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The map label for this gene is ppa [H]

Identifier: 238894894

GI number: 238894894

Start: 2780162

End: 2780761

Strand: Reverse

Name: ppa [H]

Synonym: KP1_2914

Alternate gene names: 238894894

Gene position: 2780761-2780162 (Counterclockwise)

Preceding gene: 238894902

Following gene: 238894893

Centisome position: 52.98

GC content: 58.67

Gene sequence:

>600_bases
ATGCATCTGGTAAAAACCATCCTCACCGCCGGTCTGCTTTTGTCCGCCGCCGCCCAGGCCCACAATGTGCTGGAATTTCC
CCAGCCGGAAAACAACCCGGAAGAATTTTACGCCGTCACTGAGATCCCGACGGGCGGGATCGTTAAGTACGAAACCGATG
CTAAAACGGGGTTTATCGTCGCCGACCGCTTTCAGTCGATGCCGGTGGCCTACCCGGCGAACTACGGCTCGCTGACCCAG
TCGCTGGCCGGGGATGGCGACCCGCTGGACGTGGTGTTTTATACCCGCGCGCCGATGGCCCCGGGCACGCTGATTAAGCT
GCGGGCAATTGGTGTGCTGAAGATGGTAGACGGCGGTGAGAAAGACGACAAAATCATCGCCGTACCGGCCAGTAAAATTG
ACCCGACCTACGACGACATCAAGACCATCTCCGATCTGCCGAAAATAGAACAGCAGCGGCTGGAGGCCTTCTTCCGGGTC
TATAAAGAACTGCCGGAGGGGCGTAAAAAGGTCGAGCTGGCCGGCTTTAATGACGCCGCGGCCGCGAAGCAGGAGATCAA
ATCGGCCTGGGAGGCCTGGAAGGCGAAGAACCCGCAATAA

Upstream 100 bases:

>100_bases
TGGTAGGTAATAATATTGACGCTGAATGGTCATGTTTTTGTCATCACTCGAATCTATTGTTTTGCGCATCAATTTCTTAT
AACAACAGAGTGATACAACA

Downstream 100 bases:

>100_bases
TATTCATCGCGGGCGCTGTCCGCCGCCCGCGGCATTCGCTTTCACGATCCCTGTGGCGGCAAAATCACACGTCACACGTC
ACACGTCACACGACAACGCT

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MHLVKTILTAGLLLSAAAQAHNVLEFPQPENNPEEFYAVTEIPTGGIVKYETDAKTGFIVADRFQSMPVAYPANYGSLTQ
SLAGDGDPLDVVFYTRAPMAPGTLIKLRAIGVLKMVDGGEKDDKIIAVPASKIDPTYDDIKTISDLPKIEQQRLEAFFRV
YKELPEGRKKVELAGFNDAAAAKQEIKSAWEAWKAKNPQ

Sequences:

>Translated_199_residues
MHLVKTILTAGLLLSAAAQAHNVLEFPQPENNPEEFYAVTEIPTGGIVKYETDAKTGFIVADRFQSMPVAYPANYGSLTQ
SLAGDGDPLDVVFYTRAPMAPGTLIKLRAIGVLKMVDGGEKDDKIIAVPASKIDPTYDDIKTISDLPKIEQQRLEAFFRV
YKELPEGRKKVELAGFNDAAAAKQEIKSAWEAWKAKNPQ
>Mature_199_residues
MHLVKTILTAGLLLSAAAQAHNVLEFPQPENNPEEFYAVTEIPTGGIVKYETDAKTGFIVADRFQSMPVAYPANYGSLTQ
SLAGDGDPLDVVFYTRAPMAPGTLIKLRAIGVLKMVDGGEKDDKIIAVPASKIDPTYDDIKTISDLPKIEQQRLEAFFRV
YKELPEGRKKVELAGFNDAAAAKQEIKSAWEAWKAKNPQ

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Homo sapiens, GI29171702, Length=191, Percent_Identity=31.9371727748691, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI11056044, Length=191, Percent_Identity=31.413612565445, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI1790673, Length=177, Percent_Identity=42.3728813559322, Blast_Score=143, Evalue=7e-36,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 21809; Mature: 21809

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLVKTILTAGLLLSAAAQAHNVLEFPQPENNPEEFYAVTEIPTGGIVKYETDAKTGFIV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEECCCCCEEEEECCCCCCEEE
ADRFQSMPVAYPANYGSLTQSLAGDGDPLDVVFYTRAPMAPGTLIKLRAIGVLKMVDGGE
ECHHCCCCEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEHHHEEEEECCCCC
KDDKIIAVPASKIDPTYDDIKTISDLPKIEQQRLEAFFRVYKELPEGRKKVELAGFNDAA
CCCEEEEECCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHH
AAKQEIKSAWEAWKAKNPQ
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHLVKTILTAGLLLSAAAQAHNVLEFPQPENNPEEFYAVTEIPTGGIVKYETDAKTGFIV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEECCCCCEEEEECCCCCCEEE
ADRFQSMPVAYPANYGSLTQSLAGDGDPLDVVFYTRAPMAPGTLIKLRAIGVLKMVDGGE
ECHHCCCCEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEHHHEEEEECCCCC
KDDKIIAVPASKIDPTYDDIKTISDLPKIEQQRLEAFFRVYKELPEGRKKVELAGFNDAA
CCCEEEEECCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHH
AAKQEIKSAWEAWKAKNPQ
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA