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The map label for this gene is ppsA [H]

Identifier: 238895214

GI number: 238895214

Start: 3095981

End: 3098359

Strand: Reverse

Name: ppsA [H]

Synonym: KP1_3261

Alternate gene names: 238895214

Gene position: 3098359-3095981 (Counterclockwise)

Preceding gene: 238895219

Following gene: 238895212

Centisome position: 59.03

GC content: 59.52

Gene sequence:

>2379_bases
ATGTCCAACAATGGCTCGTCACCGCTGGTGCTTTGGTATAACCAACTCGGCATGAATGATGTAGACAGAGTTGGGGGCAA
AAATGCCTCCCTTGGTGAAATGATTACGAATCTGTCCGGTATGGGTGTTTCCGTACCTAACGGGTTTGCCACCACCGCTG
ATGCTTTCAATCAGTTCCTGGACCAAAGCGGTGTTAACCAGCGCATCTATGCGCTGCTGGATGAAACCGACATTGACGAC
GTTTCCGCATTAGCGAAAGCGGGCGCGCAGATCCGACAGTGGATCATCGATACCCCCTTCCAGAGCGAACTGGAAAACGC
GATTCGCGATGCTTATGACCTGCTGTCCGCCGATGACGCCGAGGCCTCATTCGCCGTGCGCTCTTCCGCCACCGCGGAAG
ATATGCCGGACGCCTCCTTCGCCGGGCAGCAAGAGACATTCCTCAACGTGCAGGGCTTTGACGCCGTGCTCGTTGCCGTG
AAGCACGTGTTTGCTTCGCTGTTTAACGATCGCGCAATCTCCTATCGCGTGCATCAGGGTTACGATCACCGCGGCGTGGC
GCTCTCCGCCGGGGTGCAGAGGATGGTCCGCTCCGATCTGGCCTCCTCCGGCGTCATGTTCTCCATCGATACCGAATCCG
GCTTTGACCAGGTGGTGTTTATCACCTCGGCGTGGGGTTTGGGCGAGATGGTGGTGCAGGGCGCGGTGAACCCGGACGAA
TTCTACGTCCACAAACCGACGCTGGCCGCTGGCCGTCCGGCGATCGTGCGCCGCACCATGGGGTCGAAAAAGATCCGTAT
GGTTTACGCGCCGACCCAGGAGCACGGTAAACAGGTGCGTATCGAAGATGTGCCGCAGGCGCAGCGCGATATTTTCTCGT
TAAGCAACGAGGAAGTGCAGGAGCTGGCGAAGCAGGCGGTGCAGATCGAGAAGCACTACGGCCGTCCGATGGATATCGAG
TGGGCGAAAGATGGCCACACCGGTAAGCTATTTATCGTCCAGGCGCGTCCTGAAACCGTGCGTTCCCGCGGCCAGGTGAT
GGAGCGTTATACCCTCCACGCTCAGGGGCAGATCATCGCCGAAGGGCGCGCCATCGGCCACCGCATTGGCGCCGGTCCGG
TCAAGGTGATCCACGATATCAGCGAGATGAATCGCATTGAGCCAGGCGACGTACTGGTTACCGATATGACCGACCCGGAC
TGGGAACCGATCATGAAAAAAGCCTCGGCGATTGTCACCAACCGCGGCGGGCGTACCTGTCACGCGGCGATTATCGCCCG
TGAGCTGGGGATCCCGGCGGTGGTCGGCTGCGGCGATGCTACCGATCGCATTCAGGAAAATCAGAATGTCACCGTCTCCT
GCGCCGAAGGCGACACCGGCTATGTCTACGCCGAGCTGCTCGACTTCAGCGTCAAGAGCTCCAGCGTCGGCGACATGCCG
GATCTGCCGCTGAAGGTGATGATGAACGTCGGCAACCCGGATCGCGCGTTCGACTTCGCCTGCCTGCCGAACGAAGGCGT
CGGTCTGGCGCGGCTGGAATTTATCATCAACCGTATGATTGGCGTTCATCCGCGCGCGCTGCTGGAGTTTGACGACCAGG
AGCCGGGCCTGCAGAACGAAATCCGCGAGCTGATGAAAGGCTACGATTCGCCGAGAGAGTTCTACGTTGGCCGCCTGACC
GAAGGGATCGCCACCCTCGGCGCCGCTTTCTATCCGAAACGGGTGATCGTGCGACTGTCGGACTTCAAATCGAACGAATA
CGCCAACCTGGTGGGCGGCGAGCGCTATGAGCCGGAAGAAGAGAACCCGATGCTCGGCTTCCGCGGCGCCGGACGCTACG
TTTCCGAAAGCTTCCGCGACTGCTTCGCCCTGGAGTGCGAAGCGATGAAGCGCGTGCGTAACGATATGGGACTGACCAAC
GTTGAAGTGATGGTCCCGTTCGTCCGTACCGTCGCCCAGGCGAAAGCGGTGGTCGAAGAGCTGGAGCGTCAGGGGCTGAA
GCGCGGCGAGAACGGGCTGAAGATCATTATGATGTGCGAGATCCCGTCGAACGCCTTGCTGGCGGAGCAGTTCCTCGAGT
ACTTCGACGGCTTCTCCATCGGTTCGAACGACATGACCCAACTGGCGCTCGGTCTGGACCGCGATTCCGGTGTGGTTTCT
GAGCTGTTTGATGAACGCAATGACGCGGTGAAAGCCCTGCTGTCGATGGCCATCCGCGCGGCGAAGAAACAGGGTAAATA
CGTCGGCATCTGCGGCCAGGGGCCGTCTGACCATGAGGATTTCGCCGCCTGGCTGATGGAAGAGGGGATTGATAGCTTGT
CCCTGAACCCGGATACCGTGGTACAAACCTGGTTAGGTCTGGCGGAACTGAAAAAATAA

