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The map label for this gene is tppB [H]

Identifier: 238895015

GI number: 238895015

Start: 2901534

End: 2903039

Strand: Direct

Name: tppB [H]

Synonym: KP1_3044

Alternate gene names: 238895015

Gene position: 2901534-2903039 (Clockwise)

Preceding gene: 238895013

Following gene: 238895016

Centisome position: 55.28

GC content: 56.04

Gene sequence:

>1506_bases
GTGTCTACTGCAAACAATAAACCAGCAGAAAGCGTGAGTCTGAACGCTTTCAAACAACCACGCGCGTTCTATCTCATTTT
CTCGATCGAGTTGTGGGAGCGTTTTGGTTACTACGGCCTGCAAGGGATCATGGCCGTTTACCTGGTAAAACAGCTGGGTA
TGTCGGAAGCGGATTCCATTACTCTGTTCTCCTCCTTTAGCGCGCTGGTTTATGGCCTCGTCGCCATTGGCGGCTGGCTG
GGTGATAAAGTGCTGGGTACCAAGCGTGTCATCATGCTGGGCGCTATCGTGCTGGCGATTGGCTATGCGCTGGTGGCCTG
GTCCGGCCATGACGCCGCTATCGTCTATATGGGTATGGCGACCATCGCCGTCGGTAACGGCCTGTTTAAAGCCAACCCGT
CCTCCCTGCTTTCTACCTGCTATGACAAAAACGACCCACGTCTGGACGGTGCATTTACCATGTACTACATGTCCATCAAC
ATCGGTTCGTTCTTCTCTATGCTGGCAACCCCGTGGCTGGCCGCACGTTTTGGCTGGAGCGTAGCGTTTGCCCTCAGCGT
GGTGGGGATGGTGATCACCATTATTAACTTCGCCTTCTGTCAGAAATGGGTTAAACAGTACGGCTCTAAACCGGACTTTG
CCCCGGTACACATGGGTAAACTGCTGGCGACCATCGCTGGCGTGGTGGTGCTGGTCGCTATCGCCACCTGGCTGCTGCAC
AACCAGGGTATCGCACGTATGGTGCTGGGCGTCGTCGCACTGGGTATCGTCGTGATTTTCGCCAAAGAAACCATAGGCCT
GAAAGGCGCTCCGCGTCGTAAAATGATCGTCGCTTTCCTGCTGATGGTAGAAGCGATTGTCTTCTTCGTGTTGTACAGCC
AGATGCCGACCTCGCTGAACTTCTTCGCCATCCGTAACGTGGAGCACTCGATCCTCGGTCTCGCCTTTGAACCGGAACAG
TATCAGGCGCTGAACCCGTTCTGGATCATGATTGGTAGCCCGATTCTGGCCGCCATCTACAACAAGATGGGCGACCGCCT
GCCGATGCCGCACAAATTTGCTATCGGTATGGTACTGTGCTCTGGCGCATTCCTCGTCCTGCCTTTAGGGGCGAAGTTCG
CCAGCGACGCCGGTATCGTCTCGGTCAACTGGCTGATTCTGAGCTACGCGCTGCAGTCTATCGGTGAACTGATGATTTCC
GGCCTCGGCCTGGCGATGGTCGCTCAGCTGGTTCCTCAGCGTCTGATGGGCTTCATCATGGGCAGCTGGTTCCTCACCAC
GGCAGGCGCGGCGATCATCGCTGGGAAAATCGCTAACCTGATGGCAGTCCCGGAGAATGTCACCGATCCGCTGGTGTCGC
TGGAAGTCTACGGTCACGTATTCCTGCAGATTGGTATCGTCACCGCGGTTATCGCCGCCCTGATGCTGCTGACCGCGCCG
AAACTGAATCGTATGACTCAGGACGACAGCGCGGACATTAAAGCACGCGAAACCGCGGCTGCCTGA

Upstream 100 bases:

>100_bases
TGCCGTTTTCCCTCCAAGAATAACTATAAAGGCGGCGGTCCAACGAGATTGCGCCCCGAACACCCCCCAGTAAATATGGG
ATGTAAAAAAAGAGGTATAT

Downstream 100 bases:

>100_bases
CGCCGCAGGGAAAACTAATTATTTTTAAGCCGCTAACGTTAGTTTAGCGGCTTTTTTTTTACCCCTGGCAGGACTAACAT
ACAGAAAACTGCAGCCACGA

Product: putative tripeptide transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MSTANNKPAESVSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWL
GDKVLGTKRVIMLGAIVLAIGYALVAWSGHDAAIVYMGMATIAVGNGLFKANPSSLLSTCYDKNDPRLDGAFTMYYMSIN
IGSFFSMLATPWLAARFGWSVAFALSVVGMVITIINFAFCQKWVKQYGSKPDFAPVHMGKLLATIAGVVVLVAIATWLLH
NQGIARMVLGVVALGIVVIFAKETIGLKGAPRRKMIVAFLLMVEAIVFFVLYSQMPTSLNFFAIRNVEHSILGLAFEPEQ
YQALNPFWIMIGSPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPLGAKFASDAGIVSVNWLILSYALQSIGELMIS
GLGLAMVAQLVPQRLMGFIMGSWFLTTAGAAIIAGKIANLMAVPENVTDPLVSLEVYGHVFLQIGIVTAVIAALMLLTAP
KLNRMTQDDSADIKARETAAA

