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The map label for this gene is 238894843

Identifier: 238894843

GI number: 238894843

Start: 2728135

End: 2729154

Strand: Direct

Name: 238894843

Synonym: KP1_2860

Alternate gene names: NA

Gene position: 2728135-2729154 (Clockwise)

Preceding gene: 238894838

Following gene: 238894844

Centisome position: 51.98

GC content: 58.14

Gene sequence:

>1020_bases
ATGGCGATTTTTGATGGTCACAATGACCTGCTGCTGAATCTCTGGCTTCACCATCGCGCGGATCCGGTGAGCGCCTTCTT
TGCCGGGATAGAGAACGGCCATCTCGACTATCCGCGCATGCTGCAAGGCGGATTTGCCGGCGGGCTATTCGCGCTATTCG
TGCCACCGCAGGAATATATTGCCCGTATGACGCCGCAATACGCCAGCCAACGATGGGATCCGATCGATATCCTCTGGCAG
CAACTGGCCATCCTGAAGCAACTTATCGCCCACTCCGCTGGACGCTTGAGATTGTGTCTGAGCGCGGCGGATATCGAACG
CTGCCGCGAGGATAAGGTACTGGCGATGGTGGCGCATATTGAGGGTGCCGGAGGTTTTGATGGCGAGGGCCGCGACCTGC
AGGCCTTTTATGCCGCCGGGGTCCGCAGCATTGGTCCGTTCTGGAACATTGCGAACCGCTTCGGCAGCGGCGTTAACGGT
TCGTTTCCCGGTAGCCCGGACACTGGGCCTGGACTGACAGCGGCAGGTATCGATCTGATTAAGCAGGTCAATGCCTTGAA
GATGCAGATGGACGTGTCTCATATGAATGAAAAAGCGTTCTGGGATACCGCCCATCACGCAACGTCACCGCTGGTGGCCA
CCCACTCCAATGCCCACGCCCTGTGCCCGCAGCCGCGCAATCTGACCGACCAGCAACTGCGGGCGATCCGCGACAGCGGC
GGCGTGGTGGGCGTCAATTTCGGCAATGCTTTCCTGCGCGCCGACGGCCGGCGCGATAGCGACACGCCCTTAACCACCAT
TGTCCGGCATATCGACTATCTTATTAACATAATGGGTGAGGATCATGTGGCCCTTGGCTCGGATTTTGACGGCATCACCC
TGCCGGACGAGCTGGGCGATGTGGCCGGCTTACCGCGGCTTATCAATACGTTGCGCGCTAGCGGCTATGATCAATTGGTG
CTGGATAAGCTGCTGTGGCGTAACTGGCTACGGGTATTAAAAAATGTTTGGCAACAATAG

Upstream 100 bases:

>100_bases
TTGGCAATTGTTGCGGGCATGTGAATTTATGCTTGCCCCGGGAGATAAATCCGTTACCGTGGCAGGCATTTTTCACCACT
TGAGAACGCAGGAACCCGCT

Downstream 100 bases:

>100_bases
GTTATATTGTAAACATAAAGTTAATTCCTTACAGATTCCGGGTTGATCTCTCTCCCGGTGAAGCGCAATATGCGGCAGCC
GTCACAGATCCACCATTATC

Product: proline dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MAIFDGHNDLLLNLWLHHRADPVSAFFAGIENGHLDYPRMLQGGFAGGLFALFVPPQEYIARMTPQYASQRWDPIDILWQ
QLAILKQLIAHSAGRLRLCLSAADIERCREDKVLAMVAHIEGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNG
SFPGSPDTGPGLTAAGIDLIKQVNALKMQMDVSHMNEKAFWDTAHHATSPLVATHSNAHALCPQPRNLTDQQLRAIRDSG
GVVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGEDHVALGSDFDGITLPDELGDVAGLPRLINTLRASGYDQLV
LDKLLWRNWLRVLKNVWQQ

Sequences:

>Translated_339_residues
MAIFDGHNDLLLNLWLHHRADPVSAFFAGIENGHLDYPRMLQGGFAGGLFALFVPPQEYIARMTPQYASQRWDPIDILWQ
QLAILKQLIAHSAGRLRLCLSAADIERCREDKVLAMVAHIEGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNG
SFPGSPDTGPGLTAAGIDLIKQVNALKMQMDVSHMNEKAFWDTAHHATSPLVATHSNAHALCPQPRNLTDQQLRAIRDSG
GVVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGEDHVALGSDFDGITLPDELGDVAGLPRLINTLRASGYDQLV
LDKLLWRNWLRVLKNVWQQ
>Mature_338_residues
AIFDGHNDLLLNLWLHHRADPVSAFFAGIENGHLDYPRMLQGGFAGGLFALFVPPQEYIARMTPQYASQRWDPIDILWQQ
LAILKQLIAHSAGRLRLCLSAADIERCREDKVLAMVAHIEGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNGS
FPGSPDTGPGLTAAGIDLIKQVNALKMQMDVSHMNEKAFWDTAHHATSPLVATHSNAHALCPQPRNLTDQQLRAIRDSGG
VVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGEDHVALGSDFDGITLPDELGDVAGLPRLINTLRASGYDQLVL
DKLLWRNWLRVLKNVWQQ

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=341, Percent_Identity=25.5131964809384, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4758190, Length=341, Percent_Identity=25.5131964809384, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI11641269, Length=341, Percent_Identity=25.2199413489736, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI193211608, Length=335, Percent_Identity=24.1791044776119, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI193211610, Length=335, Percent_Identity=24.1791044776119, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221475880, Length=346, Percent_Identity=28.6127167630058, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281362638, Length=346, Percent_Identity=26.5895953757225, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281362636, Length=346, Percent_Identity=26.5895953757225, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI161083233, Length=346, Percent_Identity=26.5895953757225, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 37333; Mature: 37202

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00869 RENAL_DIPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIFDGHNDLLLNLWLHHRADPVSAFFAGIENGHLDYPRMLQGGFAGGLFALFVPPQEYI
CEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEECCHHHH
ARMTPQYASQRWDPIDILWQQLAILKQLIAHSAGRLRLCLSAADIERCREDKVLAMVAHI
HHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCHHHEEHEEEE
EGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNGSFPGSPDTGPGLTAAGIDLI
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
KQVNALKMQMDVSHMNEKAFWDTAHHATSPLVATHSNAHALCPQPRNLTDQQLRAIRDSG
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCC
GVVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGEDHVALGSDFDGITLPDELGD
CEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHH
VAGLPRLINTLRASGYDQLVLDKLLWRNWLRVLKNVWQQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIFDGHNDLLLNLWLHHRADPVSAFFAGIENGHLDYPRMLQGGFAGGLFALFVPPQEYI
EEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEECCHHHH
ARMTPQYASQRWDPIDILWQQLAILKQLIAHSAGRLRLCLSAADIERCREDKVLAMVAHI
HHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCHHHEEHEEEE
EGAGGFDGEGRDLQAFYAAGVRSIGPFWNIANRFGSGVNGSFPGSPDTGPGLTAAGIDLI
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
KQVNALKMQMDVSHMNEKAFWDTAHHATSPLVATHSNAHALCPQPRNLTDQQLRAIRDSG
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCC
GVVGVNFGNAFLRADGRRDSDTPLTTIVRHIDYLINIMGEDHVALGSDFDGITLPDELGD
CEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHH
VAGLPRLINTLRASGYDQLVLDKLLWRNWLRVLKNVWQQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]