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The map label for this gene is aes [C]

Identifier: 238894863

GI number: 238894863

Start: 2747839

End: 2748822

Strand: Reverse

Name: aes [C]

Synonym: KP1_2880

Alternate gene names: 238894863

Gene position: 2748822-2747839 (Counterclockwise)

Preceding gene: 238894864

Following gene: 238894862

Centisome position: 52.37

GC content: 51.12

Gene sequence:

>984_bases
GTGGCGAGTCGGGTATCGAATGGAAGTCTGGTTCTGAATCATTACTACATCACTACAGGATATTACCCTATGAACAAACA
CGTCGCTGCTATGCTGACGATGCTTATTATTCCGTCTGCTTTTGCGCAAACACCTTTAACAGACAGCAAAACTATCGTTA
TTAAACCTAGCGCTCTGGCCGTCGAGATGGTGCCTGATATTGCCTATTCATTTACGCAAAATATCATGGGACGACCGCTC
CAGTTAACGATGGATTTGCTCAAGCCTTATGCTGATAAACCGTTACCCGCAGTAGTATTTATTACCGGCGGCGGCTTTCT
CGATGCGCCCAAATCAAAATTCATCGGTCAGCGGGTCGATATTGCCCGGGCCGGTTACGTCGTCGCCAGCATTACCTATC
GGGTCGTACCCAATGTGACTTTCCCGGGCATGGTTGAAGATGCGAAAACGGCGGTCAGATTTTTACGCGCCAATGCTGAA
AAATTAGGCATCGATCCCAACCATATCGCTGTGATGGGCGAGTCGGCGGGTGGGTATTTAGCCGCCATGGTGGGTACCAC
CAGCGGCCATAAGGAATTCGACCAGGGAGAGTATTCAAATCAAAGCAGCGATGTGCAGGCGGTGGTTGATCTCTATGGCC
TGTCCGATCTGACGAAAGTCGGGGCTGACTTTTCCGCGGACATTCAAAAAGCGCATCAGTCACCGGCCATACCAGAGGCG
ATGCTGGTTAATGGTATTCCCTGGCAAGGCGGTGGCGCGATCTCCGCCTATCCCGAAAAGGCGAAACGGGCTAATCCCAT
CACCTGGATTTCGAATAAAACGCCGCCTTTTCTGCTAATGAACGGCGATGCCGACAATGTGGTTTCACCCAGCCAGTCAA
CGCTTTTACACGAGGCGCTGGTAGCGAAAAAAATACCGTCCACCCATTACGTGGTGAAAGGGGCGGATCACGCAGGTTTG
ATGTGGTATCAGCGGCTTTGTTGA

Upstream 100 bases:

>100_bases
TGCAACTGGATGTTTTACCGTATGTCGCGCCGATTCTCAGTTTGACGGTTACCTACGCAGGCGGGGACAAAGAGGTCACG
TTATTGCCGGAAGACTCGGA

Downstream 100 bases:

>100_bases
ATAAATCGAACTTTTGCTGAGTTGAAGGATCAGATCACGCATCCTCCCGACAACTCAGACCATTCCGTGGCAAAGCAAAA
GTTCAGAATCACCAACTGGT

Product: esterase/lipase

Products: alcohol; a carboxylate [C]

Alternate protein names: Lipase/Esterase; Alpha/Beta Hydrolase Fold-3 Domain Protein; Esterase/Lipase; Esterase; Lipase; Esterase/Lipase-Like Protein; Esterase/Lipase/Thioesterase; Alpha/Beta Hydrolase Fold-3 Domain-Containing Protein; Alpha/Beta Hydrolase; Alpha/Beta Hydrolase Fold Domain Protein; Alpha/Beta Hydrolase Fold Protein-3 Domain Protein; Pectinesterase; Esterase/Lipase-Like; Peptidase; Carboxylesterase Family Protein; Esterase LipC; Esterase LipO; Para-Nitrobenzyl Esterase; Lipoprotein; Lipolytic Protein; Membrane-Bound Esterase LipM; Triacylglycerol Lipase; Alpha/Beta Hydrolase Fold Protein; Esterase-Hydrolase; Alpha/Beta Hydrolase Fold Family Protein; Coagulation Factor 5/8 Type Domain Protein; Lipase/Esterase Protein; Carboxylesterase LipQ; Dienelactone Hydrolase; Esterase/Lipase/Thioesterase Family Protein; Alpha/Beta Hydrolase Family Protein; Carboxylesterase; Phospholipase/Carboxylesterase; Hydrolase; Peptidase S; Esterase LipM; Heroin Esterase

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MASRVSNGSLVLNHYYITTGYYPMNKHVAAMLTMLIIPSAFAQTPLTDSKTIVIKPSALAVEMVPDIAYSFTQNIMGRPL
QLTMDLLKPYADKPLPAVVFITGGGFLDAPKSKFIGQRVDIARAGYVVASITYRVVPNVTFPGMVEDAKTAVRFLRANAE
KLGIDPNHIAVMGESAGGYLAAMVGTTSGHKEFDQGEYSNQSSDVQAVVDLYGLSDLTKVGADFSADIQKAHQSPAIPEA
MLVNGIPWQGGGAISAYPEKAKRANPITWISNKTPPFLLMNGDADNVVSPSQSTLLHEALVAKKIPSTHYVVKGADHAGL
MWYQRLC

Sequences:

>Translated_327_residues
MASRVSNGSLVLNHYYITTGYYPMNKHVAAMLTMLIIPSAFAQTPLTDSKTIVIKPSALAVEMVPDIAYSFTQNIMGRPL
QLTMDLLKPYADKPLPAVVFITGGGFLDAPKSKFIGQRVDIARAGYVVASITYRVVPNVTFPGMVEDAKTAVRFLRANAE
KLGIDPNHIAVMGESAGGYLAAMVGTTSGHKEFDQGEYSNQSSDVQAVVDLYGLSDLTKVGADFSADIQKAHQSPAIPEA
MLVNGIPWQGGGAISAYPEKAKRANPITWISNKTPPFLLMNGDADNVVSPSQSTLLHEALVAKKIPSTHYVVKGADHAGL
MWYQRLC
>Mature_326_residues
ASRVSNGSLVLNHYYITTGYYPMNKHVAAMLTMLIIPSAFAQTPLTDSKTIVIKPSALAVEMVPDIAYSFTQNIMGRPLQ
LTMDLLKPYADKPLPAVVFITGGGFLDAPKSKFIGQRVDIARAGYVVASITYRVVPNVTFPGMVEDAKTAVRFLRANAEK
LGIDPNHIAVMGESAGGYLAAMVGTTSGHKEFDQGEYSNQSSDVQAVVDLYGLSDLTKVGADFSADIQKAHQSPAIPEAM
LVNGIPWQGGGAISAYPEKAKRANPITWISNKTPPFLLMNGDADNVVSPSQSTLLHEALVAKKIPSTHYVVKGADHAGLM
WYQRLC

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.- [C]

Molecular weight: Translated: 35189; Mature: 35058

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRVSNGSLVLNHYYITTGYYPMNKHVAAMLTMLIIPSAFAQTPLTDSKTIVIKPSALA
CCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEE
VEMVPDIAYSFTQNIMGRPLQLTMDLLKPYADKPLPAVVFITGGGFLDAPKSKFIGQRVD
EEHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHCCCHHH
IARAGYVVASITYRVVPNVTFPGMVEDAKTAVRFLRANAEKLGIDPNHIAVMGESAGGYL
HHHCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCEEEEEECCCCCEE
AAMVGTTSGHKEFDQGEYSNQSSDVQAVVDLYGLSDLTKVGADFSADIQKAHQSPAIPEA
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCHH
MLVNGIPWQGGGAISAYPEKAKRANPITWISNKTPPFLLMNGDADNVVSPSQSTLLHEAL
HHCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHH
VAKKIPSTHYVVKGADHAGLMWYQRLC
HHHCCCCCEEEEECCCCCHHHHHHHCC
>Mature Secondary Structure 
ASRVSNGSLVLNHYYITTGYYPMNKHVAAMLTMLIIPSAFAQTPLTDSKTIVIKPSALA
CCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEE
VEMVPDIAYSFTQNIMGRPLQLTMDLLKPYADKPLPAVVFITGGGFLDAPKSKFIGQRVD
EEHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHCCCHHH
IARAGYVVASITYRVVPNVTFPGMVEDAKTAVRFLRANAEKLGIDPNHIAVMGESAGGYL
HHHCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCEEEEEECCCCCEE
AAMVGTTSGHKEFDQGEYSNQSSDVQAVVDLYGLSDLTKVGADFSADIQKAHQSPAIPEA
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCHH
MLVNGIPWQGGGAISAYPEKAKRANPITWISNKTPPFLLMNGDADNVVSPSQSTLLHEAL
HHCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHH
VAKKIPSTHYVVKGADHAGLMWYQRLC
HHHCCCCCEEEEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA