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The map label for this gene is cynT [H]

Identifier: 238895058

GI number: 238895058

Start: 2941391

End: 2942026

Strand: Reverse

Name: cynT [H]

Synonym: KP1_3090

Alternate gene names: 238895058

Gene position: 2942026-2941391 (Counterclockwise)

Preceding gene: 238895060

Following gene: 238895054

Centisome position: 56.05

GC content: 55.66

Gene sequence:

>636_bases
ATGCAACATATCATTGAGGGCTTCCTCAACTTCCAGAAAGAGATCTTCCCCCAGCGTAAAGAACTCTTCCGCAGCCTGGC
CTCCAGCCAGAATCCCAAAGCGCTTTTCATCTCCTGTTCTGACAGCCGTCTGGTGCCGGAACTGGTTACCCAGCAGGAGC
CGGGACAGCTCTTTGTCATTCGTAATGCCGGGAATATCGTGCCGTCTTTCGGGCCGGAGCCGGGCGGCGTTTCCGCGACC
ATCGAATATGCCGTGGTTGCGCTGGGCGTGACGGATATCGTGATCTGCGGCCATTCCAACTGCGGCGCGATGAAAGCGAT
CGCCACCTGTCAGTGCCTTGAGCCGATGCCGGCGGTGTCTCACTGGCTACGCTATGCCGATGCCGCGAAAGCGGTGGTGG
AAAAGAAAACCTGGGCTAGCGAAACCGATAAGGTCAACGGCATGGTGCAGGAAAACGTCATCGCCCAACTGAATAACATC
AAGACCCATCCTTCGGTGGCGGTTGGTCTGCGCGACCATACCCTGCGCCTGCATGGCTGGTTCTACGACATCGAAACCGG
CGATATTCAGGCGCTGGATAAAAATACGAAATCCTTTGTTTCGCTGTCGGAAAATCCGGACGTCTTTTTCGAATAA

Upstream 100 bases:

>100_bases
GCAACTGTTTGAATAACGATTCCCATTCTTGTCATCGATGGTAAACTGAATAACTGTGATCTTTGTCATACCGTAATAAC
TACAGAGAAGAGACACTGCT

Downstream 100 bases:

>100_bases
AGTCTTTCCAGGGCACGGAGGCCCTGCAAACCCTCACCACGCCACGCAAATTTTGCCAAAATGGGCGCCGCTTTGCAGAC
AGCGGAAGGCCTCCGACTGA

Product: putative carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MQHIIEGFLNFQKEIFPQRKELFRSLASSQNPKALFISCSDSRLVPELVTQQEPGQLFVIRNAGNIVPSFGPEPGGVSAT
IEYAVVALGVTDIVICGHSNCGAMKAIATCQCLEPMPAVSHWLRYADAAKAVVEKKTWASETDKVNGMVQENVIAQLNNI
KTHPSVAVGLRDHTLRLHGWFYDIETGDIQALDKNTKSFVSLSENPDVFFE

Sequences:

>Translated_211_residues
MQHIIEGFLNFQKEIFPQRKELFRSLASSQNPKALFISCSDSRLVPELVTQQEPGQLFVIRNAGNIVPSFGPEPGGVSAT
IEYAVVALGVTDIVICGHSNCGAMKAIATCQCLEPMPAVSHWLRYADAAKAVVEKKTWASETDKVNGMVQENVIAQLNNI
KTHPSVAVGLRDHTLRLHGWFYDIETGDIQALDKNTKSFVSLSENPDVFFE
>Mature_211_residues
MQHIIEGFLNFQKEIFPQRKELFRSLASSQNPKALFISCSDSRLVPELVTQQEPGQLFVIRNAGNIVPSFGPEPGGVSAT
IEYAVVALGVTDIVICGHSNCGAMKAIATCQCLEPMPAVSHWLRYADAAKAVVEKKTWASETDKVNGMVQENVIAQLNNI
KTHPSVAVGLRDHTLRLHGWFYDIETGDIQALDKNTKSFVSLSENPDVFFE

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=208, Percent_Identity=65.8653846153846, Blast_Score=300, Evalue=6e-83,
Organism=Escherichia coli, GI1786318, Length=194, Percent_Identity=29.8969072164948, Blast_Score=84, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI115532990, Length=242, Percent_Identity=27.2727272727273, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI25147564, Length=244, Percent_Identity=29.0983606557377, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324292, Length=195, Percent_Identity=31.7948717948718, Blast_Score=98, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24645213, Length=248, Percent_Identity=25, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23245; Mature: 23245

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHIIEGFLNFQKEIFPQRKELFRSLASSQNPKALFISCSDSRLVPELVTQQEPGQLFVI
CHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEEE
RNAGNIVPSFGPEPGGVSATIEYAVVALGVTDIVICGHSNCGAMKAIATCQCLEPMPAVS
ECCCCCCCCCCCCCCCCCHHHHHHHEEECCEEEEEECCCCCCHHHHHHHHHHCCCCHHHH
HWLRYADAAKAVVEKKTWASETDKVNGMVQENVIAQLNNIKTHPSVAVGLRDHTLRLHGW
HHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEEE
FYDIETGDIQALDKNTKSFVSLSENPDVFFE
EEEECCCCEEECCCCCHHEEEECCCCCCEEC
>Mature Secondary Structure
MQHIIEGFLNFQKEIFPQRKELFRSLASSQNPKALFISCSDSRLVPELVTQQEPGQLFVI
CHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEEE
RNAGNIVPSFGPEPGGVSATIEYAVVALGVTDIVICGHSNCGAMKAIATCQCLEPMPAVS
ECCCCCCCCCCCCCCCCCHHHHHHHEEECCEEEEEECCCCCCHHHHHHHHHHCCCCHHHH
HWLRYADAAKAVVEKKTWASETDKVNGMVQENVIAQLNNIKTHPSVAVGLRDHTLRLHGW
HHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEEE
FYDIETGDIQALDKNTKSFVSLSENPDVFFE
EEEECCCCEEECCCCCHHEEEECCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]