Click here to switch to the map view.

The map label for this gene is tdk [H]

Identifier: 238895260

GI number: 238895260

Start: 3138996

End: 3139613

Strand: Reverse

Name: tdk [H]

Synonym: KP1_3312

Alternate gene names: 238895260

Gene position: 3139613-3138996 (Counterclockwise)

Preceding gene: 238895263

Following gene: 238895258

Centisome position: 59.82

GC content: 52.91

Gene sequence:

>618_bases
ATGGCACAACTTTATTTCTACTACTCTGCAATGAATGCAGGTAAGTCGACCGCTCTGTTGCAATCTTCGTACAATTACCA
GGAGCGGGGGATGCGTACCGTCGTTTATACCGCTGAGATTGATGACCGCTTTGGCGCCGGAAAAGTCAGTTCACGTATCG
GGCTCTCCTCGCCGGCCCGATTGTATAATCCACAGACCTCGTTATTTGACGATATTGCGGCGGAGCACCAGCTAAAGCCG
ATTCACTGCGTGCTGGTGGATGAAAGCCAGTTTCTGACGCGTGAACAGGTTCATGAGCTGTCCGAAGTTGTCGATACGCT
GGATATTCCGGTGCTTTGCTATGGGTTGCGGACGGACTTTCGTGGTGAGCTCTTTACCGGCAGCCAGTATTTACTGGCCT
GGTCAGATAAGCTGGTTGAGCTGAAAACGATCTGCTTCTGCGGCCGCAAGGCCAGCATGGTATTGCGCCTCGATCAGGAG
GGGCGTCCTTATAATGAGGGTGAGCAGGTCGTCATCGGCGGTAATGAGCGGTACGTATCGGTCTGCCGTAAGCATTATAA
AGAGGCGCTGAGCGTCGGTTCGTTAACCAAGGTACAAAACCAGCACCGTCCCTGCTGA

Upstream 100 bases:

>100_bases
CAGCTTCGCGACAATACCCCTGCTGAAAGCGCGGCTGTGCGCATAAAATATGGTACAATCGTCGCCGCGATAAAACACTT
TGATTGGGGTCACGCAGCCG

Downstream 100 bases:

>100_bases
TACCCTCAGAAGCTCGTACAGGCGCCTGTGGGCGCCTTTTTTATGTCTGCTATAGGTTGGCGTAGCTGGCGATAAAGAAT
GGCTGATAGCGGGGATAAAA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPARLYNPQTSLFDDIAAEHQLKP
IHCVLVDESQFLTREQVHELSEVVDTLDIPVLCYGLRTDFRGELFTGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQE
GRPYNEGEQVVIGGNERYVSVCRKHYKEALSVGSLTKVQNQHRPC

Sequences:

>Translated_205_residues
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPARLYNPQTSLFDDIAAEHQLKP
IHCVLVDESQFLTREQVHELSEVVDTLDIPVLCYGLRTDFRGELFTGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQE
GRPYNEGEQVVIGGNERYVSVCRKHYKEALSVGSLTKVQNQHRPC
>Mature_204_residues
AQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPARLYNPQTSLFDDIAAEHQLKPI
HCVLVDESQFLTREQVHELSEVVDTLDIPVLCYGLRTDFRGELFTGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQEG
RPYNEGEQVVIGGNERYVSVCRKHYKEALSVGSLTKVQNQHRPC

Specific function: Phosphorylates both thymidine and deoxyuridine [H]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=203, Percent_Identity=88.6699507389163, Blast_Score=377, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 23236; Mature: 23104

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPAR
CCEEEEEEEECCCCCCCEEHHCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHH
LYNPQTSLFDDIAAEHQLKPIHCVLVDESQFLTREQVHELSEVVDTLDIPVLCYGLRTDF
HCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
RGELFTGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQEGRPYNEGEQVVIGGNERYVS
CCEEECCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEECCCHHHHH
VCRKHYKEALSVGSLTKVQNQHRPC
HHHHHHHHHHCCCCHHHHHHCCCCC
>Mature Secondary Structure 
AQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPAR
CEEEEEEEECCCCCCCEEHHCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHH
LYNPQTSLFDDIAAEHQLKPIHCVLVDESQFLTREQVHELSEVVDTLDIPVLCYGLRTDF
HCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
RGELFTGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQEGRPYNEGEQVVIGGNERYVS
CCEEECCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEECCCHHHHH
VCRKHYKEALSVGSLTKVQNQHRPC
HHHHHHHHHHCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10222209; 11206551; 11258796 [H]