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The map label for this gene is glpR [H]

Identifier: 238895060

GI number: 238895060

Start: 2942910

End: 2943680

Strand: Reverse

Name: glpR [H]

Synonym: KP1_3092

Alternate gene names: 238895060

Gene position: 2943680-2942910 (Counterclockwise)

Preceding gene: 238895068

Following gene: 238895058

Centisome position: 56.09

GC content: 58.75

Gene sequence:

>771_bases
ATGCTCGATTATGCTGCTTTCCCTCAACAGCGACAAGCGCTGATTTGCCAGATCCTGCAGGAAAACGGCAGAGTGGTGTG
CGCGGAGCTGGCGGCGCGTCTTCAGGTGTCGGAGCATACCATCCGCCGCGATCTGCATGAGCTCAGCCGCGAGGGATTCT
GTAAAAAGGTGTATGGCGGGGCGGTGCTGAGTCTGCCGGAAGCGGGGGATTACAGTGAGCGGAAAGATAAAAACCGCGCG
ATAAAGCTCAGGATCGCGCAACAGTGTGCCCGGCTGGTGAAGCCCGGCGGCACTATTTTCATTGATACCGGGACCACCAA
TCTGGCGATGGCCGAGGCGCTGCCCACCGAGCTGGCGCTGACGGTGGTAACGAACTCGCCGGAGATCGCCGCGGTACTGG
TGAAAAAACCGCTGTATGACGTGGTGATCCTTGGCGGCCAGGTACAGCGAGCGAGCGGCGGTTGCGTCGGCGCCGCGGCG
GTGGCTCAGGTGCAGGGCATGTTATTCGACCAGGGGTTTATCGGCGGCTGCGCGATGGCGCCAGAGTCGGGCCTGACCGG
CTTTGACTATGCCGACTGCGAGTTCAAGAAAGCGGTCATTAAACAGTGCAGCGAGATTATTGTTGGTCTGACTTCGGATA
AAATTCCGGCAGCAGCGCGGTTTGTGGTGGCCGCCAGCAGCGATATCGATGTGCTGGTGGTGGAAGAGAATATCAGTCGC
GAATATCGCGTTGCCTTTCAGCAGCACGATATTCGCATCTATACCGTGTAA

Upstream 100 bases:

>100_bases
AATTTTCATGGTAAACCTCCGGGCAGGAACGTTGACAACCAGAGCAGGGCAGACGATCATGCTTGCTACTGCTCGGTTTT
GATCATTTAAGGATTGTGTT

Downstream 100 bases:

>100_bases
CCCGCTAGCGGGTGAGGGAGGTGGCGATAAGCCGCAGGCCCAGCGCCCCCAGCACCGTCGCGGTGGCGATGTCGATCCGC
CGCTTCAGCCGCAGGTAGAC

Product: putative DeoR-type transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MLDYAAFPQQRQALICQILQENGRVVCAELAARLQVSEHTIRRDLHELSREGFCKKVYGGAVLSLPEAGDYSERKDKNRA
IKLRIAQQCARLVKPGGTIFIDTGTTNLAMAEALPTELALTVVTNSPEIAAVLVKKPLYDVVILGGQVQRASGGCVGAAA
VAQVQGMLFDQGFIGGCAMAPESGLTGFDYADCEFKKAVIKQCSEIIVGLTSDKIPAAARFVVAASSDIDVLVVEENISR
EYRVAFQQHDIRIYTV

Sequences:

>Translated_256_residues
MLDYAAFPQQRQALICQILQENGRVVCAELAARLQVSEHTIRRDLHELSREGFCKKVYGGAVLSLPEAGDYSERKDKNRA
IKLRIAQQCARLVKPGGTIFIDTGTTNLAMAEALPTELALTVVTNSPEIAAVLVKKPLYDVVILGGQVQRASGGCVGAAA
VAQVQGMLFDQGFIGGCAMAPESGLTGFDYADCEFKKAVIKQCSEIIVGLTSDKIPAAARFVVAASSDIDVLVVEENISR
EYRVAFQQHDIRIYTV
>Mature_256_residues
MLDYAAFPQQRQALICQILQENGRVVCAELAARLQVSEHTIRRDLHELSREGFCKKVYGGAVLSLPEAGDYSERKDKNRA
IKLRIAQQCARLVKPGGTIFIDTGTTNLAMAEALPTELALTVVTNSPEIAAVLVKKPLYDVVILGGQVQRASGGCVGAAA
VAQVQGMLFDQGFIGGCAMAPESGLTGFDYADCEFKKAVIKQCSEIIVGLTSDKIPAAARFVVAASSDIDVLVVEENISR
EYRVAFQQHDIRIYTV

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=229, Percent_Identity=29.6943231441048, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787540, Length=247, Percent_Identity=31.1740890688259, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI226510968, Length=249, Percent_Identity=29.3172690763052, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789519, Length=233, Percent_Identity=27.4678111587983, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=28.6290322580645, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082344, Length=230, Percent_Identity=27.3913043478261, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788069, Length=235, Percent_Identity=27.2340425531915, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789170, Length=231, Percent_Identity=24.6753246753247, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787063, Length=150, Percent_Identity=32, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27664; Mature: 27664

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDYAAFPQQRQALICQILQENGRVVCAELAARLQVSEHTIRRDLHELSREGFCKKVYGG
CCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
AVLSLPEAGDYSERKDKNRAIKLRIAQQCARLVKPGGTIFIDTGTTNLAMAEALPTELAL
EEEECCCCCCCCHHHCCCCEEEHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCEEEE
TVVTNSPEIAAVLVKKPLYDVVILGGQVQRASGGCVGAAAVAQVQGMLFDQGFIGGCAMA
EEEECCCCEEEEEECCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
PESGLTGFDYADCEFKKAVIKQCSEIIVGLTSDKIPAAARFVVAASSDIDVLVVEENISR
CCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEEECCCCEEEEEECCCCC
EYRVAFQQHDIRIYTV
HHHEEEEECCEEEEEC
>Mature Secondary Structure
MLDYAAFPQQRQALICQILQENGRVVCAELAARLQVSEHTIRRDLHELSREGFCKKVYGG
CCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
AVLSLPEAGDYSERKDKNRAIKLRIAQQCARLVKPGGTIFIDTGTTNLAMAEALPTELAL
EEEECCCCCCCCHHHCCCCEEEHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCEEEE
TVVTNSPEIAAVLVKKPLYDVVILGGQVQRASGGCVGAAAVAQVQGMLFDQGFIGGCAMA
EEEECCCCEEEEEECCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
PESGLTGFDYADCEFKKAVIKQCSEIIVGLTSDKIPAAARFVVAASSDIDVLVVEENISR
CCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEEECCCCEEEEEECCCCC
EYRVAFQQHDIRIYTV
HHHEEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]