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The map label for this gene is guaA [H]

Identifier: 238894850

GI number: 238894850

Start: 2734784

End: 2735521

Strand: Reverse

Name: guaA [H]

Synonym: KP1_2866

Alternate gene names: 238894850

Gene position: 2735521-2734784 (Counterclockwise)

Preceding gene: 238894851

Following gene: 238894842

Centisome position: 52.12

GC content: 65.72

Gene sequence:

>738_bases
GTGACACGTAACCGATTACTGCTGGTCCAGACCGGCACGCCGCCGACGGCCATTCGCCAGGCGCATGGCGATCTGCCGCG
CTGGTTTCGCACGCTGCTGGCGCCGTGGCAGACGCAGCTCACCACGGTGCGGGTGTTTGAAGATGAACCGCTGCCGGCGC
CGGATCGCCAGACCGTGGCGGTTCTCACCGGTTCGTGGGCAATGGTGTCCGATCGCCTGGCATGGAGCGAACGGACCGCC
GACTGGATCCGTCAGGCGGTGGCTATCGGCATGCCGCTGTTCGGCGTCTGCTATGGTCATCAACTGATGGCCCATGCGCT
GGGGGGCGAGGTGGCGTATCATCCTGGCGGGCGGGAAAGCGGCAGCCAAACCATTACGCTGTCGCCATGGGGTGTCGATG
ATCCGCTGCTGAGCGGCCTGCCGGCTACATTTCCTGCGCATCTGAGCCATTTGCAAACCGTGACTCGTCTGCCGGAAGGG
GCCACGGTGCTGGCCGCGTCCGCCCACGATCCCCACCAGATTGTGCGCTATGGGCCGCACGCGGTCTCTACGCAATTTCA
CCCGGAATTTACCGCGCCGATAGCCCGTTCGCTGATCCGCCACCGGGAGGCGGTGCTGCAGGCGGAAGGTATTGACGCGC
AGCGGTTACACGACGAGGTGCAGGAGAGCCCGCAGGGCGCGGCGATCCTTACGCGCTTCGTCAGCGCCTTTCTGACCCCG
GATGCCCCCGGCCATTAA

Upstream 100 bases:

>100_bases
ATTCCGCAGGCGCATCGTCCATAGTAATTGGTTATTTGTCCCATCGTCTTCCCGGCGGCATAGTGTTTTACGGGAACATG
ACCCGGAGCGAGGAGAAAAG

Downstream 100 bases:

>100_bases
TCCCCTGTCGTGAACAGCACCTGCCAGCGGCGACGCCGGCGGGTCATTTCGCGTGCCAGATCGGCCACCTCTGCAACGCG
CAGCGCGTCAACCGCCTGCG

Product: glutamine amidotransferase

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTRNRLLLVQTGTPPTAIRQAHGDLPRWFRTLLAPWQTQLTTVRVFEDEPLPAPDRQTVAVLTGSWAMVSDRLAWSERTA
DWIRQAVAIGMPLFGVCYGHQLMAHALGGEVAYHPGGRESGSQTITLSPWGVDDPLLSGLPATFPAHLSHLQTVTRLPEG
ATVLAASAHDPHQIVRYGPHAVSTQFHPEFTAPIARSLIRHREAVLQAEGIDAQRLHDEVQESPQGAAILTRFVSAFLTP
DAPGH

Sequences:

>Translated_245_residues
MTRNRLLLVQTGTPPTAIRQAHGDLPRWFRTLLAPWQTQLTTVRVFEDEPLPAPDRQTVAVLTGSWAMVSDRLAWSERTA
DWIRQAVAIGMPLFGVCYGHQLMAHALGGEVAYHPGGRESGSQTITLSPWGVDDPLLSGLPATFPAHLSHLQTVTRLPEG
ATVLAASAHDPHQIVRYGPHAVSTQFHPEFTAPIARSLIRHREAVLQAEGIDAQRLHDEVQESPQGAAILTRFVSAFLTP
DAPGH
>Mature_244_residues
TRNRLLLVQTGTPPTAIRQAHGDLPRWFRTLLAPWQTQLTTVRVFEDEPLPAPDRQTVAVLTGSWAMVSDRLAWSERTAD
WIRQAVAIGMPLFGVCYGHQLMAHALGGEVAYHPGGRESGSQTITLSPWGVDDPLLSGLPATFPAHLSHLQTVTRLPEGA
TVLAASAHDPHQIVRYGPHAVSTQFHPEFTAPIARSLIRHREAVLQAEGIDAQRLHDEVQESPQGAAILTRFVSAFLTPD
APGH

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GMP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR004739
- InterPro:   IPR022955
- InterPro:   IPR022310
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00117 GATase; PF00958 GMP_synt_C; PF02540 NAD_synthase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 26776; Mature: 26644

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRNRLLLVQTGTPPTAIRQAHGDLPRWFRTLLAPWQTQLTTVRVFEDEPLPAPDRQTVA
CCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHCCHHHCEEEEEEECCCCCCCCCCCEEE
VLTGSWAMVSDRLAWSERTADWIRQAVAIGMPLFGVCYGHQLMAHALGGEVAYHPGGRES
EEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCCC
GSQTITLSPWGVDDPLLSGLPATFPAHLSHLQTVTRLPEGATVLAASAHDPHQIVRYGPH
CCCEEEECCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCC
AVSTQFHPEFTAPIARSLIRHREAVLQAEGIDAQRLHDEVQESPQGAAILTRFVSAFLTP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
DAPGH
CCCCC
>Mature Secondary Structure 
TRNRLLLVQTGTPPTAIRQAHGDLPRWFRTLLAPWQTQLTTVRVFEDEPLPAPDRQTVA
CCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHCCHHHCEEEEEEECCCCCCCCCCCEEE
VLTGSWAMVSDRLAWSERTADWIRQAVAIGMPLFGVCYGHQLMAHALGGEVAYHPGGRES
EEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCCC
GSQTITLSPWGVDDPLLSGLPATFPAHLSHLQTVTRLPEGATVLAASAHDPHQIVRYGPH
CCCEEEECCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCC
AVSTQFHPEFTAPIARSLIRHREAVLQAEGIDAQRLHDEVQESPQGAAILTRFVSAFLTP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
DAPGH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA