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The map label for this gene is kdgR [H]

Identifier: 238895403

GI number: 238895403

Start: 3288917

End: 3289708

Strand: Reverse

Name: kdgR [H]

Synonym: KP1_3470

Alternate gene names: 238895403

Gene position: 3289708-3288917 (Counterclockwise)

Preceding gene: 238895405

Following gene: 238895401

Centisome position: 62.68

GC content: 54.42

Gene sequence:

>792_bases
ATGGCAGGTGCAGATTTGGATAAACAGCCAGATTCTGTCTCTTCGGTATTGAAGGTTTTCGGCATCCTACAGGCGCTGGG
TGAAGAGCGTGAAATTGGCATTACCGAACTGTCCCAGCGCGTCATGATGTCGAAAAGCACCGTTTATCGCTTTTTACAGA
CCATGAAATCACTGGGCTATGTGGCACAGGAAGGAGAGTCTGAGAAATACTCTCTCACCCTCAAGCTGTTCGAACTGGGC
GCGCGCGCGCTGCAGAACGTCGACCTGGTGCGCAGCGCCGATATTCAGATGCGCGAACTTTCGCGACTGACGAAAGAGAC
CATCCATCTTGGGGCGCTGGATGAAGACAGTATCGTCTACATCCATAAAATTGACTCGATGTATAACCTGCGGATGTACT
CGCGTATTGGCCGCCGCAACCCGCTGTACAGTACCGCGATTGGCAAGGTGCTGCTGGCATGGCGCGATCGCAGCGAAGTG
GAGCAGATCCTCGACGGCGTGGAGTATAAGCGCAGCACCGAGCGGACCATTACCAGCACCGAGGAGTTGCTAAAAGTGCT
GGATGGCGTTCGCGAGCAGGGCTATGGCGAGGATAATGAGGAACAGGAAGAGGGGCTGCGCTGCATTGGCGTGCCGGTGT
TTGACCGTTTCGGCGTGGTCATCGCCGGGCTGAGCATCTCTTTCCCAACGCTACGTTTCTCTGAAGAACGCTTGCATGAA
TACGTGGCGATGCTCCATCAGGCGGCGCGTAAGATTTCTGAACAAATGGGATACAACGACTATCCGTTCTGA

Upstream 100 bases:

>100_bases
TTGTAACGAAGTGGCAGAAGAATGATTGCGGCTCAGAGGCGGCGAATTTATAATAAAAACCGGTTCTAATTTTTATAAAA
CAGTTACGACGAGGTGATAA

Downstream 100 bases:

>100_bases
GGCGGCGGATACCGGGTTGGCGACCGCGGCGCTACGTCGCGATCGCCGGTTCGATGTTAGCCGTTATCAACCACGGTTGT
GCTTTTACGCAGCAGAGGGC

Product: putative IclR-family transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MAGADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKSLGYVAQEGESEKYSLTLKLFELG
ARALQNVDLVRSADIQMRELSRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRSEV
EQILDGVEYKRSTERTITSTEELLKVLDGVREQGYGEDNEEQEEGLRCIGVPVFDRFGVVIAGLSISFPTLRFSEERLHE
YVAMLHQAARKISEQMGYNDYPF

Sequences:

>Translated_263_residues
MAGADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKSLGYVAQEGESEKYSLTLKLFELG
ARALQNVDLVRSADIQMRELSRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRSEV
EQILDGVEYKRSTERTITSTEELLKVLDGVREQGYGEDNEEQEEGLRCIGVPVFDRFGVVIAGLSISFPTLRFSEERLHE
YVAMLHQAARKISEQMGYNDYPF
>Mature_262_residues
AGADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKSLGYVAQEGESEKYSLTLKLFELGA
RALQNVDLVRSADIQMRELSRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRSEVE
QILDGVEYKRSTERTITSTEELLKVLDGVREQGYGEDNEEQEEGLRCIGVPVFDRFGVVIAGLSISFPTLRFSEERLHEY
VAMLHQAARKISEQMGYNDYPF

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=263, Percent_Identity=94.6768060836502, Blast_Score=507, Evalue=1e-145,
Organism=Escherichia coli, GI1786468, Length=247, Percent_Identity=40.8906882591093, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789999, Length=228, Percent_Identity=32.0175438596491, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082359, Length=244, Percent_Identity=29.0983606557377, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790752, Length=226, Percent_Identity=31.4159292035398, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786715, Length=229, Percent_Identity=29.6943231441048, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1788581, Length=251, Percent_Identity=28.2868525896414, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29979; Mature: 29847

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKSLGY
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAQEGESEKYSLTLKLFELGARALQNVDLVRSADIQMRELSRLTKETIHLGALDEDSIVY
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEE
IHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRSEVEQILDGVEYKRSTERTITST
EEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EELLKVLDGVREQGYGEDNEEQEEGLRCIGVPVFDRFGVVIAGLSISFPTLRFSEERLHE
HHHHHHHHHHHHCCCCCCCCHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
YVAMLHQAARKISEQMGYNDYPF
HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AGADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKSLGY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAQEGESEKYSLTLKLFELGARALQNVDLVRSADIQMRELSRLTKETIHLGALDEDSIVY
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEE
IHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRSEVEQILDGVEYKRSTERTITST
EEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EELLKVLDGVREQGYGEDNEEQEEGLRCIGVPVFDRFGVVIAGLSISFPTLRFSEERLHE
HHHHHHHHHHHHCCCCCCCCHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
YVAMLHQAARKISEQMGYNDYPF
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]