Upstream 100 bases:

>100_bases
GATTCACCGTTTTTTTCAGCTTCATAAATATGTCAGGATAATCCTGCAGTCGATCGTGAAATTTTTTTCACTGGTATTAA
ATCACAAAAGGATTGTCTCG

Downstream 100 bases:

>100_bases
GTTCGCCCTGACAGGACCGATCCCCGGCAGCGATGCCGGGGATTTTTTTTACCGGTGTCAGGCTATCTGGTGTCGTGATG
CGCAGGGCAAAAAAAAGCCC

Product: phosphoenolpyruvate synthase

Products: NA

Alternate protein names: PEP synthase; Pyruvate, water dikinase [H]

Number of amino acids: Translated: 792; Mature: 791

Protein sequence:

>792_residues
MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVSVPNGFATTADAFNQFLDQSGVNQRIYALLDETDIDD
VSALAKAGAQIRQWIIDTPFQSELENAIRDAYDLLSADDAEASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAV
KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQVVFITSAWGLGEMVVQGAVNPDE
FYVHKPTLAAGRPAIVRRTMGSKKIRMVYAPTQEHGKQVRIEDVPQAQRDIFSLSNEEVQELAKQAVQIEKHYGRPMDIE
WAKDGHTGKLFIVQARPETVRSRGQVMERYTLHAQGQIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVLVTDMTDPD
WEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIQENQNVTVSCAEGDTGYVYAELLDFSVKSSSVGDMP
DLPLKVMMNVGNPDRAFDFACLPNEGVGLARLEFIINRMIGVHPRALLEFDDQEPGLQNEIRELMKGYDSPREFYVGRLT
EGIATLGAAFYPKRVIVRLSDFKSNEYANLVGGERYEPEEENPMLGFRGAGRYVSESFRDCFALECEAMKRVRNDMGLTN
VEVMVPFVRTVAQAKAVVEELERQGLKRGENGLKIIMMCEIPSNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVS
ELFDERNDAVKALLSMAIRAAKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLGLAELKK

Sequences:

>Translated_792_residues
MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVSVPNGFATTADAFNQFLDQSGVNQRIYALLDETDIDD
VSALAKAGAQIRQWIIDTPFQSELENAIRDAYDLLSADDAEASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAV
KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQVVFITSAWGLGEMVVQGAVNPDE
FYVHKPTLAAGRPAIVRRTMGSKKIRMVYAPTQEHGKQVRIEDVPQAQRDIFSLSNEEVQELAKQAVQIEKHYGRPMDIE
WAKDGHTGKLFIVQARPETVRSRGQVMERYTLHAQGQIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVLVTDMTDPD
WEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIQENQNVTVSCAEGDTGYVYAELLDFSVKSSSVGDMP
DLPLKVMMNVGNPDRAFDFACLPNEGVGLARLEFIINRMIGVHPRALLEFDDQEPGLQNEIRELMKGYDSPREFYVGRLT
EGIATLGAAFYPKRVIVRLSDFKSNEYANLVGGERYEPEEENPMLGFRGAGRYVSESFRDCFALECEAMKRVRNDMGLTN
VEVMVPFVRTVAQAKAVVEELERQGLKRGENGLKIIMMCEIPSNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVS
ELFDERNDAVKALLSMAIRAAKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLGLAELKK
>Mature_791_residues
SNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVSVPNGFATTADAFNQFLDQSGVNQRIYALLDETDIDDV
SALAKAGAQIRQWIIDTPFQSELENAIRDAYDLLSADDAEASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAVK
HVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQVVFITSAWGLGEMVVQGAVNPDEF
YVHKPTLAAGRPAIVRRTMGSKKIRMVYAPTQEHGKQVRIEDVPQAQRDIFSLSNEEVQELAKQAVQIEKHYGRPMDIEW
AKDGHTGKLFIVQARPETVRSRGQVMERYTLHAQGQIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVLVTDMTDPDW
EPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIQENQNVTVSCAEGDTGYVYAELLDFSVKSSSVGDMPD
LPLKVMMNVGNPDRAFDFACLPNEGVGLARLEFIINRMIGVHPRALLEFDDQEPGLQNEIRELMKGYDSPREFYVGRLTE
GIATLGAAFYPKRVIVRLSDFKSNEYANLVGGERYEPEEENPMLGFRGAGRYVSESFRDCFALECEAMKRVRNDMGLTNV
EVMVPFVRTVAQAKAVVEELERQGLKRGENGLKIIMMCEIPSNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSE
LFDERNDAVKALLSMAIRAAKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLGLAELKK

Specific function: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=792, Percent_Identity=95.4545454545455, Blast_Score=1572, Evalue=0.0,
Organism=Escherichia coli, GI1788756, Length=450, Percent_Identity=26.6666666666667, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788726, Length=192, Percent_Identity=33.8541666666667, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI48994992, Length=190, Percent_Identity=31.0526315789474, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1789193, Length=403, Percent_Identity=25.3101736972705, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564524, Length=331, Percent_Identity=25.6797583081571, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR006319
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.2 [H]

Molecular weight: Translated: 87062; Mature: 86930

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVSVPNGFATTADAFNQFL
CCCCCCCCEEEEECCCCCCHHHHCCCCCCHHHHHHHCCCCCCEECCCCCCHHHHHHHHHH
DQSGVNQRIYALLDETDIDDVSALAKAGAQIRQWIIDTPFQSELENAIRDAYDLLSADDA
HHCCCCCEEHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
EASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAVKHVFASLFNDRAISYRVHQG
CHHEEECCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECC
YDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQVVFITSAWGLGEMVVQGAVNPDE
CCCCCEEHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCHHHHHHHCCCCCCC
FYVHKPTLAAGRPAIVRRTMGSKKIRMVYAPTQEHGKQVRIEDVPQAQRDIFSLSNEEVQ
EEEECCCCCCCCHHHHHHHCCCCEEEEEECCCHHCCCEEEECCCCHHHHHHHHCCHHHHH
ELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQARPETVRSRGQVMERYTLHAQGQIIA
HHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEE
EGRAIGHRIGAGPVKVIHDISEMNRIEPGDVLVTDMTDPDWEPIMKKASAIVTNRGGRTC
CCHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCH
HAAIIARELGIPAVVGCGDATDRIQENQNVTVSCAEGDTGYVYAELLDFSVKSSSVGDMP
HHHHHHHHCCCCEEEECCCHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHCCCCCCCCCC
DLPLKVMMNVGNPDRAFDFACLPNEGVGLARLEFIINRMIGVHPRALLEFDDQEPGLQNE
CCCHHEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHEEECCCCCCCHHHH
IRELMKGYDSPREFYVGRLTEGIATLGAAFYPKRVIVRLSDFKSNEYANLVGGERYEPEE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCCCCCCCC
ENPMLGFRGAGRYVSESFRDCFALECEAMKRVRNDMGLTNVEVMVPFVRTVAQAKAVVEE
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LERQGLKRGENGLKIIMMCEIPSNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVS
HHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHH
ELFDERNDAVKALLSMAIRAAKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTV
HHHHCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHH
VQTWLGLAELKK
HHHHHHHHHHCC
>Mature Secondary Structure 
SNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVSVPNGFATTADAFNQFL
CCCCCCCEEEEECCCCCCHHHHCCCCCCHHHHHHHCCCCCCEECCCCCCHHHHHHHHHH
DQSGVNQRIYALLDETDIDDVSALAKAGAQIRQWIIDTPFQSELENAIRDAYDLLSADDA
HHCCCCCEEHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
EASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAVKHVFASLFNDRAISYRVHQG
CHHEEECCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECC
YDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQVVFITSAWGLGEMVVQGAVNPDE
CCCCCEEHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCHHHHHHHCCCCCCC
FYVHKPTLAAGRPAIVRRTMGSKKIRMVYAPTQEHGKQVRIEDVPQAQRDIFSLSNEEVQ
EEEECCCCCCCCHHHHHHHCCCCEEEEEECCCHHCCCEEEECCCCHHHHHHHHCCHHHHH
ELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQARPETVRSRGQVMERYTLHAQGQIIA
HHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEE
EGRAIGHRIGAGPVKVIHDISEMNRIEPGDVLVTDMTDPDWEPIMKKASAIVTNRGGRTC
CCHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCH
HAAIIARELGIPAVVGCGDATDRIQENQNVTVSCAEGDTGYVYAELLDFSVKSSSVGDMP
HHHHHHHHCCCCEEEECCCHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHCCCCCCCCCC
DLPLKVMMNVGNPDRAFDFACLPNEGVGLARLEFIINRMIGVHPRALLEFDDQEPGLQNE
CCCHHEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHEEECCCCCCCHHHH
IRELMKGYDSPREFYVGRLTEGIATLGAAFYPKRVIVRLSDFKSNEYANLVGGERYEPEE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCCCCCCCC
ENPMLGFRGAGRYVSESFRDCFALECEAMKRVRNDMGLTNVEVMVPFVRTVAQAKAVVEE
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LERQGLKRGENGLKIIMMCEIPSNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVS
HHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHH
ELFDERNDAVKALLSMAIRAAKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTV
HHHHCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHH
VQTWLGLAELKK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1310524; 9097039; 9278503 [H]