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The map label for this gene is iolE [H]

Identifier: 238894829

GI number: 238894829

Start: 2711633

End: 2712574

Strand: Direct

Name: iolE [H]

Synonym: KP1_2844

Alternate gene names: 238894829

Gene position: 2711633-2712574 (Clockwise)

Preceding gene: 238894828

Following gene: 238894830

Centisome position: 51.66

GC content: 62.31

Gene sequence:

>942_bases
ATGAAAAAGGAAGCCGACATGATACATCCTATCGCTAACGCCCCCTGCAGCTGGGGCGTCGATGACCCGAAAAACCCTAA
CCTCCCTGCCTGGGCTACCGTACTGAAGGAGGCGGCGCAGGCTGGCTATCGCAGCATTGAGCTCGGCCCCTGGGGTTATC
TCCCCACCGATCCGGCCAGCCTGCGCGCGGCGCTGGAGCAGCATCAGCTGTCGCTGGTCGCCGGCACGATCTTTGACGAT
CTGGTGAGCGAGGCCCATTTCCCCACCCTGGTGGCGCTGACCCATCAAATCTGCCGCAATCTGTCGCAGGTAGCCGCTGC
CGAACCGATCCCGGGCCGCCCTTTCCAGCCGCCCTATCTGGTGATTATCGACTTCGGCAACCCCGAACGGGCGCGCTTTG
CCGGGCGCGGCGCGCTGGCTCCGCGCCTCAATGACAAAGACTGGCAGCGCATGATGGAGCACATTATCGCCCTTAGCACC
CTCGCCTGGCAGGAGTACGGTGTGCGGGCGGTTATCCATCCGCACGCCGGGGGCAGCATTGAATTCGCGGATGAGATCGA
GCGGCTGGCCAACGATATCCCGCACGACGTCGCCGGGTTGTGTCTGGACACCGGACATCTCTATTACGCCGGGATGGATC
CGCTCGACTGGCTGGATCGCTATTACCACCGCCTGGACTATCTGCACTTCAAGGATGTCGACCCGCAGGTTTATCAGCGC
GCTATCCATGAAGGTATCGACTTCTTCACTGCCTGCGCCGAAGGGGTGATGTGCCCGCTCGGTAGCGGCGCCATTGACTA
TCCGGCTATCAAAGACTTTCTTGCCCGCCGGGGGTATCAGGGCTGGATAACCCTTGAACAAGAGCGCGACCCGCGCCATG
CCGCAGGCAGCCTGCAGGCGGTCACGGAAAGTCTGCGCTATCTGCGCGACGTCGGATTCTGA

Upstream 100 bases:

>100_bases
AAAAAATCCATCAATTAAAATCATGATGATTATCATAAAATCAAAATTCCATCATTGTTGACAATGAAATCTTTATTCAA
TACTCAGCGGCATCCCTTGT

Downstream 100 bases:

>100_bases
CAGGAGGCACGACATGATTAACGGTTTAAAACCTCTCGACCGCACCCTGCGCTGGGGCATGGTCGGCGGCGGCGACGGCA
GCCAGATCGGCTATATTCAC

Product: putative epimerase/isomerase

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKKEADMIHPIANAPCSWGVDDPKNPNLPAWATVLKEAAQAGYRSIELGPWGYLPTDPASLRAALEQHQLSLVAGTIFDD
LVSEAHFPTLVALTHQICRNLSQVAAAEPIPGRPFQPPYLVIIDFGNPERARFAGRGALAPRLNDKDWQRMMEHIIALST
LAWQEYGVRAVIHPHAGGSIEFADEIERLANDIPHDVAGLCLDTGHLYYAGMDPLDWLDRYYHRLDYLHFKDVDPQVYQR
AIHEGIDFFTACAEGVMCPLGSGAIDYPAIKDFLARRGYQGWITLEQERDPRHAAGSLQAVTESLRYLRDVGF

Sequences:

>Translated_313_residues
MKKEADMIHPIANAPCSWGVDDPKNPNLPAWATVLKEAAQAGYRSIELGPWGYLPTDPASLRAALEQHQLSLVAGTIFDD
LVSEAHFPTLVALTHQICRNLSQVAAAEPIPGRPFQPPYLVIIDFGNPERARFAGRGALAPRLNDKDWQRMMEHIIALST
LAWQEYGVRAVIHPHAGGSIEFADEIERLANDIPHDVAGLCLDTGHLYYAGMDPLDWLDRYYHRLDYLHFKDVDPQVYQR
AIHEGIDFFTACAEGVMCPLGSGAIDYPAIKDFLARRGYQGWITLEQERDPRHAAGSLQAVTESLRYLRDVGF
>Mature_313_residues
MKKEADMIHPIANAPCSWGVDDPKNPNLPAWATVLKEAAQAGYRSIELGPWGYLPTDPASLRAALEQHQLSLVAGTIFDD
LVSEAHFPTLVALTHQICRNLSQVAAAEPIPGRPFQPPYLVIIDFGNPERARFAGRGALAPRLNDKDWQRMMEHIIALST
LAWQEYGVRAVIHPHAGGSIEFADEIERLANDIPHDVAGLCLDTGHLYYAGMDPLDWLDRYYHRLDYLHFKDVDPQVYQR
AIHEGIDFFTACAEGVMCPLGSGAIDYPAIKDFLARRGYQGWITLEQERDPRHAAGSLQAVTESLRYLRDVGF

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 34951; Mature: 34951

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEADMIHPIANAPCSWGVDDPKNPNLPAWATVLKEAAQAGYRSIELGPWGYLPTDPAS
CCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHH
LRAALEQHQLSLVAGTIFDDLVSEAHFPTLVALTHQICRNLSQVAAAEPIPGRPFQPPYL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VIIDFGNPERARFAGRGALAPRLNDKDWQRMMEHIIALSTLAWQEYGVRAVIHPHAGGSI
EEEECCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
EFADEIERLANDIPHDVAGLCLDTGHLYYAGMDPLDWLDRYYHRLDYLHFKDVDPQVYQR
CHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
AIHEGIDFFTACAEGVMCPLGSGAIDYPAIKDFLARRGYQGWITLEQERDPRHAAGSLQA
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
VTESLRYLRDVGF
HHHHHHHHHHCCC
>Mature Secondary Structure
MKKEADMIHPIANAPCSWGVDDPKNPNLPAWATVLKEAAQAGYRSIELGPWGYLPTDPAS
CCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHH
LRAALEQHQLSLVAGTIFDDLVSEAHFPTLVALTHQICRNLSQVAAAEPIPGRPFQPPYL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VIIDFGNPERARFAGRGALAPRLNDKDWQRMMEHIIALSTLAWQEYGVRAVIHPHAGGSI
EEEECCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
EFADEIERLANDIPHDVAGLCLDTGHLYYAGMDPLDWLDRYYHRLDYLHFKDVDPQVYQR
CHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
AIHEGIDFFTACAEGVMCPLGSGAIDYPAIKDFLARRGYQGWITLEQERDPRHAAGSLQA
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
VTESLRYLRDVGF
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA