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The map label for this gene is ipk [H]

Identifier: 238895298

GI number: 238895298

Start: 3181499

End: 3182350

Strand: Direct

Name: ipk [H]

Synonym: KP1_3353

Alternate gene names: 238895298

Gene position: 3181499-3182350 (Clockwise)

Preceding gene: 238895297

Following gene: 238895299

Centisome position: 60.62

GC content: 59.86

Gene sequence:

>852_bases
ATGATGACCCGCTGGCCCTCTCCTGCAAAACTGAATCTGTTTTTATATATCACCGGCCAGCGGGCCGATGGTTACCATAC
CCTGCAAACGCTGTTTCAGTTTCTCGATTACGGCGATACGTTGACCATCGAACCGCGTAGTGACGGCCAACTGCGTCTGC
TGACGCCGGTGGCCGGCGTGCCGGACGAGGAGAATCTGATCGTTCGCGCCGCGCGTCTGCTGATGCATGCCGCCAGCGAA
AGCGATCGCCTGCCGGCGGGCAGCGGCGCCGATATCAGTATCGATAAGCGCCTGCCGATGGGCGGCGGCCTGGGCGGTGG
CTCCTCCAATGCCGCCACCGTGCTGGTGGCGCTCAACCATCTGTGGGGCTGCGGTCTCTCGGAAGATGAGCTGGCGACTC
TTGGCCTTCAGCTGGGGGCCGATGTGCCGGTTTTCGTGCGCGGCCATGCCGCCTTCGCCGAGGGGGTGGGTGAAATACTG
ACGCCGGTAGAACCCGAGGAAAAATGGTACCTGGTGGCCCACCCGGGGGTCAGTATTCCGACGCCGATCATTTTTCGCGA
TCCGGAGCTACCACGAAATACCCCGCGCCGGTCAATTAATACGTTATTAAATTGTGAATTCAGCAACGATTGCGAGCTTA
TCGCAAGAAAACGTTTTCGCGAGGTTGATGCCGCGCTTTCCTGGCTGTTAGAATATGCGCCGTCACGCCTGACCGGCACA
GGGGCCTGTGTGTTTGCTGAATTTAACACCGAATCCGCTGCCCGTCAGGTGCTGGACACTGCCCCGGCATGGCTAAATGG
CTTTGTGGCGCGCGGAGTTAACCTTTCGCCGCTCAAGCAGGCCCTGCTCTGA

Upstream 100 bases:

>100_bases
GCGGCTACACCAGCGATACCCAGCCAGCCCTACCGTCCAATGTCGAGCTGAACAATGGCGCTCAGCGCATCAAGCTGAAG
ATGGATAACTGGATCGTGAA

Downstream 100 bases:

>100_bases
ATCCTGCGCCGTGATGGCACATTGATAATGAGTCAGCCGGGGAAATTGAGTTACGGTGACAACGTCACCCTGTTCCAGAC
GTTGCATCGTGCTCTTTAAA

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MMTRWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLTIEPRSDGQLRLLTPVAGVPDEENLIVRAARLLMHAASE
SDRLPAGSGADISIDKRLPMGGGLGGGSSNAATVLVALNHLWGCGLSEDELATLGLQLGADVPVFVRGHAAFAEGVGEIL
TPVEPEEKWYLVAHPGVSIPTPIIFRDPELPRNTPRRSINTLLNCEFSNDCELIARKRFREVDAALSWLLEYAPSRLTGT
GACVFAEFNTESAARQVLDTAPAWLNGFVARGVNLSPLKQALL

Sequences:

>Translated_283_residues
MMTRWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLTIEPRSDGQLRLLTPVAGVPDEENLIVRAARLLMHAASE
SDRLPAGSGADISIDKRLPMGGGLGGGSSNAATVLVALNHLWGCGLSEDELATLGLQLGADVPVFVRGHAAFAEGVGEIL
TPVEPEEKWYLVAHPGVSIPTPIIFRDPELPRNTPRRSINTLLNCEFSNDCELIARKRFREVDAALSWLLEYAPSRLTGT
GACVFAEFNTESAARQVLDTAPAWLNGFVARGVNLSPLKQALL
>Mature_283_residues
MMTRWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLTIEPRSDGQLRLLTPVAGVPDEENLIVRAARLLMHAASE
SDRLPAGSGADISIDKRLPMGGGLGGGSSNAATVLVALNHLWGCGLSEDELATLGLQLGADVPVFVRGHAAFAEGVGEIL
TPVEPEEKWYLVAHPGVSIPTPIIFRDPELPRNTPRRSINTLLNCEFSNDCELIARKRFREVDAALSWLLEYAPSRLTGT
GACVFAEFNTESAARQVLDTAPAWLNGFVARGVNLSPLKQALL

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=283, Percent_Identity=84.8056537102474, Blast_Score=481, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 30675; Mature: 30675

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTRWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLTIEPRSDGQLRLLTPVAGV
CCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCC
PDEENLIVRAARLLMHAASESDRLPAGSGADISIDKRLPMGGGLGGGSSNAATVLVALNH
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHEEEHHH
LWGCGLSEDELATLGLQLGADVPVFVRGHAAFAEGVGEILTPVEPEEKWYLVAHPGVSIP
HHCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCC
TPIIFRDPELPRNTPRRSINTLLNCEFSNDCELIARKRFREVDAALSWLLEYAPSRLTGT
CCEEEECCCCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GACVFAEFNTESAARQVLDTAPAWLNGFVARGVNLSPLKQALL
CEEEEEECCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCC
>Mature Secondary Structure
MMTRWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLTIEPRSDGQLRLLTPVAGV
CCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCC
PDEENLIVRAARLLMHAASESDRLPAGSGADISIDKRLPMGGGLGGGSSNAATVLVALNH
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHEEEHHH
LWGCGLSEDELATLGLQLGADVPVFVRGHAAFAEGVGEILTPVEPEEKWYLVAHPGVSIP
HHCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCC
TPIIFRDPELPRNTPRRSINTLLNCEFSNDCELIARKRFREVDAALSWLLEYAPSRLTGT
CCEEEECCCCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GACVFAEFNTESAARQVLDTAPAWLNGFVARGVNLSPLKQALL
CEEEEEECCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA