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The map label for this gene is bglC [H]

Identifier: 238895003

GI number: 238895003

Start: 2890978

End: 2892399

Strand: Direct

Name: bglC [H]

Synonym: KP1_3030

Alternate gene names: 238895003

Gene position: 2890978-2892399 (Clockwise)

Preceding gene: 238895002

Following gene: 238895004

Centisome position: 55.08

GC content: 57.31

Gene sequence:

>1422_bases
ATGTTCGCGCTTTTATTACACTCCCTTTATCATCAGACAGGGAGCTTTTTCATGGCCGCTTTTCCGCACAATTTCTTATG
GGGTGCCGCTACCGCAGCGTATCAGGTTGAGGGAGGACACGACGCCGACGGTAAAGGACCGTCAATCTGGGATATCTACT
CTCATCTGCCGGGTACCACCTTTGAAGGCACCACCGGCGATATTGCCGTCGACCACTATCACCGTTTTCGCGAAGACGTG
GCGTTAATGGCCGAGATGGGCCTGCAAAGCTATCGATTCTCCATCTCCTGGCCCCGCCTGCTGCCCGCCGGGCGCGGTAA
GGTGAATGAAGCGGGAGTCCAGTTTTACAGCGATCTGATCGACGAACTGCTGGCGCACAATATTGAGCCGATGATCACCC
TCTATCACTGGGATCTGCCGCAGGCCCTGCAGGATGAGGGCGGCTGGGAAGCGCGCACTACCGCCGAGGCCTTCGCCGAG
TACGCCCGCCTGTGCTATGCGCGCTTTGGTTCACGGGTGAAGCTGTGGGCTACCTTCAACGAAACCATTGTCTTCATTGG
GCACGGCTACATTAACGGCCTCCATCCCCCGGCGGTCCGCGATCCGGCGCGCGCCATTCAGGCCTGCCACCACGTATTTA
TCGCCCATGCGCTGGCGGTGAAGGCCTTTCGCGAGATGGCTGTGGCCGGCGAGATTGGCTTCGTCAACGTACTGCAACCG
CATACCCCGCTCACCGACAGCGAGGCGGACATTAAGGCCACCGAACTGGCTGACGCCATCCATACTCACTGGCTGTACGA
TCCGGTGCTGAAAGGCACCTATCCTGCCGACCTGCTGGCGCAGACCCAGGCGCTGTGGGGGGTACCTCGCTTTGCTCCAG
GCGACGACGCGCTGCTCCGTGACAACCGCTGCGACTTTATCGGTCTGAATTACTATCGCCGGGAAACGGTATCTGCCCAG
CCGCCTGAGATCGCTACCGGCGGCGAGCCTGGCGTGGAGGGATTATTCTATTTCGTGCGTAATCCCCAGAGTACATATAC
CGAATGGGGCTGGGAAATCTGGCCGCAGGGGCTAACTGACGGCATTATGATGATTAAGGCGCGCTATGGCGATATTCCGA
TATATATCACCGAGAATGGCCTCGGCGCGAAGGACCCGATTATTGACGGGGAAGTGGTCGACGACCCGCGGATTGATTAT
CTCAGCAGCCATATTGGCGCCCTCGAAAAAGCGCTGGCGCTGGGGGCAGATGTGCGCGGCTATTACCCCTGGTCATTTAT
CGATCTGCTGAGCTGGCTCAACGGCTACCAAAAGCAATATGGTTTTGTCTATGTCGATCACCAGCAAAATCTGGCGCGGA
AACGAAAGAAGAGTTTTTATTGGTACAAATCTGTTATTGCCAGTCACGGCGAACAGCGTTAA

Upstream 100 bases:

>100_bases
TCCCCACCGCCAGCGGATGTGGTGCACACGAAGTAGCTCCGCGTTAAAACAGTGACCCGCCTCGCAACTGTGCAACCGGT
TTCAGAAACCGGTTGCACAT

Downstream 100 bases:

>100_bases
TCTTCTCTTGCGGGCGCCATTCGGCGCCCGGTCTGATTTTAGAATATTCTTAAACTTCTCCCTGCTCTTCAAGGCTGGCT
TTGCCCCTTGTCATGGGTTT

Product: 6-phospho-beta-glucosidase A

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MFALLLHSLYHQTGSFFMAAFPHNFLWGAATAAYQVEGGHDADGKGPSIWDIYSHLPGTTFEGTTGDIAVDHYHRFREDV
ALMAEMGLQSYRFSISWPRLLPAGRGKVNEAGVQFYSDLIDELLAHNIEPMITLYHWDLPQALQDEGGWEARTTAEAFAE
YARLCYARFGSRVKLWATFNETIVFIGHGYINGLHPPAVRDPARAIQACHHVFIAHALAVKAFREMAVAGEIGFVNVLQP
HTPLTDSEADIKATELADAIHTHWLYDPVLKGTYPADLLAQTQALWGVPRFAPGDDALLRDNRCDFIGLNYYRRETVSAQ
PPEIATGGEPGVEGLFYFVRNPQSTYTEWGWEIWPQGLTDGIMMIKARYGDIPIYITENGLGAKDPIIDGEVVDDPRIDY
LSSHIGALEKALALGADVRGYYPWSFIDLLSWLNGYQKQYGFVYVDHQQNLARKRKKSFYWYKSVIASHGEQR

Sequences:

>Translated_473_residues
MFALLLHSLYHQTGSFFMAAFPHNFLWGAATAAYQVEGGHDADGKGPSIWDIYSHLPGTTFEGTTGDIAVDHYHRFREDV
ALMAEMGLQSYRFSISWPRLLPAGRGKVNEAGVQFYSDLIDELLAHNIEPMITLYHWDLPQALQDEGGWEARTTAEAFAE
YARLCYARFGSRVKLWATFNETIVFIGHGYINGLHPPAVRDPARAIQACHHVFIAHALAVKAFREMAVAGEIGFVNVLQP
HTPLTDSEADIKATELADAIHTHWLYDPVLKGTYPADLLAQTQALWGVPRFAPGDDALLRDNRCDFIGLNYYRRETVSAQ
PPEIATGGEPGVEGLFYFVRNPQSTYTEWGWEIWPQGLTDGIMMIKARYGDIPIYITENGLGAKDPIIDGEVVDDPRIDY
LSSHIGALEKALALGADVRGYYPWSFIDLLSWLNGYQKQYGFVYVDHQQNLARKRKKSFYWYKSVIASHGEQR
>Mature_473_residues
MFALLLHSLYHQTGSFFMAAFPHNFLWGAATAAYQVEGGHDADGKGPSIWDIYSHLPGTTFEGTTGDIAVDHYHRFREDV
ALMAEMGLQSYRFSISWPRLLPAGRGKVNEAGVQFYSDLIDELLAHNIEPMITLYHWDLPQALQDEGGWEARTTAEAFAE
YARLCYARFGSRVKLWATFNETIVFIGHGYINGLHPPAVRDPARAIQACHHVFIAHALAVKAFREMAVAGEIGFVNVLQP
HTPLTDSEADIKATELADAIHTHWLYDPVLKGTYPADLLAQTQALWGVPRFAPGDDALLRDNRCDFIGLNYYRRETVSAQ
PPEIATGGEPGVEGLFYFVRNPQSTYTEWGWEIWPQGLTDGIMMIKARYGDIPIYITENGLGAKDPIIDGEVVDDPRIDY
LSSHIGALEKALALGADVRGYYPWSFIDLLSWLNGYQKQYGFVYVDHQQNLARKRKKSFYWYKSVIASHGEQR

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=479, Percent_Identity=36.9519832985386, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI110681710, Length=479, Percent_Identity=34.6555323590814, Blast_Score=279, Evalue=5e-75,
Organism=Homo sapiens, GI13273313, Length=457, Percent_Identity=34.3544857768052, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI28376633, Length=472, Percent_Identity=29.8728813559322, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI24497614, Length=486, Percent_Identity=30.4526748971193, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI190360571, Length=98, Percent_Identity=52.0408163265306, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI2367174, Length=487, Percent_Identity=36.5503080082135, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI1789070, Length=483, Percent_Identity=37.2670807453416, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI2367270, Length=470, Percent_Identity=37.4468085106383, Blast_Score=262, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI17552856, Length=469, Percent_Identity=33.0490405117271, Blast_Score=248, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI17539390, Length=477, Percent_Identity=32.0754716981132, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI21356577, Length=453, Percent_Identity=33.3333333333333, Blast_Score=248, Evalue=7e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53226; Mature: 53226

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFALLLHSLYHQTGSFFMAAFPHNFLWGAATAAYQVEGGHDADGKGPSIWDIYSHLPGTT
CHHHHHHHHHHHCCCEEEEECCCCHHHHCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCC
FEGTTGDIAVDHYHRFREDVALMAEMGLQSYRFSISWPRLLPAGRGKVNEAGVQFYSDLI
CCCCCCCEEHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
DELLAHNIEPMITLYHWDLPQALQDEGGWEARTTAEAFAEYARLCYARFGSRVKLWATFN
HHHHHCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
ETIVFIGHGYINGLHPPAVRDPARAIQACHHVFIAHALAVKAFREMAVAGEIGFVNVLQP
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
HTPLTDSEADIKATELADAIHTHWLYDPVLKGTYPADLLAQTQALWGVPRFAPGDDALLR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEC
DNRCDFIGLNYYRRETVSAQPPEIATGGEPGVEGLFYFVRNPQSTYTEWGWEIWPQGLTD
CCCCCEEECCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHCCCEECCCCCCC
GIMMIKARYGDIPIYITENGLGAKDPIIDGEVVDDPRIDYLSSHIGALEKALALGADVRG
CEEEEEEECCCEEEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
YYPWSFIDLLSWLNGYQKQYGFVYVDHQQNLARKRKKSFYWYKSVIASHGEQR
CCCHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFALLLHSLYHQTGSFFMAAFPHNFLWGAATAAYQVEGGHDADGKGPSIWDIYSHLPGTT
CHHHHHHHHHHHCCCEEEEECCCCHHHHCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCC
FEGTTGDIAVDHYHRFREDVALMAEMGLQSYRFSISWPRLLPAGRGKVNEAGVQFYSDLI
CCCCCCCEEHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
DELLAHNIEPMITLYHWDLPQALQDEGGWEARTTAEAFAEYARLCYARFGSRVKLWATFN
HHHHHCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
ETIVFIGHGYINGLHPPAVRDPARAIQACHHVFIAHALAVKAFREMAVAGEIGFVNVLQP
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
HTPLTDSEADIKATELADAIHTHWLYDPVLKGTYPADLLAQTQALWGVPRFAPGDDALLR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEC
DNRCDFIGLNYYRRETVSAQPPEIATGGEPGVEGLFYFVRNPQSTYTEWGWEIWPQGLTD
CCCCCEEECCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHCCCEECCCCCCC
GIMMIKARYGDIPIYITENGLGAKDPIIDGEVVDDPRIDYLSSHIGALEKALALGADVRG
CEEEEEEECCCEEEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
YYPWSFIDLLSWLNGYQKQYGFVYVDHQQNLARKRKKSFYWYKSVIASHGEQR
CCCHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]