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The map label for this gene is ldcA [H]

Identifier: 238895364

GI number: 238895364

Start: 3251269

End: 3252183

Strand: Direct

Name: ldcA [H]

Synonym: KP1_3429

Alternate gene names: 238895364

Gene position: 3251269-3252183 (Clockwise)

Preceding gene: 238895362

Following gene: 238895365

Centisome position: 61.95

GC content: 66.01

Gene sequence:

>915_bases
ATGTCTCAGTTTTATCTGGTCGCGCCATCCGGGTATTGCATCAACCAGCAGGCGGCAGCCCGCGGCGTCGAGCGTCTGCA
GCAGGCCGGACACGAGGTGGCCCACCAGCAGGTCATTCCCCGCCGGCAGCAGCGTTTCGCCGGGACTGAACATGAACGGC
TGGCCGATATTAACCAGCTGGCCCAGTTGCCCGGCCGCAACCGGATCGTCCTCGCCGTGCGCGGCGGCTACGGCGCCAGT
CGCCTGCTGCCGCATATCGACTGGCAGGGGCTGGTTGCCCGCCAGCAGCGCGACCCGCTGCTGATTTGCGGCCACAGCGA
TTTCACCGCTATCCAGTCGGGCCTGCTGGCCATGGGCAACGTCATCACCTTCAGCGGGCCAATGCTCGCCGGCAACTTCG
GCGCGGAGACCCTCGACCCGTTTACCGAGCACCATTTCTGGCAGGCGCTACGCCAGCCGGAATTCACCCTCGAATGGCCG
GGCGAAGGGCCGAACTGCCGGGTGGAAGGCACCCTGTGGGGGGGAAATCTGGCGATGCTGACCTCGCTTATCGGCACGCC
GTGGCTGCCGGCGATCCGCGACGGCATCCTGGTGGTGGAGGATATCAACGAGCACCCGTTCCGCGTCGAGCGCATGCTGC
TTCAGCTGTTGCACAGCGGCGTGCTGGCGGCGCAGAAAGCGGTGATCTTCGGCAGCTTCACCGGCAGCGCGCCGAACGAC
TATGACGCGGGATACGATTTGCCGCAGGTTTTTGATTATCTGCGCCAACAGCTCCCCCTGCCGCTGATTAGCGGACTGGA
GTTTGGCCACGAGCAGCGCACGGTGACCCTGCCGCTGGGCGCCCGCGCGCGCCTGGTGAATCAGGCGGCGGCCACCACCC
TGACGATCGGCGGCCATCCGGTGCTGACAGAATAA

Upstream 100 bases:

>100_bases
CCTGAAGGATGACGGGTGCGGACTGAAGTTAGCCACCTGGAGATGACAATCGCCATTCCAGGCGGCATCATAACCCTTTC
ATTCATAGCAAGGAATTATC

Downstream 100 bases:

>100_bases
ATTTCCCGAACGCATAGGCGGATCCCCTGCGAATTGTTAAAATAGTGTCACTTTTAGCCATTTTTTCACGCCAGTCAGGG
AGTACGTGAACATTGGACGC

Product: L,D-carboxypeptidase A

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSQFYLVAPSGYCINQQAAARGVERLQQAGHEVAHQQVIPRRQQRFAGTEHERLADINQLAQLPGRNRIVLAVRGGYGAS
RLLPHIDWQGLVARQQRDPLLICGHSDFTAIQSGLLAMGNVITFSGPMLAGNFGAETLDPFTEHHFWQALRQPEFTLEWP
GEGPNCRVEGTLWGGNLAMLTSLIGTPWLPAIRDGILVVEDINEHPFRVERMLLQLLHSGVLAAQKAVIFGSFTGSAPND
YDAGYDLPQVFDYLRQQLPLPLISGLEFGHEQRTVTLPLGARARLVNQAAATTLTIGGHPVLTE

Sequences:

>Translated_304_residues
MSQFYLVAPSGYCINQQAAARGVERLQQAGHEVAHQQVIPRRQQRFAGTEHERLADINQLAQLPGRNRIVLAVRGGYGAS
RLLPHIDWQGLVARQQRDPLLICGHSDFTAIQSGLLAMGNVITFSGPMLAGNFGAETLDPFTEHHFWQALRQPEFTLEWP
GEGPNCRVEGTLWGGNLAMLTSLIGTPWLPAIRDGILVVEDINEHPFRVERMLLQLLHSGVLAAQKAVIFGSFTGSAPND
YDAGYDLPQVFDYLRQQLPLPLISGLEFGHEQRTVTLPLGARARLVNQAAATTLTIGGHPVLTE
>Mature_303_residues
SQFYLVAPSGYCINQQAAARGVERLQQAGHEVAHQQVIPRRQQRFAGTEHERLADINQLAQLPGRNRIVLAVRGGYGASR
LLPHIDWQGLVARQQRDPLLICGHSDFTAIQSGLLAMGNVITFSGPMLAGNFGAETLDPFTEHHFWQALRQPEFTLEWPG
EGPNCRVEGTLWGGNLAMLTSLIGTPWLPAIRDGILVVEDINEHPFRVERMLLQLLHSGVLAAQKAVIFGSFTGSAPNDY
DAGYDLPQVFDYLRQQLPLPLISGLEFGHEQRTVTLPLGARARLVNQAAATTLTIGGHPVLTE

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=302, Percent_Identity=72.5165562913907, Blast_Score=455, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 33418; Mature: 33286

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFYLVAPSGYCINQQAAARGVERLQQAGHEVAHQQVIPRRQQRFAGTEHERLADINQL
CCCEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AQLPGRNRIVLAVRGGYGASRLLPHIDWQGLVARQQRDPLLICGHSDFTAIQSGLLAMGN
HHCCCCCEEEEEEECCCCHHHHCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCC
VITFSGPMLAGNFGAETLDPFTEHHFWQALRQPEFTLEWPGEGPNCRVEGTLWGGNLAML
EEEECCCEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCHHHHH
TSLIGTPWLPAIRDGILVVEDINEHPFRVERMLLQLLHSGVLAAQKAVIFGSFTGSAPND
HHHHCCCCCHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCC
YDAGYDLPQVFDYLRQQLPLPLISGLEFGHEQRTVTLPLGARARLVNQAAATTLTIGGHP
CCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHEEEEECCCC
VLTE
CCCC
>Mature Secondary Structure 
SQFYLVAPSGYCINQQAAARGVERLQQAGHEVAHQQVIPRRQQRFAGTEHERLADINQL
CCEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AQLPGRNRIVLAVRGGYGASRLLPHIDWQGLVARQQRDPLLICGHSDFTAIQSGLLAMGN
HHCCCCCEEEEEEECCCCHHHHCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCC
VITFSGPMLAGNFGAETLDPFTEHHFWQALRQPEFTLEWPGEGPNCRVEGTLWGGNLAML
EEEECCCEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCHHHHH
TSLIGTPWLPAIRDGILVVEDINEHPFRVERMLLQLLHSGVLAAQKAVIFGSFTGSAPND
HHHHCCCCCHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCC
YDAGYDLPQVFDYLRQQLPLPLISGLEFGHEQRTVTLPLGARARLVNQAAATTLTIGGHP
CCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHEEEEECCCC
VLTE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]