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The map label for this gene is galF

Identifier: 238895634

GI number: 238895634

Start: 3545674

End: 3546570

Strand: Reverse

Name: galF

Synonym: KP1_3726

Alternate gene names: 238895634

Gene position: 3546570-3545674 (Counterclockwise)

Preceding gene: 238895636

Following gene: 238895633

Centisome position: 67.57

GC content: 59.09

Gene sequence:

>897_bases
ATGAATATGGCGAATTTGAAAGCGGTTATTCCGGTCGCAGGACTAGGCATGCATATGCTGCCGGCCACAAAGGCAATTCC
AAAGGAGATGCTGCCGATCGTTGATAAGCCAATGATTCAGTACATCGTTGACGAAATCGTCGCCGCCGGGATCAAAGAGA
TTGTTCTGGTGACGCACTCCTCGAAGAACGCGGTGGAAAACCACTTCGACACCTCCTACGAGCTGGAAGCCCTGCTGGAA
CAGCGCGTGAAGCGCCAGCTACTGGCGGAAGTGCAGGCCATTTGCCCGCCGGGCGTGACCATCATGAACGTGCGTCAGGC
GCAGCCGCTGGGCCTGGGCCACTCTATCCTCTGCGCCCGCCCGGTAGTCGGCGACAACCCGTTTGTGGTGGTCCTGCCGG
ATATCATCCTTGACGGCGGCACCGCTGACCCGCTGCGCTATAACCTCGCCGCTATGATCGCCCGCTTTAACGAGACCGGC
CGCAGCCAGGTGCTGGCGAAACGCATGCCGGGCGATCTCTCCGAATACTCCGTCATCCAGACCAAAGAGCCGATGGTGGC
TGAAGGCCAGGTGGCGCGTATCGTCGAGTTTATTGAAAAACCGGACGAACCGCAGACCCTGGACTCCGATCTGATGGCGG
TGGGGCGCTACGTGCTGTCGGCGGATATCTGGGCCGAACTGGAACGTACCGAGCCGGGCGCATGGGGCCGTATCCAGCTG
ACCGACGCCATTGCCGAACTGGCGAAGAAGCAGTCCGTCGACGCGATGCTGATGACCGGCGAAAGCTACGACTGCGGGAA
GAAAATGGGCTACATGCAGGCCTTCGTCACCTACGGGATGCGTAACCTGAAAGAAGGCGCCAAATTCCGCGAAAGTATTA
AAAAACTGCTGGCCTGA

Upstream 100 bases:

>100_bases
GGGCAGATGCCCGGGCAGTATCCGTGTATTATCAGTTCCAATGGATTTGTGACATGTACAATTTTGCAAAACCGCGTGTT
TTGCAACCAAACAGGTGAAG

Downstream 100 bases:

>100_bases
GCGCCAGCCTGAAACCGAGCGGCAAGTCTGAAGCATTCGTCCTGCCGCTCATAACGTTATGCAGAAATTATTCATAACGC
GAATGTTATAACGATTGTAA

Product: UTP--glucose-1-phosphate uridylyltransferase subunit GalF

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLE
QRVKRQLLAEVQAICPPGVTIMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNETG
RSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLSADIWAELERTEPGAWGRIQL
TDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTYGMRNLKEGAKFRESIKKLLA

Sequences:

>Translated_298_residues
MNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLE
QRVKRQLLAEVQAICPPGVTIMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNETG
RSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLSADIWAELERTEPGAWGRIQL
TDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTYGMRNLKEGAKFRESIKKLLA
>Mature_298_residues
MNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEIVLVTHSSKNAVENHFDTSYELEALLE
QRVKRQLLAEVQAICPPGVTIMNVRQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNETG
RSQVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLSADIWAELERTEPGAWGRIQL
TDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTYGMRNLKEGAKFRESIKKLLA

Specific function: Lipopolysaccharide biosynthesis. [C]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family

Homologues:

Organism=Homo sapiens, GI11761619, Length=288, Percent_Identity=23.9583333333333, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI11761621, Length=288, Percent_Identity=23.9583333333333, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788355, Length=296, Percent_Identity=89.527027027027, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI1787488, Length=290, Percent_Identity=60, Blast_Score=345, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GALF_KLEPN (Q48447)

Other databases:

- EMBL:   D21242
- PIR:   A56146
- ProteinModelPortal:   Q48447
- SMR:   Q48447
- BRENDA:   2.7.7.9
- InterPro:   IPR005774
- InterPro:   IPR005835
- TIGRFAMs:   TIGR01105

Pfam domain/function: PF00483 NTP_transferase

EC number: =2.7.7.9

Molecular weight: Translated: 32779; Mature: 32779

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEIVLVTHS
CCCCHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHEEEEECC
SKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVTIMNVRQAQPLGLGHSILCAR
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHEEC
PVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNETGRSQVLAKRMPGDLSEYSVIQ
CCCCCCCEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCEEE
TKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLSADIWAELERTEPGAWGRIQL
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEH
TDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTYGMRNLKEGAKFRESIKKLLA
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNMANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEIVLVTHS
CCCCHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHEEEEECC
SKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVTIMNVRQAQPLGLGHSILCAR
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHEEC
PVVGDNPFVVVLPDIILDGGTADPLRYNLAAMIARFNETGRSQVLAKRMPGDLSEYSVIQ
CCCCCCCEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCEEE
TKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLSADIWAELERTEPGAWGRIQL
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEH
TDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTYGMRNLKEGAKFRESIKKLLA
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896702