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The map label for this gene is argS [H]

Identifier: 238895450

GI number: 238895450

Start: 3334983

End: 3336716

Strand: Direct

Name: argS [H]

Synonym: KP1_3519

Alternate gene names: 238895450

Gene position: 3334983-3336716 (Clockwise)

Preceding gene: 238895447

Following gene: 238895453

Centisome position: 63.54

GC content: 59.11

Gene sequence:

>1734_bases
GTGAATATTCAGGCTCTTCTCTCAGAAAAAGTCAGCCAGGCCCTGATCGCGGCAGGCGCGCCTGCCGATTGCGAACCCCA
GGTCCGCCAGTCAGCAAAAGTTCAGTTCGGCGACTATCAGGCCAACGGCGTGATGGCTGTCGCCAAAAAGCTGGGTATGG
CGCCGCGACAACTTGCAGAGCAGGTACTGTCTCATCTTGACCTCAACGGCATTGCCAACAAGGTTGAAATCGCCGGGCCG
GGCTTTATCAATATTTTCCTCGACCCCGCGTTTCTGGCGGACAACGTCAACCGCGCGCTGCAGTCTGAGCGCCTGGGCGT
CACGAAACCGCAGGCGCAGACTATCGTCGTCGACTACTCGGCACCCAACGTAGCGAAAGAGATGCACGTCGGCCATCTGC
GTTCGACCATCATTGGCGATGCTTCAGTCCGTACCCTGGAGTTCCTGGGTCATAAGGTGATCCGCGCCAACCACGTCGGC
GACTGGGGCACCCAGTTCGGGATGCTGATCGCGTATCTGGAAAAACAGCAGCAGGAAAACGCCGGCGAAATGGCCCTGGC
CGACCTCGAAGGTTTCTATCGCGAAGCGAAAAAGCACTATGACGAAGACGAAGCCTTCGCCGAGCGCGCGCGCAGCTACG
TGGTTAAGCTGCAGGGTGGTGATGAGTACTTCCTGCAGATGTGGCGTAAGCTGGTCGACATCACCATGTCGCAGAACCAG
ATCACCTACGATCGCCTGAACGTCACCCTGACCCGCGATGACGTGATGGGTGAGAGCCTGTACAACCCGATGCTGCCGGG
GATCGTCGCCGATCTGAAAGCCAAAGGGCTGGCGGTTGAGAGCGAAGGCGCTACCGTGGTCTTCCTTGATGAGTACAAAA
ACAAGGAAGGCGAACCGATGGGCGTCATCATCCAGAAAAAGGATGGCGGCTACCTCTATACCACCACCGATATCGCCTGT
GCGAAGTATCGCTATGAAACGCTGCACGCCGACCGCGTGCTCTACTACATCGACTCTCGTCAGCACCAGCACCTGATGCA
GGCGTGGACCATCGTGCGCAAGGCAGGCTACGTGCCGGACTCCGTGCCGCTGGAGCACCATATGTTCGGTATGATGCTTG
GGAAAGACGGCAAGCCGTTTAAAACCCGCGCCGGCGGTACCGTGAAGCTGGCGGATCTGCTGGACGAAGCGCTGGAGCGC
GCCCGTCGCCTGGTGGCCGAGAAGAACCCGGATATGTCGGCTGACGAGCTGGAAAATCTGGCGAAAGTGGTGGGTATCGG
CGCGGTTAAATATGCCGACCTGTCGAAAAACCGCACCACCGACTACGTCTTCGACTGGGATAATATGCTGGCGTTCGAAG
GCAACACCGCGCCGTATATGCAGTATGCCTATACCCGCGTGCTCTCCGTGTTCCGCAAAGCCGGCATCGACGAAAACGCG
ATGATCGACGCGCCGGTGGTCATCGCCGAAGATCGCGAAGCTCAGCTGGCCGCGCGCCTGCTGCAGTTTGAAGAGACCCT
CTCCGTGGTCGCTCGCGAAGGGACGCCGCACGTGATGTGCGCCTACCTCTACGATCTGGCGGGCCTGTTCTCCGGCTTCT
ACGAGCACTGCCCGATCCTCAGCGCGGAAAGCGAAGAGACCCGTAACAGCCGTCTGAAGCTGGCGCTGCTCACGGCGAAA
ACCCTCAAGCTGGGTCTTGATACCCTCGGTATCGAAACCGTCGAGCGTATGTAA

Upstream 100 bases:

>100_bases
CTGACGGACGGGGACAAATGCAGTATACTCCCGCCCTAATTTGTCCACATTATGGCGCCGCCTCCCTCGGGGGCAGGCGC
ATTACACGTAAGGTATTCCG

Downstream 100 bases:

>100_bases
CAAGCAACCCGGCGAAAGCCGGGTTAGTTTTATTCGGCGCCTCGCCAGCGGGGCGCCCTGCTCAGAAGTACTTGCGTAGA
TACTCCGTCAGACAAAGGAT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIQALLSEKVSQALIAAGAPADCEPQVRQSAKVQFGDYQANGVMAVAKKLGMAPRQLAEQVLSHLDLNGIANKVEIAGP
GFINIFLDPAFLADNVNRALQSERLGVTKPQAQTIVVDYSAPNVAKEMHVGHLRSTIIGDASVRTLEFLGHKVIRANHVG
DWGTQFGMLIAYLEKQQQENAGEMALADLEGFYREAKKHYDEDEAFAERARSYVVKLQGGDEYFLQMWRKLVDITMSQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEYKNKEGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPDSVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMSADELENLAKVVGIGAVKYADLSKNRTTDYVFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAGIDENA
MIDAPVVIAEDREAQLAARLLQFEETLSVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAESEETRNSRLKLALLTAK
TLKLGLDTLGIETVERM

