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The map label for this gene is pheS [H]

Identifier: 238895231

GI number: 238895231

Start: 3113723

End: 3114718

Strand: Reverse

Name: pheS [H]

Synonym: KP1_3280

Alternate gene names: 238895231

Gene position: 3114718-3113723 (Counterclockwise)

Preceding gene: 238895232

Following gene: 238895230

Centisome position: 59.34

GC content: 57.13

Gene sequence:

>996_bases
ATGAGGAAAACCATGTCACATCTCGCAGAGCTGGTTGCCAGTGCCAAGGCAGCCATTAACGAGGCATCAGATGTTGCTGC
GCTGGACAACGTCCGCGTGGAATACCTGGGTAAAAAAGGGCATCTGACCCTGCAAATGACCACCCTGCGTGAGCTGCCGC
CGGAAGAGCGTCCGGCAGCCGGTGCGGTCATCAACGAGGCGAAAGAGCAGGTGCAGCAGGCGCTGAACGCGCGTAAAGCT
GAACTGGAAGGCGCAGCGCTGAATGCGCGTCTGGCCGCAGAGACCATTGACGTCTCGCTGCCGGGTCGCCGCATTGAAAA
CGGCGGCCTGCATCCGGTTACTCGCACCATCGACCGTATTGAAAGTTTCTTCGGTGAGCTCGGCTTTACCGTGGCGACGG
GCCCGGAAATCGAAGACGATTACCACAACTTTGATGCGCTGAATATTCCGGGTCACCATCCGGCGCGCGCTGACCACGAC
ACTTTCTGGTTCGATGCCACTCGCCTGCTGCGTACGCAGACCTCCGGCGTGCAGATCCGCACCATGGAAAACCAGCAGCC
GCCTATCCGTATTATCGCGCCGGGCCGCGTCTATCGTAACGACTACGATCAGACCCACACCCCGATGTTCCATCAGATGG
AAGGTCTGATCGTTGATAAAAATATCAGCTTCACCAACCTGAAAGGGACGCTGCACGACTTCCTGAACAACTTCTTTGAA
GAAGATCTGCAGGTCCGCTTCCGTCCGTCCTACTTCCCGTTCACCGAACCGTCTGCGGAAGTTGACGTAATGGGTAAAAA
CGGCAAATGGCTGGAAGTGCTGGGCTGCGGGATGGTGCACCCGAACGTGCTGCGTAACGTGGGTATCGATCCGGAAGTCT
ACTCCGGCTTCGCCTTCGGCATGGGCATGGAGCGTCTGACCATGCTGCGCTATGGCGTCACCGATCTGCGCGCGTTCTTC
GAAAACGATCTGCGTTTCCTCAAACAGTTTAAATAA

Upstream 100 bases:

>100_bases
GAAACGGAAAACAGCGCCAGAAAGCCTCCCCTGTGGAGGCTTTTTTCGTATATGGATTCGGAATATTAATTTCACTATAA
CCGGTGTCTGCACCGACATA

Downstream 100 bases:

>100_bases
GGGCAGGACAGAACAATGAAATTCAGTGAACTGTGGTTACGCGAATGGGTTAACCCGGCGATCGACAGCGAAGCGCTTTC
CGATCAGATCACCATGGCGG

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRKTMSHLAELVASAKAAINEASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKA
ELEGAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHD
TFWFDATRLLRTQTSGVQIRTMENQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDKNISFTNLKGTLHDFLNNFFE
EDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRAFF
ENDLRFLKQFK

Sequences:

>Translated_331_residues
MRKTMSHLAELVASAKAAINEASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKA
ELEGAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHD
TFWFDATRLLRTQTSGVQIRTMENQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDKNISFTNLKGTLHDFLNNFFE
EDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRAFF
ENDLRFLKQFK
>Mature_331_residues
MRKTMSHLAELVASAKAAINEASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKA
ELEGAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHD
TFWFDATRLLRTQTSGVQIRTMENQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDKNISFTNLKGTLHDFLNNFFE
EDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRAFF
ENDLRFLKQFK

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=318, Percent_Identity=29.2452830188679, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI4758340, Length=259, Percent_Identity=33.2046332046332, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1788007, Length=327, Percent_Identity=96.9418960244648, Blast_Score=662, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566635, Length=283, Percent_Identity=31.8021201413428, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32563657, Length=260, Percent_Identity=30.3846153846154, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17508957, Length=260, Percent_Identity=30.3846153846154, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6321087, Length=267, Percent_Identity=30.3370786516854, Blast_Score=122, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6325304, Length=268, Percent_Identity=27.2388059701493, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18858079, Length=258, Percent_Identity=31.0077519379845, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17137424, Length=237, Percent_Identity=30.379746835443, Blast_Score=110, Evalue=9e-25,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 37316; Mature: 37316

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTMSHLAELVASAKAAINEASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEECCCCCEEEEEEHHHHCCCCCCCCC
GAVINEAKEQVQQALNARKAELEGAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEHEEEEEECCCCCCCCCCCCHHHHHHHHH
ESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIR
HHHHHHCCCEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
TMENQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDKNISFTNLKGTLHDFLNNFFE
EECCCCCCEEEEECCHHCCCCCCCCCCCHHHHHCCEEEECCCCEEECHHHHHHHHHHHHH
EDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFG
HHHEEEECCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHCCCCHHHHCCHHHH
MGMERLTMLRYGVTDLRAFFENDLRFLKQFK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKTMSHLAELVASAKAAINEASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEECCCCCEEEEEEHHHHCCCCCCCCC
GAVINEAKEQVQQALNARKAELEGAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEHEEEEEECCCCCCCCCCCCHHHHHHHHH
ESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIR
HHHHHHCCCEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
TMENQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDKNISFTNLKGTLHDFLNNFFE
EECCCCCCEEEEECCHHCCCCCCCCCCCHHHHHCCEEEECCCCEEECHHHHHHHHHHHHH
EDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFG
HHHEEEECCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHCCCCHHHHCCHHHH
MGMERLTMLRYGVTDLRAFFENDLRFLKQFK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA