATGGGGGATCTGTCTTTTCTCGCTCAATTATCCGCTGGTGGCCGCT
CTGCACGGCTTCCCGGAGTGGTTCTTCGGCCACGCCGCGCTGCCCTTCCAGGATTTTATGATCAGTAGCCTCTCGCTGTT
CAGCTATGCCACCGCCCTCTGGCTGCACAGCGAGATTTTTGATCTGAAGAAGAATATGCCGCGACTTCATCAGCTGCTGA
TTGCCGCCGTGATACTCAACCTGGTGCTGCAGGTCAGTATTCCGCTCGGGTTTTACGGCTTCGCGATGCAGATTGAAGGG
GTAGTATTCATCATTATCACCCCGGTGCTGCTGTTCACCTCCTGGTGGCTGTGGCGCAAAAAAGCTATCGACCGTACCAC
CCTGCTGCTGGGTCTGCTGCCGCCGTTCTATGTCGCCGCCGCGGTGCTGGTGCAGTTGTCGATCCATGGGATTATCCCGT
TCCATATGGCGATCTATTCCCTCTGGCAGTACGCGCTGATCGTCCACATCATTACGGTGCTGATCATTGCCATTCTGCGG
GTGCGTGCTGAAAACCGCCAGCTGGAGCAGAAGCAGCGCCTGGCGCGCGAACTGCAGATTGAGCGTGAAGCCAGCTTCCA
CCAGCGGCAGTTTATGGGCATGGTGGCGCACGAATTCCGCACCCCGCTGGCGGTGATCCAGGCGGCGCTGGAGAATCTTC
GCCTCTCGGCGGCCTCGACCAGCCAGGAGGCGCGCTTCGATCGCATTGGCCGCGCCGCCACCCGCCTGGTGCAGCTCACC
GATAACTGCCTTGCCGACGCCCGGCTCGCCTCCCACGATCTGCACGTCGAGCGCCAGCAGACCGCCCTGCTGACGGTGAT
CAACATGGCCGCCTCGGTGGTGGCCATCTCCCATGATCACTACCTAAACATCCGCCAGCACGGCGCGGTGGAAAGCCCGC
AGCTGCAGGCCGATGCCGGCCTGCTGTGCATCGCCATCGCTAATCTGCTGGATAACGCCGTCAAGTATTCGCCCCCCGGT
GAAATCGCCATCGATATTCATTCCGATGCCGGGCAAACGGAGCTACGCATTCGCGACCACGGCCCGGGACTCCCTGCCGG
ACAGGCGGAACTGATCTTTGAGCGCTACCGCCGCGGCGAGCACACATCGCCGGTGCCAGGCGGCACTGGTCTCGGACTGT
ATGTTGCGCGTCAGATAGTGCAGGCTCATGATGGCAAACTGTGGCTGGCCGAGCATGGCCCGGACGGCTGCACCTTTATT
CTCACCCTCCCCACTGTTACTTAA

Upstream 100 bases:

>100_bases
GACAGGCCTGTCCACTCTCCCCCGCTTCCGGGGGCGTATTATCCATACCGTAGCCAGACGTCTGCGGTCAGTAATCTTTG
CATGCCGCAAGGGGGCGTGA

Downstream 100 bases:

>100_bases
GAGGAGAACGACGTATGGCTTTACGGCTGGCGATAATTGAAGATAACGCCGATCTGCTGGATGAACTGCTGGCCTGGCTG
GGCTATCGCGGCTTCGAGGT

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MKRVSAIFAAVRRCRPRLLAGWLLSCGLLLLLVAPQAQAATRQVGIDIPVQWYADDSGQMTLDRFAALPADQLATTRQIP
SFGYSRKTWWLRSELPGTWFAGEPRWLQLGPTFVDHLTIYYRPLGSDGPWTQRIFGDRDGARGSDLHYRERVLILPPPPT
DAGYELVFRLQSTSTLILLASLSSAQAFVQRATADTAFWSFYFGLAAVASGVALWLALALRRRLLWGICLFSLNYPLVAA
LHGFPEWFFGHAALPFQDFMISSLSLFSYATALWLHSEIFDLKKNMPRLHQLLIAAVILNLVLQVSIPLGFYGFAMQIEG
VVFIIITPVLLFTSWWLWRKKAIDRTTLLLGLLPPFYVAAAVLVQLSIHGIIPFHMAIYSLWQYALIVHIITVLIIAILR
VRAENRQLEQKQRLARELQIEREASFHQRQFMGMVAHEFRTPLAVIQAALENLRLSAASTSQEARFDRIGRAATRLVQLT
DNCLADARLASHDLHVERQQTALLTVINMAASVVAISHDHYLNIRQHGAVESPQLQADAGLLCIAIANLLDNAVKYSPPG
EIAIDIHSDAGQTELRIRDHGPGLPAGQAELIFERYRRGEHTSPVPGGTGLGLYVARQIVQAHDGKLWLAEHGPDGCTFI
LTLPTVT

Sequences:

>Translated_647_residues
MKRVSAIFAAVRRCRPRLLAGWLLSCGLLLLLVAPQAQAATRQVGIDIPVQWYADDSGQMTLDRFAALPADQLATTRQIP
SFGYSRKTWWLRSELPGTWFAGEPRWLQLGPTFVDHLTIYYRPLGSDGPWTQRIFGDRDGARGSDLHYRERVLILPPPPT
DAGYELVFRLQSTSTLILLASLSSAQAFVQRATADTAFWSFYFGLAAVASGVALWLALALRRRLLWGICLFSLNYPLVAA
LHGFPEWFFGHAALPFQDFMISSLSLFSYATALWLHSEIFDLKKNMPRLHQLLIAAVILNLVLQVSIPLGFYGFAMQIEG
VVFIIITPVLLFTSWWLWRKKAIDRTTLLLGLLPPFYVAAAVLVQLSIHGIIPFHMAIYSLWQYALIVHIITVLIIAILR
VRAENRQLEQKQRLARELQIEREASFHQRQFMGMVAHEFRTPLAVIQAALENLRLSAASTSQEARFDRIGRAATRLVQLT
DNCLADARLASHDLHVERQQTALLTVINMAASVVAISHDHYLNIRQHGAVESPQLQADAGLLCIAIANLLDNAVKYSPPG
EIAIDIHSDAGQTELRIRDHGPGLPAGQAELIFERYRRGEHTSPVPGGTGLGLYVARQIVQAHDGKLWLAEHGPDGCTFI
LTLPTVT
>Mature_647_residues
MKRVSAIFAAVRRCRPRLLAGWLLSCGLLLLLVAPQAQAATRQVGIDIPVQWYADDSGQMTLDRFAALPADQLATTRQIP
SFGYSRKTWWLRSELPGTWFAGEPRWLQLGPTFVDHLTIYYRPLGSDGPWTQRIFGDRDGARGSDLHYRERVLILPPPPT
DAGYELVFRLQSTSTLILLASLSSAQAFVQRATADTAFWSFYFGLAAVASGVALWLALALRRRLLWGICLFSLNYPLVAA
LHGFPEWFFGHAALPFQDFMISSLSLFSYATALWLHSEIFDLKKNMPRLHQLLIAAVILNLVLQVSIPLGFYGFAMQIEG
VVFIIITPVLLFTSWWLWRKKAIDRTTLLLGLLPPFYVAAAVLVQLSIHGIIPFHMAIYSLWQYALIVHIITVLIIAILR
VRAENRQLEQKQRLARELQIEREASFHQRQFMGMVAHEFRTPLAVIQAALENLRLSAASTSQEARFDRIGRAATRLVQLT
DNCLADARLASHDLHVERQQTALLTVINMAASVVAISHDHYLNIRQHGAVESPQLQADAGLLCIAIANLLDNAVKYSPPG
EIAIDIHSDAGQTELRIRDHGPGLPAGQAELIFERYRRGEHTSPVPGGTGLGLYVARQIVQAHDGKLWLAEHGPDGCTFI
LTLPTVT

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=30.7377049180328, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=25.6809338521401, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=25.296442687747, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789149, Length=245, Percent_Identity=27.7551020408163, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=222, Percent_Identity=27.9279279279279, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788393, Length=223, Percent_Identity=27.3542600896861, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787374, Length=225, Percent_Identity=28, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=24.0506329113924, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790436, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790551, Length=227, Percent_Identity=29.9559471365639, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=23.3870967741935, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786783, Length=240, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72227; Mature: 72227

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVSAIFAAVRRCRPRLLAGWLLSCGLLLLLVAPQAQAATRQVGIDIPVQWYADDSGQM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCE
TLDRFAALPADQLATTRQIPSFGYSRKTWWLRSELPGTWFAGEPRWLQLGPTFVDHLTIY
EHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCEECCCCCEEEECCHHHHCEEEE
YRPLGSDGPWTQRIFGDRDGARGSDLHYRERVLILPPPPTDAGYELVFRLQSTSTLILLA
EEECCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCEEEEEE
SLSSAQAFVQRATADTAFWSFYFGLAAVASGVALWLALALRRRLLWGICLFSLNYPLVAA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LHGFPEWFFGHAALPFQDFMISSLSLFSYATALWLHSEIFDLKKNMPRLHQLLIAAVILN
HHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LVLQVSIPLGFYGFAMQIEGVVFIIITPVLLFTSWWLWRKKAIDRTTLLLGLLPPFYVAA
HHHHHHCCCCHHHHHEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AVLVQLSIHGIIPFHMAIYSLWQYALIVHIITVLIIAILRVRAENRQLEQKQRLARELQI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EREASFHQRQFMGMVAHEFRTPLAVIQAALENLRLSAASTSQEARFDRIGRAATRLVQLT
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
DNCLADARLASHDLHVERQQTALLTVINMAASVVAISHDHYLNIRQHGAVESPQLQADAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCEEEEHHCCCCCCCCCCCCCC
LLCIAIANLLDNAVKYSPPGEIAIDIHSDAGQTELRIRDHGPGLPAGQAELIFERYRRGE
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCC
HTSPVPGGTGLGLYVARQIVQAHDGKLWLAEHGPDGCTFILTLPTVT
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCC
>Mature Secondary Structure
MKRVSAIFAAVRRCRPRLLAGWLLSCGLLLLLVAPQAQAATRQVGIDIPVQWYADDSGQM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCE
TLDRFAALPADQLATTRQIPSFGYSRKTWWLRSELPGTWFAGEPRWLQLGPTFVDHLTIY
EHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCEECCCCCEEEECCHHHHCEEEE
YRPLGSDGPWTQRIFGDRDGARGSDLHYRERVLILPPPPTDAGYELVFRLQSTSTLILLA
EEECCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCEEEEEE
SLSSAQAFVQRATADTAFWSFYFGLAAVASGVALWLALALRRRLLWGICLFSLNYPLVAA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LHGFPEWFFGHAALPFQDFMISSLSLFSYATALWLHSEIFDLKKNMPRLHQLLIAAVILN
HHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LVLQVSIPLGFYGFAMQIEGVVFIIITPVLLFTSWWLWRKKAIDRTTLLLGLLPPFYVAA
HHHHHHCCCCHHHHHEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AVLVQLSIHGIIPFHMAIYSLWQYALIVHIITVLIIAILRVRAENRQLEQKQRLARELQI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EREASFHQRQFMGMVAHEFRTPLAVIQAALENLRLSAASTSQEARFDRIGRAATRLVQLT
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
DNCLADARLASHDLHVERQQTALLTVINMAASVVAISHDHYLNIRQHGAVESPQLQADAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCEEEEHHCCCCCCCCCCCCCC
LLCIAIANLLDNAVKYSPPGEIAIDIHSDAGQTELRIRDHGPGLPAGQAELIFERYRRGE
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCC
HTSPVPGGTGLGLYVARQIVQAHDGKLWLAEHGPDGCTFILTLPTVT
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]