Sequences:

>Translated_577_residues
MNIQALLSEKVSQALIAAGAPADCEPQVRQSAKVQFGDYQANGVMAVAKKLGMAPRQLAEQVLSHLDLNGIANKVEIAGP
GFINIFLDPAFLADNVNRALQSERLGVTKPQAQTIVVDYSAPNVAKEMHVGHLRSTIIGDASVRTLEFLGHKVIRANHVG
DWGTQFGMLIAYLEKQQQENAGEMALADLEGFYREAKKHYDEDEAFAERARSYVVKLQGGDEYFLQMWRKLVDITMSQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEYKNKEGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPDSVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMSADELENLAKVVGIGAVKYADLSKNRTTDYVFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAGIDENA
MIDAPVVIAEDREAQLAARLLQFEETLSVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAESEETRNSRLKLALLTAK
TLKLGLDTLGIETVERM
>Mature_577_residues
MNIQALLSEKVSQALIAAGAPADCEPQVRQSAKVQFGDYQANGVMAVAKKLGMAPRQLAEQVLSHLDLNGIANKVEIAGP
GFINIFLDPAFLADNVNRALQSERLGVTKPQAQTIVVDYSAPNVAKEMHVGHLRSTIIGDASVRTLEFLGHKVIRANHVG
DWGTQFGMLIAYLEKQQQENAGEMALADLEGFYREAKKHYDEDEAFAERARSYVVKLQGGDEYFLQMWRKLVDITMSQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEYKNKEGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPDSVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMSADELENLAKVVGIGAVKYADLSKNRTTDYVFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAGIDENA
MIDAPVVIAEDREAQLAARLLQFEETLSVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAESEETRNSRLKLALLTAK
TLKLGLDTLGIETVERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=599, Percent_Identity=37.7295492487479, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI197100773, Length=480, Percent_Identity=31.0416666666667, Blast_Score=196, Evalue=4e-50,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=92.2010398613518, Blast_Score=1111, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=598, Percent_Identity=37.4581939799331, Blast_Score=363, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71985068, Length=558, Percent_Identity=37.9928315412186, Blast_Score=355, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI17532153, Length=383, Percent_Identity=27.6762402088773, Blast_Score=148, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320548, Length=544, Percent_Identity=34.7426470588235, Blast_Score=262, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6321883, Length=538, Percent_Identity=29.368029739777, Blast_Score=222, Evalue=1e-58,
Organism=Drosophila melanogaster, GI18859963, Length=567, Percent_Identity=37.2134038800705, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI28571570, Length=482, Percent_Identity=30.0829875518672, Blast_Score=174, Evalue=2e-43,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64243; Mature: 64243

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQALLSEKVSQALIAAGAPADCEPQVRQSAKVQFGDYQANGVMAVAKKLGMAPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHH
QVLSHLDLNGIANKVEIAGPGFINIFLDPAFLADNVNRALQSERLGVTKPQAQTIVVDYS
HHHHHCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
APNVAKEMHVGHLRSTIIGDASVRTLEFLGHKVIRANHVGDWGTQFGMLIAYLEKQQQEN
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHCC
AGEMALADLEGFYREAKKHYDEDEAFAERARSYVVKLQGGDEYFLQMWRKLVDITMSQNQ
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCE
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEYKNKEGEPM
EEEEEEEEEEECCHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPD
EEEEEECCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMSADELENL
CCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AKVVGIGAVKYADLSKNRTTDYVFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAGIDENA
HHHHHCCCEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
MIDAPVVIAEDREAQLAARLLQFEETLSVVAREGTPHVMCAYLYDLAGLFSGFYEHCPIL
EECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
SAESEETRNSRLKLALLTAKTLKLGLDTLGIETVERM
CCCCCHHHCCEEEEEEEEHHHHHHHHHHHCHHHHHCC
>Mature Secondary Structure
MNIQALLSEKVSQALIAAGAPADCEPQVRQSAKVQFGDYQANGVMAVAKKLGMAPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHH
QVLSHLDLNGIANKVEIAGPGFINIFLDPAFLADNVNRALQSERLGVTKPQAQTIVVDYS
HHHHHCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
APNVAKEMHVGHLRSTIIGDASVRTLEFLGHKVIRANHVGDWGTQFGMLIAYLEKQQQEN
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHCC
AGEMALADLEGFYREAKKHYDEDEAFAERARSYVVKLQGGDEYFLQMWRKLVDITMSQNQ
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCE
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEYKNKEGEPM
EEEEEEEEEEECCHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPD
EEEEEECCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMSADELENL
CCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AKVVGIGAVKYADLSKNRTTDYVFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAGIDENA
HHHHHCCCEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
MIDAPVVIAEDREAQLAARLLQFEETLSVVAREGTPHVMCAYLYDLAGLFSGFYEHCPIL
EECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
SAESEETRNSRLKLALLTAKTLKLGLDTLGIETVERM
CCCCCHHHCCEEEEEEEEHHHHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA