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The map label for this gene is add [H]

Identifier: 238895000

GI number: 238895000

Start: 2888508

End: 2889509

Strand: Direct

Name: add [H]

Synonym: KP1_3027

Alternate gene names: 238895000

Gene position: 2888508-2889509 (Clockwise)

Preceding gene: 238894999

Following gene: 238895002

Centisome position: 55.03

GC content: 62.87

Gene sequence:

>1002_bases
ATGATTGATTCCTCATTGCCATTAACCGACATTCATCGTCATCTTGACGGTAACATCCGGGCCCAAACCATCCTCGATCT
TGGCCGCGAATTTAATATCGCTCTTCCCGCAACCACCCTCGACACGCTGCGTCCTCATGTCCAGGTCACCAGCCTTGAGC
CCGATCTGGTTAGTTTCCTCGCCAAGCTCGACTGGGGGGTAAAGGTCCTGGCCTCGCTGGAAGCCTGTCGCCGCGTGGCG
TATGAGAACGTCGAAGACGCGGCGCGAAATGGCCTGCACTACGTTGAGCTGCGCTTCTCTCCCCGCTATATGGCGATGAC
CCACCGGCTGCCGGTCGACGGCGTGGTAGAGGCGGTAATTGCCGGGGTTCAAGAGGGATGCCGCGATTTCCAGGTCGACG
CCCGGCTGATCGGTATTCTGAGCCGCACCTTCGGCGAAGCCGCCTGTCAGGAAGAGCTGGCGGCGCTGCTCGCCCACCGC
GAGGGCATCACAGCCCTCGACCTCGCCGGCGATGAGCTCGGCTTCCCGGGTACGTTGTTCCGCAACCATTTTAACCAGGC
CCGCGACGCCGGGTGGCATATCACCGTCCACGCGGGCGAAGCGGCCGGCCCGGAAAGTATCTGGCAGGCCATTCGTGAGC
TGGGCGCGGAGCGCATCGGCCATGGGGTTAAAGCGGTAGAGGATCCAGCCCTGATGGACTACCTGGCCGAGCACCGCATC
GGGATTGAATCCTGCCTGACCTCGAACGTGCAAACCAGCACCGTGGCCTCCCTGGCCCAGCATCCGCTGAAGCAGTTCCT
TGAGCACGGCGTGCTGGCGAGCCTCAACACCGACGATCCGGCGGTCCAGGGTGTGGACATCATTCACGAGTATACCGTGG
CGGCGCCGGCGGCAGGGCTGAGCCGGGAGCAGATCCGTCAGGCGCAGATCAACGGCCTGACCCTGGCGTTCCTCGGCGAA
CAGGAAAAAGCCGCCCTCATTCAGCGGGTTGCCAAAGGCTGA

Upstream 100 bases:

>100_bases
CTGCCAGCTATTTGTATCGCATACATTTTTTCAATGCTTTTAAACAGTTATGTTCATGTTGTATAATGACGTGCACTTTA
ACTAAAAAAAGAGTGCGACC

Downstream 100 bases:

>100_bases
TAACCGGCCCGGCAGCCGTGCTGCCGGGCTCCTCCTCAGACCAGGCTGAGCGTGGCGCGATGTCTGGCCGACTCAATACC
CAACTCAATCAGGGTCATTA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIDSSLPLTDIHRHLDGNIRAQTILDLGREFNIALPATTLDTLRPHVQVTSLEPDLVSFLAKLDWGVKVLASLEACRRVA
YENVEDAARNGLHYVELRFSPRYMAMTHRLPVDGVVEAVIAGVQEGCRDFQVDARLIGILSRTFGEAACQEELAALLAHR
EGITALDLAGDELGFPGTLFRNHFNQARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDPALMDYLAEHRI
GIESCLTSNVQTSTVASLAQHPLKQFLEHGVLASLNTDDPAVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLTLAFLGE
QEKAALIQRVAKG

Sequences:

>Translated_333_residues
MIDSSLPLTDIHRHLDGNIRAQTILDLGREFNIALPATTLDTLRPHVQVTSLEPDLVSFLAKLDWGVKVLASLEACRRVA
YENVEDAARNGLHYVELRFSPRYMAMTHRLPVDGVVEAVIAGVQEGCRDFQVDARLIGILSRTFGEAACQEELAALLAHR
EGITALDLAGDELGFPGTLFRNHFNQARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDPALMDYLAEHRI
GIESCLTSNVQTSTVASLAQHPLKQFLEHGVLASLNTDDPAVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLTLAFLGE
QEKAALIQRVAKG
>Mature_333_residues
MIDSSLPLTDIHRHLDGNIRAQTILDLGREFNIALPATTLDTLRPHVQVTSLEPDLVSFLAKLDWGVKVLASLEACRRVA
YENVEDAARNGLHYVELRFSPRYMAMTHRLPVDGVVEAVIAGVQEGCRDFQVDARLIGILSRTFGEAACQEELAALLAHR
EGITALDLAGDELGFPGTLFRNHFNQARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDPALMDYLAEHRI
GIESCLTSNVQTSTVASLAQHPLKQFLEHGVLASLNTDDPAVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLTLAFLGE
QEKAALIQRVAKG

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=343, Percent_Identity=33.8192419825073, Blast_Score=166, Evalue=3e-41,
Organism=Escherichia coli, GI1787910, Length=331, Percent_Identity=81.570996978852, Blast_Score=561, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI17538512, Length=344, Percent_Identity=33.1395348837209, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32565969, Length=344, Percent_Identity=33.1395348837209, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324188, Length=335, Percent_Identity=27.7611940298507, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24645260, Length=330, Percent_Identity=26.0606060606061, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006650
- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36231; Mature: 36231

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSSLPLTDIHRHLDGNIRAQTILDLGREFNIALPATTLDTLRPHVQVTSLEPDLVSFL
CCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCEEECCHHHHHCCCCEEEECCCHHHHHHH
AKLDWGVKVLASLEACRRVAYENVEDAARNGLHYVELRFSPRYMAMTHRLPVDGVVEAVI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEEECCHHHHHHCCCCHHHHHHHHH
AGVQEGCRDFQVDARLIGILSRTFGEAACQEELAALLAHREGITALDLAGDELGFPGTLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHH
RNHFNQARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDPALMDYLAEHRI
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHCC
GIESCLTSNVQTSTVASLAQHPLKQFLEHGVLASLNTDDPAVQGVDIIHEYTVAAPAAGL
CHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCC
SREQIRQAQINGLTLAFLGEQEKAALIQRVAKG
CHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MIDSSLPLTDIHRHLDGNIRAQTILDLGREFNIALPATTLDTLRPHVQVTSLEPDLVSFL
CCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCEEECCHHHHHCCCCEEEECCCHHHHHHH
AKLDWGVKVLASLEACRRVAYENVEDAARNGLHYVELRFSPRYMAMTHRLPVDGVVEAVI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEEECCHHHHHHCCCCHHHHHHHHH
AGVQEGCRDFQVDARLIGILSRTFGEAACQEELAALLAHREGITALDLAGDELGFPGTLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHH
RNHFNQARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDPALMDYLAEHRI
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHCC
GIESCLTSNVQTSTVASLAQHPLKQFLEHGVLASLNTDDPAVQGVDIIHEYTVAAPAAGL
CHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCC
SREQIRQAQINGLTLAFLGEQEKAALIQRVAKG
CHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA