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The map label for this gene is lrpA [H]

Identifier: 238895268

GI number: 238895268

Start: 3146451

End: 3146894

Strand: Reverse

Name: lrpA [H]

Synonym: KP1_3320

Alternate gene names: 238895268

Gene position: 3146894-3146451 (Counterclockwise)

Preceding gene: 238895270

Following gene: 238895265

Centisome position: 59.96

GC content: 59.91

Gene sequence:

>444_bases
ATGAATGACGTACTTGATGAAATTGACCGGGCGATCCTCACCTGTCTGACTCAGGATGCCAGAGTTTCGCTCAAGGTCCT
GAGCGCGCGAGTGGGGCTGACCTCGCCGAGCACCGCCGAGCGGGTGAAGCGCCTGGAGGAGCGGGGTGTCATTCAGGGCT
ATGGGGCGCGGGTAAATCTCGCCGCGCTGGGCTATAGCCTGCAGGCGCTGGTGCGGGTCCGTCCGCTGCCTGGGCTGCTG
CAGAAGGTGGATAAATATATCCAGGCGATGCCGGAATGTATTGAAAGTGACAAGGTGACCGGGGAAGATTGTTTTGTGAT
GCGTCTCGTGGTGCGCGATATTGCCCAGCTGGATACCCTGCTGGACGGTCTGGCGGAGTATGCGCAGTGTAACACCTCGG
TGGTGAAAAGCTCGCCGGTACAAAGGCGGTTGCCACCGCTGTGA

Upstream 100 bases:

>100_bases
CTCCACCATTTTTTAGTTATTGTGCGAAAAACCCTGACAGGGTGATATGGCTGAATTAAGGTAGAAGGGGGGAAATGCCT
TTTATAATTAGGTGAAATAT

Downstream 100 bases:

>100_bases
GTTTTTCCGGAGGCGGTGCTGCGCACCTGTTCGGGCTACCAGACGGCACCACCTGTCGCCTCGCTAAGCGAAGCGCGAGC
GATGAGACAGCAGAACAGGT

Product: putative regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MNDVLDEIDRAILTCLTQDARVSLKVLSARVGLTSPSTAERVKRLEERGVIQGYGARVNLAALGYSLQALVRVRPLPGLL
QKVDKYIQAMPECIESDKVTGEDCFVMRLVVRDIAQLDTLLDGLAEYAQCNTSVVKSSPVQRRLPPL

Sequences:

>Translated_147_residues
MNDVLDEIDRAILTCLTQDARVSLKVLSARVGLTSPSTAERVKRLEERGVIQGYGARVNLAALGYSLQALVRVRPLPGLL
QKVDKYIQAMPECIESDKVTGEDCFVMRLVVRDIAQLDTLLDGLAEYAQCNTSVVKSSPVQRRLPPL
>Mature_147_residues
MNDVLDEIDRAILTCLTQDARVSLKVLSARVGLTSPSTAERVKRLEERGVIQGYGARVNLAALGYSLQALVRVRPLPGLL
QKVDKYIQAMPECIESDKVTGEDCFVMRLVVRDIAQLDTLLDGLAEYAQCNTSVVKSSPVQRRLPPL

Specific function: Negative regulation of glyA transcription and kinB- dependent sporulation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=120, Percent_Identity=37.5, Blast_Score=71, Evalue=3e-14,
Organism=Escherichia coli, GI87081742, Length=118, Percent_Identity=31.3559322033898, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 16196; Mature: 16196

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDVLDEIDRAILTCLTQDARVSLKVLSARVGLTSPSTAERVKRLEERGVIQGYGARVNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEHH
AALGYSLQALVRVRPLPGLLQKVDKYIQAMPECIESDKVTGEDCFVMRLVVRDIAQLDTL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LDGLAEYAQCNTSVVKSSPVQRRLPPL
HHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNDVLDEIDRAILTCLTQDARVSLKVLSARVGLTSPSTAERVKRLEERGVIQGYGARVNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEHH
AALGYSLQALVRVRPLPGLLQKVDKYIQAMPECIESDKVTGEDCFVMRLVVRDIAQLDTL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LDGLAEYAQCNTSVVKSSPVQRRLPPL
HHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11902725; 9384377 [H]