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The map label for this gene is pkn1 [H]

Identifier: 238895321

GI number: 238895321

Start: 3203967

End: 3204860

Strand: Reverse

Name: pkn1 [H]

Synonym: KP1_3380

Alternate gene names: 238895321

Gene position: 3204860-3203967 (Counterclockwise)

Preceding gene: 238895322

Following gene: 238895320

Centisome position: 61.06

GC content: 40.72

Gene sequence:

>894_bases
ATGAGAAAATTAATCGTAGTTGCTTCCGTTGCAGCCGGTTTACTGACCGGGTGCGACCAGAAGAGTACTGGCAAGCGTGA
AACCTTGTCTGAAGCGCTTGTTGCTAAGTCGCTTTCTAACATGGTTCCCGTTAAGGGCGGCGAGTTCTTAATGGGGGATT
TTGGCCCATTAGTCGGTCAAAAACTACCTTTCAGCATAAACCAGGATGATAAGGTATTACATAAGGTTGTATTAAGTGAT
TTTTCGATATCAAAGTTTAAAGTTACCAACGATGATTATAATAAATATCTGCAAATAACAGGGGTAAAAAAATCACCCAT
CCATATTTTTTTAAAAAATTATCCATCCTTGCAAAAAGGAGATTATTCTGTTGGTGTTACCTGGCAACAGGCAAAAGACT
ATTGTCAGTGGTTAGGTAAGGGGTCTGGTAAAAAGATTGATTTACCAACAGAGGCGCAATGGGAATATGCAGCAAGATCC
AGAGGTCAATACTTTCAGTTTCCAACAAATAATGGTGAGTATTTACCTGGAAAAAATGTTCCGGGTAAAGATGAATTAGA
TAAATATACAGATGGTTTTGGTTTCCCATTTTACCCAGTAGGCAAATATCCCCCAAACCCCCTGGGTCTGTATGATATGG
GGCTCAGTGGCTCTGAATGGACTAATGACTGGTATGCAGCAGATTATTACTCTCATTCACCGGTAAACGATCCCCAGGGA
CCTGCGCAGGGTACTAAAAAAGTCCTGCGTGGATATATTGGTGGCGACAGACAGTACGCTTTAACCATGTTCAGGCAATC
AAAATTGCCAGTTCCGAAGATCGATAAAGACGATGACTATGAAAAATATGGTGTTGGTCCGCAGTATGTATTTCGTTGTG
TCGTTAATAAATAA

Upstream 100 bases:

>100_bases
ACCTGTCCCGGATAGCCTGATGTCAGAATATCTTGCCATGATCGACGACCAGCACCCGACGGGGACAATGACTGCCTGAT
GCAATGGCTGAGGTGATAAG

Downstream 100 bases:

>100_bases
TGTGTGATGCCATCTCTTATTTTAACCGAATCAGAATGCTCAACGAATATTCGGCTGAACCGGATAGGATATTTAATCTA
TCCCGGATTTCCTGATGTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MRKLIVVASVAAGLLTGCDQKSTGKRETLSEALVAKSLSNMVPVKGGEFLMGDFGPLVGQKLPFSINQDDKVLHKVVLSD
FSISKFKVTNDDYNKYLQITGVKKSPIHIFLKNYPSLQKGDYSVGVTWQQAKDYCQWLGKGSGKKIDLPTEAQWEYAARS
RGQYFQFPTNNGEYLPGKNVPGKDELDKYTDGFGFPFYPVGKYPPNPLGLYDMGLSGSEWTNDWYAADYYSHSPVNDPQG
PAQGTKKVLRGYIGGDRQYALTMFRQSKLPVPKIDKDDDYEKYGVGPQYVFRCVVNK

Sequences:

>Translated_297_residues
MRKLIVVASVAAGLLTGCDQKSTGKRETLSEALVAKSLSNMVPVKGGEFLMGDFGPLVGQKLPFSINQDDKVLHKVVLSD
FSISKFKVTNDDYNKYLQITGVKKSPIHIFLKNYPSLQKGDYSVGVTWQQAKDYCQWLGKGSGKKIDLPTEAQWEYAARS
RGQYFQFPTNNGEYLPGKNVPGKDELDKYTDGFGFPFYPVGKYPPNPLGLYDMGLSGSEWTNDWYAADYYSHSPVNDPQG
PAQGTKKVLRGYIGGDRQYALTMFRQSKLPVPKIDKDDDYEKYGVGPQYVFRCVVNK
>Mature_297_residues
MRKLIVVASVAAGLLTGCDQKSTGKRETLSEALVAKSLSNMVPVKGGEFLMGDFGPLVGQKLPFSINQDDKVLHKVVLSD
FSISKFKVTNDDYNKYLQITGVKKSPIHIFLKNYPSLQKGDYSVGVTWQQAKDYCQWLGKGSGKKIDLPTEAQWEYAARS
RGQYFQFPTNNGEYLPGKNVPGKDELDKYTDGFGFPFYPVGKYPPNPLGLYDMGLSGSEWTNDWYAADYYSHSPVNDPQG
PAQGTKKVLRGYIGGDRQYALTMFRQSKLPVPKIDKDDDYEKYGVGPQYVFRCVVNK

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=234, Percent_Identity=30.3418803418803, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI38202250, Length=259, Percent_Identity=27.4131274131274, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 33228; Mature: 33228

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLIVVASVAAGLLTGCDQKSTGKRETLSEALVAKSLSNMVPVKGGEFLMGDFGPLVGQ
CCEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHCC
KLPFSINQDDKVLHKVVLSDFSISKFKVTNDDYNKYLQITGVKKSPIHIFLKNYPSLQKG
CCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCEEEEECCCCCCCCC
DYSVGVTWQQAKDYCQWLGKGSGKKIDLPTEAQWEYAARSRGQYFQFPTNNGEYLPGKNV
CEEEEEEHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCC
PGKDELDKYTDGFGFPFYPVGKYPPNPLGLYDMGLSGSEWTNDWYAADYYSHSPVNDPQG
CCHHHHHHHHCCCCCCCEECCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCCCCC
PAQGTKKVLRGYIGGDRQYALTMFRQSKLPVPKIDKDDDYEKYGVGPQYVFRCVVNK
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHEECCC
>Mature Secondary Structure
MRKLIVVASVAAGLLTGCDQKSTGKRETLSEALVAKSLSNMVPVKGGEFLMGDFGPLVGQ
CCEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHCC
KLPFSINQDDKVLHKVVLSDFSISKFKVTNDDYNKYLQITGVKKSPIHIFLKNYPSLQKG
CCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCEEEEECCCCCCCCC
DYSVGVTWQQAKDYCQWLGKGSGKKIDLPTEAQWEYAARSRGQYFQFPTNNGEYLPGKNV
CEEEEEEHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCC
PGKDELDKYTDGFGFPFYPVGKYPPNPLGLYDMGLSGSEWTNDWYAADYYSHSPVNDPQG
CCHHHHHHHHCCCCCCCEECCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCCCCC
PAQGTKKVLRGYIGGDRQYALTMFRQSKLPVPKIDKDDDYEKYGVGPQYVFRCVVNK
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]