Click here to switch to the map view.

The map label for this gene is pkn1 [H]

Identifier: 238895322

GI number: 238895322

Start: 3205044

End: 3205934

Strand: Reverse

Name: pkn1 [H]

Synonym: KP1_3381

Alternate gene names: 238895322

Gene position: 3205934-3205044 (Counterclockwise)

Preceding gene: 238895323

Following gene: 238895321

Centisome position: 61.08

GC content: 41.08

Gene sequence:

>891_bases
ATGAGAAAATTAATCGTAGTTGCTTCCGTTGCTGCTGGTTTACTGACAGGGTGCGATCAGGGAAATACCACCGGGAGTGA
AAAAGCAGCTAAAGCACTTGTGGATAAATCGGTCTCTAATATGGTCCCCGTTCAGGGTGGTGAGTTTTTAATGGGTGATT
TTGGTCCATTAGTTGGTGAAAAATTACCTTTCAGCATACAACAGGATGATAAAAATTTACATAAGGTTATTTTAAGTGAT
TTTTCGATATCAAAATATAAAGTCACTAACGATGATTTTAATGTTTATTTGAAAGTAACAGATAAAAAAAATCCACCTGT
GGATATACTGGCAAAACGTCATCCTTCTCTGCTAAAGGGGGATTATCCTGCAGGTGTTATCTGGCAACAGGCAAAAGATT
ATTGTCAGTGGTTAGGTATAAAATCCGGTAAAAAAATTGATTTGCCGACAGAGGCACAATGGGAGTTTGCAGCAAGATCC
AGAGGTCAGTATCTTCCGTTTGCTACTAACAATGGTGAGTTTTCACCAGGAAAAAATGTCCCAAGCCAGGATGAACTGAA
TAAATACACTGACGGGATGGGGCTTCCCATTTATCCAGTAGGTAAATACCCATCAAATCCCTTAGGGCTGTATGATATGG
GATTGAGTGGTTCTGAATGGACCAATGACTGGTATGCAGCAGATTATTACTCCAACTCTCCGGTAAAGAATCCTCAGGGA
CCAGAGCAAGGGACCGAGAAAGTGTTGCGTGGGAATGTTGGCGGCGACAGACAGTACGCATTGACTATGTTTAGACAATC
TGCTTCACCACTCCCAGAAGAAGTTGATGGTGACTATGAAAAATATGGTGTTGGTCCGCAGTATGTTTTCCGTTGCGTCA
TCAATAAATAA

Upstream 100 bases:

>100_bases
ACCCATACCTGACATCCTGATGTCAGAATATCTTGCCATGATCGACGACCAGCACCCGACGGGTACAATGACTGCCTGAT
ACAATGGCTGAGGTGATAAG

Downstream 100 bases:

>100_bases
TGTCGTTTGGTGGTGACATATATCATTTTAACCGGAGCAACAGTGTTGAATGAATGTTCCAATAAACCGGAGAGACTATT
TAAACCTGTCCCGGATAGCC

Product: sulfatase modifying factor 1 precursor-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MRKLIVVASVAAGLLTGCDQGNTTGSEKAAKALVDKSVSNMVPVQGGEFLMGDFGPLVGEKLPFSIQQDDKNLHKVILSD
FSISKYKVTNDDFNVYLKVTDKKNPPVDILAKRHPSLLKGDYPAGVIWQQAKDYCQWLGIKSGKKIDLPTEAQWEFAARS
RGQYLPFATNNGEFSPGKNVPSQDELNKYTDGMGLPIYPVGKYPSNPLGLYDMGLSGSEWTNDWYAADYYSNSPVKNPQG
PEQGTEKVLRGNVGGDRQYALTMFRQSASPLPEEVDGDYEKYGVGPQYVFRCVINK

Sequences:

>Translated_296_residues
MRKLIVVASVAAGLLTGCDQGNTTGSEKAAKALVDKSVSNMVPVQGGEFLMGDFGPLVGEKLPFSIQQDDKNLHKVILSD
FSISKYKVTNDDFNVYLKVTDKKNPPVDILAKRHPSLLKGDYPAGVIWQQAKDYCQWLGIKSGKKIDLPTEAQWEFAARS
RGQYLPFATNNGEFSPGKNVPSQDELNKYTDGMGLPIYPVGKYPSNPLGLYDMGLSGSEWTNDWYAADYYSNSPVKNPQG
PEQGTEKVLRGNVGGDRQYALTMFRQSASPLPEEVDGDYEKYGVGPQYVFRCVINK
>Mature_296_residues
MRKLIVVASVAAGLLTGCDQGNTTGSEKAAKALVDKSVSNMVPVQGGEFLMGDFGPLVGEKLPFSIQQDDKNLHKVILSD
FSISKYKVTNDDFNVYLKVTDKKNPPVDILAKRHPSLLKGDYPAGVIWQQAKDYCQWLGIKSGKKIDLPTEAQWEFAARS
RGQYLPFATNNGEFSPGKNVPSQDELNKYTDGMGLPIYPVGKYPSNPLGLYDMGLSGSEWTNDWYAADYYSNSPVKNPQG
PEQGTEKVLRGNVGGDRQYALTMFRQSASPLPEEVDGDYEKYGVGPQYVFRCVINK

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=234, Percent_Identity=29.9145299145299, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI38202250, Length=259, Percent_Identity=27.7992277992278, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 32640; Mature: 32640

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLIVVASVAAGLLTGCDQGNTTGSEKAAKALVDKSVSNMVPVQGGEFLMGDFGPLVGE
CCEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHCC
KLPFSIQQDDKNLHKVILSDFSISKYKVTNDDFNVYLKVTDKKNPPVDILAKRHPSLLKG
CCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCEEEEEEEECCCCCCHHHHHHCCCHHHCC
DYPAGVIWQQAKDYCQWLGIKSGKKIDLPTEAQWEFAARSRGQYLPFATNNGEFSPGKNV
CCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHCCCCCCCEECCCCCCCCCCCC
PSQDELNKYTDGMGLPIYPVGKYPSNPLGLYDMGLSGSEWTNDWYAADYYSNSPVKNPQG
CCHHHHHHHHCCCCCCEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCC
PEQGTEKVLRGNVGGDRQYALTMFRQSASPLPEEVDGDYEKYGVGPQYVFRCVINK
CHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHCCCHHHHCCCHHHHHEEECCC
>Mature Secondary Structure
MRKLIVVASVAAGLLTGCDQGNTTGSEKAAKALVDKSVSNMVPVQGGEFLMGDFGPLVGE
CCEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHCC
KLPFSIQQDDKNLHKVILSDFSISKYKVTNDDFNVYLKVTDKKNPPVDILAKRHPSLLKG
CCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCEEEEEEEECCCCCCHHHHHHCCCHHHCC
DYPAGVIWQQAKDYCQWLGIKSGKKIDLPTEAQWEFAARSRGQYLPFATNNGEFSPGKNV
CCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHCCCCCCCEECCCCCCCCCCCC
PSQDELNKYTDGMGLPIYPVGKYPSNPLGLYDMGLSGSEWTNDWYAADYYSNSPVKNPQG
CCHHHHHHHHCCCCCCEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCC
PEQGTEKVLRGNVGGDRQYALTMFRQSASPLPEEVDGDYEKYGVGPQYVFRCVINK
CHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHCCCHHHHCCCHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]