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The map label for this gene is sbcB [H]

Identifier: 238895590

GI number: 238895590

Start: 3492287

End: 3493711

Strand: Direct

Name: sbcB [H]

Synonym: KP1_3673

Alternate gene names: 238895590

Gene position: 3492287-3493711 (Clockwise)

Preceding gene: 238895583

Following gene: 238895592

Centisome position: 66.54

GC content: 60.07

Gene sequence:

>1425_bases
ATGCAAGATAGCGTCAACCAGCCCGGATTTTTATTCCACGATTATGAAACCTTCGGCACCAGCCCTTCCCTCGACCGGCC
GGCGCAGTTCGCCGCCATCCGCACCGACGCGGAGCTGAATGTGCTCGGCGAGCCCGAAGTGTTTTACTGCAAACCCGCTG
ACGATTACCTGCCGCAGCCGCAGGCGGTGATGATCACCGGGATCACCCCGCAGGAAGCGCTAGCCAAAGGGGATAATGAG
GCCACATTTGCCCGCCGCATCCACGATCTGTTCACGGTGCCGCAAACCTGTATCGTCGGCTATAACAACGTGCGCTTTGA
TGACGAAGTGACGCGGAATATCTTCTATCGCAACTTCTATGACCCTTATGCCTGGAGCTGGCAGCACGATAACTCGCGCT
GGGATCTGCTCGACGTGATGCGCGCCTGCTATGCCCTGCGCCCGGAAGGGATCGCCTGGCCAGAGAATGACGAAGGGTTG
CCGAGCTTCCGGCTTGAACATCTGACCGTCGCCAACGGTATTGAACACCAGAACGCCCATGACGCGATGGCCGACGTATA
CGCCACCATCGCCATGGCGAAGCTGGTGAAAACCCGGCAGCCGCGGCTGTTTGATTATCTCTACAGCCACCGCAATAAGC
GCAAGCTGGCGACGCTTATCGACGTGCCGCAGATGAAGCCCCTGGTGCATGTCTCCGGCATGTTTGGCGCCGCGCGCGGC
AATACCAGCCTGGTGGCGCCCCTGGCCTGGCATCCGGAAAACCGCAATGCGGTGATTATGGTCGATCTGGCGGGCGATAT
GGCGCCGCTGCTGGAACTGGATGCCGATGCCCTGCGCGAGCGGCTTTACACCCCGCGCGCCGAGCTTGGCGATCTGCCGG
CAGCGCCGATTAAGCTGGTGCATCTTAATAAATGTCCGGTACTGGCCCAGGCCAATACCCTGCGCCCGCAGGATGCCGAC
CGGCTGGGGATCTCTATTCAGCGCTGTCTGGAGAACGCCCAGCTGCTGCGGGCGAATCCGCAGGTGCGCGAGAAGGTAGT
GGCGGTCTATGCTGAAGCCGAACCCTTCGTGCCGTCCGAAAACGTCGACGCCCAGCTGTACAATGGGTTCTTTAGCGATG
CCGACCGCGCGGCGATGAAAATCGTGCTGGAAACCGAACCGCGCAATCTGCCGGCGCTGGATATCACCTTCGCCGACCAG
CGTATCGAACGCCTGCTGTTTAACTACCGGGCGCGCAACTTCCCCGGCACGCTCGATGAACATGAGCAGCAGCGCTGGTT
AGAGCACCGTCGTCAGGTGTTTACGCCGGCGTTTTTGCAGGCCTATGCCGATGAGCTGCAGATGCTGTATCAGCAGTATG
CGGATGATAAAGAGAAGCTGGCGCAACTGAAAGCGCTGTGGCAGTACGCGCAGGATATTGTCTGA

Upstream 100 bases:

>100_bases
ATATGACACAGCAGAGGAAGTTGCTTGCCGCGACCCTTCTGATGACCGGGCAAATCGTTTACCATACCGGTCGCACGCCA
CCACGGATAATGAACAGACT

Downstream 100 bases:

>100_bases
TTGGCTGAAATTCCCGGGTTGCGGCTAACGCCTTACCCGGGCTACAAACGATGACCGGGGAGGACGCCTGACCGTAGGCC
CGCGCAAGCGCAGCGCCGCC

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MQDSVNQPGFLFHDYETFGTSPSLDRPAQFAAIRTDAELNVLGEPEVFYCKPADDYLPQPQAVMITGITPQEALAKGDNE
ATFARRIHDLFTVPQTCIVGYNNVRFDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGIAWPENDEGL
PSFRLEHLTVANGIEHQNAHDAMADVYATIAMAKLVKTRQPRLFDYLYSHRNKRKLATLIDVPQMKPLVHVSGMFGAARG
NTSLVAPLAWHPENRNAVIMVDLAGDMAPLLELDADALRERLYTPRAELGDLPAAPIKLVHLNKCPVLAQANTLRPQDAD
RLGISIQRCLENAQLLRANPQVREKVVAVYAEAEPFVPSENVDAQLYNGFFSDADRAAMKIVLETEPRNLPALDITFADQ
RIERLLFNYRARNFPGTLDEHEQQRWLEHRRQVFTPAFLQAYADELQMLYQQYADDKEKLAQLKALWQYAQDIV

Sequences:

>Translated_474_residues
MQDSVNQPGFLFHDYETFGTSPSLDRPAQFAAIRTDAELNVLGEPEVFYCKPADDYLPQPQAVMITGITPQEALAKGDNE
ATFARRIHDLFTVPQTCIVGYNNVRFDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGIAWPENDEGL
PSFRLEHLTVANGIEHQNAHDAMADVYATIAMAKLVKTRQPRLFDYLYSHRNKRKLATLIDVPQMKPLVHVSGMFGAARG
NTSLVAPLAWHPENRNAVIMVDLAGDMAPLLELDADALRERLYTPRAELGDLPAAPIKLVHLNKCPVLAQANTLRPQDAD
RLGISIQRCLENAQLLRANPQVREKVVAVYAEAEPFVPSENVDAQLYNGFFSDADRAAMKIVLETEPRNLPALDITFADQ
RIERLLFNYRARNFPGTLDEHEQQRWLEHRRQVFTPAFLQAYADELQMLYQQYADDKEKLAQLKALWQYAQDIV
>Mature_474_residues
MQDSVNQPGFLFHDYETFGTSPSLDRPAQFAAIRTDAELNVLGEPEVFYCKPADDYLPQPQAVMITGITPQEALAKGDNE
ATFARRIHDLFTVPQTCIVGYNNVRFDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGIAWPENDEGL
PSFRLEHLTVANGIEHQNAHDAMADVYATIAMAKLVKTRQPRLFDYLYSHRNKRKLATLIDVPQMKPLVHVSGMFGAARG
NTSLVAPLAWHPENRNAVIMVDLAGDMAPLLELDADALRERLYTPRAELGDLPAAPIKLVHLNKCPVLAQANTLRPQDAD
RLGISIQRCLENAQLLRANPQVREKVVAVYAEAEPFVPSENVDAQLYNGFFSDADRAAMKIVLETEPRNLPALDITFADQ
RIERLLFNYRARNFPGTLDEHEQQRWLEHRRQVFTPAFLQAYADELQMLYQQYADDKEKLAQLKALWQYAQDIV

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=474, Percent_Identity=85.4430379746835, Blast_Score=857, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54147; Mature: 54147

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDSVNQPGFLFHDYETFGTSPSLDRPAQFAAIRTDAELNVLGEPEVFYCKPADDYLPQP
CCCCCCCCCEEEECHHHCCCCCCCCCCCCEEEEECCCCEEEECCCCEEEECCCHHHCCCC
QAVMITGITPQEALAKGDNEATFARRIHDLFTVPQTCIVGYNNVRFDDEVTRNIFYRNFY
CEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHCCC
DPYAWSWQHDNSRWDLLDVMRACYALRPEGIAWPENDEGLPSFRLEHLTVANGIEHQNAH
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHH
DAMADVYATIAMAKLVKTRQPRLFDYLYSHRNKRKLATLIDVPQMKPLVHVSGMFGAARG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCEEECCCCCCCCC
NTSLVAPLAWHPENRNAVIMVDLAGDMAPLLELDADALRERLYTPRAELGDLPAAPIKLV
CCCEEEEEEECCCCCCEEEEEEECCCCHHHHHCCHHHHHHHHCCCCHHHCCCCCCCEEEE
HLNKCPVLAQANTLRPQDADRLGISIQRCLENAQLLRANPQVREKVVAVYAEAEPFVPSE
EECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCC
NVDAQLYNGFFSDADRAAMKIVLETEPRNLPALDITFADQRIERLLFNYRARNFPGTLDE
CCCHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCH
HEQQRWLEHRRQVFTPAFLQAYADELQMLYQQYADDKEKLAQLKALWQYAQDIV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDSVNQPGFLFHDYETFGTSPSLDRPAQFAAIRTDAELNVLGEPEVFYCKPADDYLPQP
CCCCCCCCCEEEECHHHCCCCCCCCCCCCEEEEECCCCEEEECCCCEEEECCCHHHCCCC
QAVMITGITPQEALAKGDNEATFARRIHDLFTVPQTCIVGYNNVRFDDEVTRNIFYRNFY
CEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHCCC
DPYAWSWQHDNSRWDLLDVMRACYALRPEGIAWPENDEGLPSFRLEHLTVANGIEHQNAH
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHH
DAMADVYATIAMAKLVKTRQPRLFDYLYSHRNKRKLATLIDVPQMKPLVHVSGMFGAARG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCEEECCCCCCCCC
NTSLVAPLAWHPENRNAVIMVDLAGDMAPLLELDADALRERLYTPRAELGDLPAAPIKLV
CCCEEEEEEECCCCCCEEEEEEECCCCHHHHHCCHHHHHHHHCCCCHHHCCCCCCCEEEE
HLNKCPVLAQANTLRPQDADRLGISIQRCLENAQLLRANPQVREKVVAVYAEAEPFVPSE
EECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCC
NVDAQLYNGFFSDADRAAMKIVLETEPRNLPALDITFADQRIERLLFNYRARNFPGTLDE
CCCHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCH
HEQQRWLEHRRQVFTPAFLQAYADELQMLYQQYADDKEKLAQLKALWQYAQDIV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]