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The map label for this gene is ribC [H]

Identifier: 238895044

GI number: 238895044

Start: 2929045

End: 2929680

Strand: Reverse

Name: ribC [H]

Synonym: KP1_3075

Alternate gene names: 238895044

Gene position: 2929680-2929045 (Counterclockwise)

Preceding gene: 238895047

Following gene: 238895041

Centisome position: 55.82

GC content: 52.36

Gene sequence:

>636_bases
ATGTTTACTGGTATTGTTCAGGGAACCGCGAAAGTGGTCTCCATTGATGATAAACCCAATTTTCGCACTCACGTGGTTGA
GTTACCGGCACATATGCTGGAGGGGCTGGAAACCGGCGCCTCGGTAGCCAACAACGGCTGCTGCCTGACGGTGACCGAAA
TCAACGGCGCACGCATCAGCTTCGATCTGATGAAAGAGACGCTGCGGATTACCAATCTTGGCGATATTCAGGTCGGCGAT
GAAGTGAACGTCGAGCGAGCGGCGAAATTTAGTGATGAAATCGGCGGGCATTTAATGTCCGGCCACATTATGACCACCGC
GGAAATCGTGAAGATTCTGACTTCCGAAAATAACCGTCAGATCTGGTTTAAAGTGCAGGATCCAACGCTGATGAAATACA
TCCTCTATAAAGGATTCATCGGTATTGACGGCATTAGTCTGACGGTGGGTGAGGTGACGGCGACCCGTTTCTGCGTGCAT
CTTATTCCGGAGACGCTGCAGCGGACCACCCTGGGAGCAAAAAAACTGGGCGATCGCGTCAATATTGAGATTGATCCGCA
GACCCAGGCGGTTGTCGATACGGTCGAACGCGTGCTGGCCGCGAAAGAGATGGCGGCTAAGGTCAATGAAGCCTGA

Upstream 100 bases:

>100_bases
CGAGGCACGAAGCGCGCTGGCAACCGCTTTGCCCTCCTGTTATTGTTCCCGATAGCGAAAGCGGTAATGATACCGTCATG
ATTTTCAACAGGAGCCAAAC

Downstream 100 bases:

>100_bases
AAAAAAATCCCCCGCCGATAAGCGGGGGAGTGTTATTTAACGGGCGACGCGCAGTCCATGTTCAATACCGCGCGAGAACA
CCACCTGCCAGAGCTGAATG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFTGIVQGTAKVVSIDDKPNFRTHVVELPAHMLEGLETGASVANNGCCLTVTEINGARISFDLMKETLRITNLGDIQVGD
EVNVERAAKFSDEIGGHLMSGHIMTTAEIVKILTSENNRQIWFKVQDPTLMKYILYKGFIGIDGISLTVGEVTATRFCVH
LIPETLQRTTLGAKKLGDRVNIEIDPQTQAVVDTVERVLAAKEMAAKVNEA

Sequences:

>Translated_211_residues
MFTGIVQGTAKVVSIDDKPNFRTHVVELPAHMLEGLETGASVANNGCCLTVTEINGARISFDLMKETLRITNLGDIQVGD
EVNVERAAKFSDEIGGHLMSGHIMTTAEIVKILTSENNRQIWFKVQDPTLMKYILYKGFIGIDGISLTVGEVTATRFCVH
LIPETLQRTTLGAKKLGDRVNIEIDPQTQAVVDTVERVLAAKEMAAKVNEA
>Mature_211_residues
MFTGIVQGTAKVVSIDDKPNFRTHVVELPAHMLEGLETGASVANNGCCLTVTEINGARISFDLMKETLRITNLGDIQVGD
EVNVERAAKFSDEIGGHLMSGHIMTTAEIVKILTSENNRQIWFKVQDPTLMKYILYKGFIGIDGISLTVGEVTATRFCVH
LIPETLQRTTLGAKKLGDRVNIEIDPQTQAVVDTVERVLAAKEMAAKVNEA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=205, Percent_Identity=89.7560975609756, Blast_Score=380, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6319733, Length=195, Percent_Identity=35.8974358974359, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23055; Mature: 23055

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVQGTAKVVSIDDKPNFRTHVVELPAHMLEGLETGASVANNGCCLTVTEINGARIS
CCCCEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHCCCCCEEEEEECCCCEEE
FDLMKETLRITNLGDIQVGDEVNVERAAKFSDEIGGHLMSGHIMTTAEIVKILTSENNRQ
HHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHCCCCCE
IWFKVQDPTLMKYILYKGFIGIDGISLTVGEVTATRFCVHLIPETLQRTTLGAKKLGDRV
EEEEECCCHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCHHHCCCEE
NIEIDPQTQAVVDTVERVLAAKEMAAKVNEA
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTGIVQGTAKVVSIDDKPNFRTHVVELPAHMLEGLETGASVANNGCCLTVTEINGARIS
CCCCEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHCCCCCEEEEEECCCCEEE
FDLMKETLRITNLGDIQVGDEVNVERAAKFSDEIGGHLMSGHIMTTAEIVKILTSENNRQ
HHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHCCCCCE
IWFKVQDPTLMKYILYKGFIGIDGISLTVGEVTATRFCVHLIPETLQRTTLGAKKLGDRV
EEEEECCCHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCHHHCCCEE
NIEIDPQTQAVVDTVERVLAAKEMAAKVNEA
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9022701; 9023191; 9097039; 9278503; 11377200 [H]