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The map label for this gene is yyaH [H]

Identifier: 238895061

GI number: 238895061

Start: 2943772

End: 2944155

Strand: Direct

Name: yyaH [H]

Synonym: KP1_3093

Alternate gene names: 238895061

Gene position: 2943772-2944155 (Clockwise)

Preceding gene: 238895059

Following gene: 238895062

Centisome position: 56.09

GC content: 60.42

Gene sequence:

>384_bases
ATGAAAATTGCCCATTTCGCCCTGTGGACCCAACAGCTCGACGTCCAGGCCCGCTTCTGGGTGGACTTCTTTGCCGCCAG
CATCAATGAAAAATACCTTAGCCAGACCAACCCCGGCTTTGCCTCCTATTTTGTTACTATCGACGACGAGGTGGTGATCG
AGCTGATGACCAAGCCTGGCCTGCAGCAGGCCTGCGCGGATAATAACCATACCGGCTGGGCGCATCTGGCCCTCTCGGTG
GGCGGGGCGGAACAGGTCGATGCCATCGCCCAACGCGCCGGGGCCGCCGGAATACTGATCTCGCCGCCGCGCACCACCGG
CGACGGCTATTATGAGGCGGTGATCGCCGATCCCGATGGCAACCTGATCGAAATCGTCGCATAG

Upstream 100 bases:

>100_bases
ATCGAGCATAACACAATCCTTAAATGATCAAAACCGAGCAGTAGCAAGCATGATCGTCTGCCCTGCTCTGGTTGTCAACG
TTCCTGCCCGGAGGTTTACC

Downstream 100 bases:

>100_bases
TCAGCAGAACGCCAGTATTCAGGAGGCATCCATGGCACATTACCGGATTATCGACACCGCATCCTGGCCCCGCCGGGACC
ATTTCACTTTTTACCGCCAA

Product: glyoxalase family protein

Products: glutathione; methylglyoxal

Alternate protein names: ORFF [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MKIAHFALWTQQLDVQARFWVDFFAASINEKYLSQTNPGFASYFVTIDDEVVIELMTKPGLQQACADNNHTGWAHLALSV
GGAEQVDAIAQRAGAAGILISPPRTTGDGYYEAVIADPDGNLIEIVA

Sequences:

>Translated_127_residues
MKIAHFALWTQQLDVQARFWVDFFAASINEKYLSQTNPGFASYFVTIDDEVVIELMTKPGLQQACADNNHTGWAHLALSV
GGAEQVDAIAQRAGAAGILISPPRTTGDGYYEAVIADPDGNLIEIVA
>Mature_127_residues
MKIAHFALWTQQLDVQARFWVDFFAASINEKYLSQTNPGFASYFVTIDDEVVIELMTKPGLQQACADNNHTGWAHLALSV
GGAEQVDAIAQRAGAAGILISPPRTTGDGYYEAVIADPDGNLIEIVA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 13741; Mature: 13741

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAHFALWTQQLDVQARFWVDFFAASINEKYLSQTNPGFASYFVTIDDEVVIELMTKPG
CCEEHHEEEHHHCCCCHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEECCCEEEEECCCCC
LQQACADNNHTGWAHLALSVGGAEQVDAIAQRAGAAGILISPPRTTGDGYYEAVIADPDG
HHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEEEECCCC
NLIEIVA
CEEEEEC
>Mature Secondary Structure
MKIAHFALWTQQLDVQARFWVDFFAASINEKYLSQTNPGFASYFVTIDDEVVIELMTKPG
CCEEHHEEEHHHCCCCHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEECCCEEEEECCCCC
LQQACADNNHTGWAHLALSVGGAEQVDAIAQRAGAAGILISPPRTTGDGYYEAVIADPDG
HHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEEEECCCC
NLIEIVA
CEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]