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The map label for this gene is rhtC [H]

Identifier: 238895059

GI number: 238895059

Start: 2942123

End: 2942905

Strand: Direct

Name: rhtC [H]

Synonym: KP1_3091

Alternate gene names: 238895059

Gene position: 2942123-2942905 (Clockwise)

Preceding gene: 238895057

Following gene: 238895061

Centisome position: 56.06

GC content: 61.3

Gene sequence:

>783_bases
TTGCGCAGAAAACGCGCGCCGCCAACGCCTGCTTCTCCCCGTCTAATACACACCTTTTTGACGTGCTTTCCTGAACCAGT
TTGCTACTCTGTCTGCTCCAACCGTCCACACGTTACCGACCGCCTGCCTGCGGCGGACATAACAGGAGTCGCTATGTTCC
TATCCAGCCTGATGGCCATTGCCGCGGTGCTGATCATGGGCGTGATCAGTCCCGGCCCAAGCTTTATTTTTGTCGCGCGC
AATGCCGTCGCTCGCTCGCGTCTGCACGGTATGGTGACCGCCCTCGGTAATGGCGCCGGTGCGGCCATTTTCTCCATTAT
GGCGATGCTGGGCCTGCAGAAGGTGCTCACCGCGGTGCCGGAGCTGTTTATTGGTTTGAAGGTGGCGGGCGGGCTCTATC
TGCTGTGGCTGGGCTATAAAATTTTTCGCGGGTCGGCGCAGCCGATGGATTTTTCCGCCAGCGGGATGGCCGGCAACCGC
TCTTTGCTGAAGACCTTCCGCGACGGGCTGTATACTCAGCTCAGCAATCCCAAAACGGCGCTGGTGTTCGCCTCAATTTT
TACCGCCCTGCTGCCGGCGCAGATCCCCACCGCCTTCTATTACATCGTGCCGCTGATGAGCTTTCTGATCGACGTCAGCT
GGTATTCGCTGGTGGCGCTGGTGCTGTCTGCCGACCGCCCGCGGCGCGTCTACCTGCGGCTGAAGCGGCGGATCGACATC
GCCACCGCGACGGTGCTGGGGGCGCTGGGCCTGCGGCTTATCGCCACCTCCCTCACCCGCTAG

Upstream 100 bases:

>100_bases
GCATAGCAGTGTCTCTTCTCTGTAGTTATTACGGTATGACAAAGATCACAGTTATTCAGTTTACCATCGATGACAAGAAT
GGGAATCGTTATTCAAACAG

Downstream 100 bases:

>100_bases
CGGGTTACACGGTATAGATGCGAATATCGTGCTGCTGAAAGGCAACGCGATATTCGCGACTGATATTCTCTTCCACCACC
AGCACATCGATATCGCTGCT

Product: amino acid exporter

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MRRKRAPPTPASPRLIHTFLTCFPEPVCYSVCSNRPHVTDRLPAADITGVAMFLSSLMAIAAVLIMGVISPGPSFIFVAR
NAVARSRLHGMVTALGNGAGAAIFSIMAMLGLQKVLTAVPELFIGLKVAGGLYLLWLGYKIFRGSAQPMDFSASGMAGNR
SLLKTFRDGLYTQLSNPKTALVFASIFTALLPAQIPTAFYYIVPLMSFLIDVSWYSLVALVLSADRPRRVYLRLKRRIDI
ATATVLGALGLRLIATSLTR

Sequences:

>Translated_260_residues
MRRKRAPPTPASPRLIHTFLTCFPEPVCYSVCSNRPHVTDRLPAADITGVAMFLSSLMAIAAVLIMGVISPGPSFIFVAR
NAVARSRLHGMVTALGNGAGAAIFSIMAMLGLQKVLTAVPELFIGLKVAGGLYLLWLGYKIFRGSAQPMDFSASGMAGNR
SLLKTFRDGLYTQLSNPKTALVFASIFTALLPAQIPTAFYYIVPLMSFLIDVSWYSLVALVLSADRPRRVYLRLKRRIDI
ATATVLGALGLRLIATSLTR
>Mature_260_residues
MRRKRAPPTPASPRLIHTFLTCFPEPVCYSVCSNRPHVTDRLPAADITGVAMFLSSLMAIAAVLIMGVISPGPSFIFVAR
NAVARSRLHGMVTALGNGAGAAIFSIMAMLGLQKVLTAVPELFIGLKVAGGLYLLWLGYKIFRGSAQPMDFSASGMAGNR
SLLKTFRDGLYTQLSNPKTALVFASIFTALLPAQIPTAFYYIVPLMSFLIDVSWYSLVALVLSADRPRRVYLRLKRRIDI
ATATVLGALGLRLIATSLTR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=201, Percent_Identity=32.3383084577114, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1786522, Length=207, Percent_Identity=28.9855072463768, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 28150; Mature: 28150

Theoretical pI: Translated: 11.30; Mature: 11.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]