Sequences:

>Translated_501_residues
MSTANNKPAESVSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWL
GDKVLGTKRVIMLGAIVLAIGYALVAWSGHDAAIVYMGMATIAVGNGLFKANPSSLLSTCYDKNDPRLDGAFTMYYMSIN
IGSFFSMLATPWLAARFGWSVAFALSVVGMVITIINFAFCQKWVKQYGSKPDFAPVHMGKLLATIAGVVVLVAIATWLLH
NQGIARMVLGVVALGIVVIFAKETIGLKGAPRRKMIVAFLLMVEAIVFFVLYSQMPTSLNFFAIRNVEHSILGLAFEPEQ
YQALNPFWIMIGSPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPLGAKFASDAGIVSVNWLILSYALQSIGELMIS
GLGLAMVAQLVPQRLMGFIMGSWFLTTAGAAIIAGKIANLMAVPENVTDPLVSLEVYGHVFLQIGIVTAVIAALMLLTAP
KLNRMTQDDSADIKARETAAA
>Mature_500_residues
STANNKPAESVSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLG
DKVLGTKRVIMLGAIVLAIGYALVAWSGHDAAIVYMGMATIAVGNGLFKANPSSLLSTCYDKNDPRLDGAFTMYYMSINI
GSFFSMLATPWLAARFGWSVAFALSVVGMVITIINFAFCQKWVKQYGSKPDFAPVHMGKLLATIAGVVVLVAIATWLLHN
QGIARMVLGVVALGIVVIFAKETIGLKGAPRRKMIVAFLLMVEAIVFFVLYSQMPTSLNFFAIRNVEHSILGLAFEPEQY
QALNPFWIMIGSPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPLGAKFASDAGIVSVNWLILSYALQSIGELMISG
LGLAMVAQLVPQRLMGFIMGSWFLTTAGAAIIAGKIANLMAVPENVTDPLVSLEVYGHVFLQIGIVTAVIAALMLLTAPK
LNRMTQDDSADIKARETAAA

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=387, Percent_Identity=24.8062015503876, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI226371746, Length=358, Percent_Identity=24.0223463687151, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1787922, Length=487, Percent_Identity=87.4743326488706, Blast_Score=875, Evalue=0.0,
Organism=Escherichia coli, GI1789911, Length=479, Percent_Identity=51.7745302713987, Blast_Score=506, Evalue=1e-144,
Organism=Escherichia coli, GI1790572, Length=474, Percent_Identity=29.957805907173, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1786927, Length=435, Percent_Identity=27.816091954023, Blast_Score=183, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17541704, Length=375, Percent_Identity=25.3333333333333, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71987453, Length=377, Percent_Identity=23.342175066313, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17569141, Length=371, Percent_Identity=24.5283018867925, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639585, Length=342, Percent_Identity=26.9005847953216, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24639583, Length=327, Percent_Identity=26.9113149847095, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639581, Length=327, Percent_Identity=26.9113149847095, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571098, Length=367, Percent_Identity=25.0681198910082, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28571102, Length=367, Percent_Identity=25.0681198910082, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28571100, Length=367, Percent_Identity=25.0681198910082, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 54080; Mature: 53949

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00778 HIS_ACID_PHOSPHAT_2 ; PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTANNKPAESVSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSI
CCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC
TLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGYALVAWSGHDAAIVYMGMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHH
TIAVGNGLFKANPSSLLSTCYDKNDPRLDGAFTMYYMSINIGSFFSMLATPWLAARFGWS
HHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHH
VAFALSVVGMVITIINFAFCQKWVKQYGSKPDFAPVHMGKLLATIAGVVVLVAIATWLLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NQGIARMVLGVVALGIVVIFAKETIGLKGAPRRKMIVAFLLMVEAIVFFVLYSQMPTSLN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FFAIRNVEHSILGLAFEPEQYQALNPFWIMIGSPILAAIYNKMGDRLPMPHKFAIGMVLC
EEEEECCCHHHEEEEECCHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHH
SGAFLVLPLGAKFASDAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLVPQRLMGFIM
CCCCEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GSWFLTTAGAAIIAGKIANLMAVPENVTDPLVSLEVYGHVFLQIGIVTAVIAALMLLTAP
HHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KLNRMTQDDSADIKARETAAA
HHHCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
STANNKPAESVSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSI
CCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC
TLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGYALVAWSGHDAAIVYMGMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHH
TIAVGNGLFKANPSSLLSTCYDKNDPRLDGAFTMYYMSINIGSFFSMLATPWLAARFGWS
HHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHH
VAFALSVVGMVITIINFAFCQKWVKQYGSKPDFAPVHMGKLLATIAGVVVLVAIATWLLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NQGIARMVLGVVALGIVVIFAKETIGLKGAPRRKMIVAFLLMVEAIVFFVLYSQMPTSLN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FFAIRNVEHSILGLAFEPEQYQALNPFWIMIGSPILAAIYNKMGDRLPMPHKFAIGMVLC
EEEEECCCHHHEEEEECCHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHH
SGAFLVLPLGAKFASDAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLVPQRLMGFIM
CCCCEEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GSWFLTTAGAAIIAGKIANLMAVPENVTDPLVSLEVYGHVFLQIGIVTAVIAALMLLTAP
HHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KLNRMTQDDSADIKARETAAA
HHHCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA