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The map label for this gene is nanT [H]

Identifier: 238894791

GI number: 238894791

Start: 2672157

End: 2673389

Strand: Reverse

Name: nanT [H]

Synonym: KP1_2801

Alternate gene names: 238894791

Gene position: 2673389-2672157 (Counterclockwise)

Preceding gene: 238894794

Following gene: 238894789

Centisome position: 50.94

GC content: 60.1

Gene sequence:

>1233_bases
ATGCACGGCTGGACCTCACGACAGCGTAATGCGGCGATAGCCAGTTTTTTAAGCTGGACGCTCGATGCTTTCGACTTTTT
CCTGTTAGTTTTTTTACTGAGCGATATCGCCCACTCGTTTCATGTCGACCTTGAGGAGGTCACTCTGGCGATTCTGCTGA
CTCTGGCCGTGCGGCCCGTCGGCGCGCTAATTTTCGGCAGGGCGGCGGAGAAGTTTGGTCGCAAACCAATCCTGATGCTC
AACATTGTGTTCTTCTCGGCTTTTGAGCTGCTCTCCGCCGCCGCGCCGTCGTTGATGCTGTTTTTCCTGCTGCGGGTGCT
GTACGGCGTGGCGATGGGCGGGATCTGGGGCGTGGCCTCTTCGCTGGCGATGGAGACGATCCCCGACCGCTCGCGCGGCC
TGATGTCCGGCCTGTTCCAGGCGGGATACCCCTTCGGCTATTTGCTGGCGGCCGTCGCCTACGGGCTGCTGTTTGAACAA
CTCGGCTGGCGCGGGATGTTTGTCATTGGCGCCGCGCCGGTGCTGCTGCTGCCGTTTATCTATTTCTGCGTCGAGGAGTC
TCCGGTTTGGCAGGCGGCCAGGCAGAATAAAGAGAGTACGGCCCTGCTGCCGGTACTGCGTAGCCACTGGAAGCTGTGCC
TGTACCTGGTGGTGCTGATGGCGGCTTTCAACTTCTTCTCCCACGGGACGCAGGATCTTTACCCGGTCTTTTTGAAAGTT
CAGCACGGCTTCGAGCCTAAAACGGTCAGCATCATCGCGGTCTGCTATAACATCGCCTCGATCATTGGTGGAGTGTTCTT
CGGTTCGCTGTCGGAGAAGATTGGCCGACGCAAAGCAATTATGATCGCCGCCCTGCTGGCGCTGCCGGTCATTCCACTGT
GGGCTTTCGCCAGCGGCTCGCTGGCGCTGGGGGCGGGGGCGTTCCTGATGCAGTTTATGGTCCAGGGGGCCTGGGGGGTG
ATCCCCACCTGGCTCAATGAACTGGTCCCGGCCAACACCCGGGCGGTGCTGCCCGGCTTCGTCTACCAGCTGGGTAATTT
GCTGGCTTCGGTGAATGCCACTCTCCAGGCATCAATCGCCCAGCATCATGGGCATAACTACGGCCTGGCAATGGCCCTGG
TGGCCGGGACGGTGGCGATTGTCATTACCGTCCTGACCTTTTTTGGTCGCGAAGGCCGGGTGATCCAATCCGCAGGAGCG
GGACATCACCAGCCGCTCTCCACCAGCCGTTAA

Upstream 100 bases:

>100_bases
CAACTTTCTATACAAACAATTTACACAAGCGGCGACCCCAGCTCGCTCTGCTGGACGCCGCGCACACTCCCGGCAATGCC
GTCGGGATAGGGATGACAAG

Downstream 100 bases:

>100_bases
CTTTTGTGACCGGGCGTGGCCAGGCGCCCGGTCGCATACATTAGTCACGCAGACGAATAGACGCCGCCTGGCGTTTCTCC
AGCGAGCAGATCCCAATCCC

Product: putative transporter

Products: NA

Alternate protein names: Sialic acid permease [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MHGWTSRQRNAAIASFLSWTLDAFDFFLLVFLLSDIAHSFHVDLEEVTLAILLTLAVRPVGALIFGRAAEKFGRKPILML
NIVFFSAFELLSAAAPSLMLFFLLRVLYGVAMGGIWGVASSLAMETIPDRSRGLMSGLFQAGYPFGYLLAAVAYGLLFEQ
LGWRGMFVIGAAPVLLLPFIYFCVEESPVWQAARQNKESTALLPVLRSHWKLCLYLVVLMAAFNFFSHGTQDLYPVFLKV
QHGFEPKTVSIIAVCYNIASIIGGVFFGSLSEKIGRRKAIMIAALLALPVIPLWAFASGSLALGAGAFLMQFMVQGAWGV
IPTWLNELVPANTRAVLPGFVYQLGNLLASVNATLQASIAQHHGHNYGLAMALVAGTVAIVITVLTFFGREGRVIQSAGA
GHHQPLSTSR

Sequences:

>Translated_410_residues
MHGWTSRQRNAAIASFLSWTLDAFDFFLLVFLLSDIAHSFHVDLEEVTLAILLTLAVRPVGALIFGRAAEKFGRKPILML
NIVFFSAFELLSAAAPSLMLFFLLRVLYGVAMGGIWGVASSLAMETIPDRSRGLMSGLFQAGYPFGYLLAAVAYGLLFEQ
LGWRGMFVIGAAPVLLLPFIYFCVEESPVWQAARQNKESTALLPVLRSHWKLCLYLVVLMAAFNFFSHGTQDLYPVFLKV
QHGFEPKTVSIIAVCYNIASIIGGVFFGSLSEKIGRRKAIMIAALLALPVIPLWAFASGSLALGAGAFLMQFMVQGAWGV
IPTWLNELVPANTRAVLPGFVYQLGNLLASVNATLQASIAQHHGHNYGLAMALVAGTVAIVITVLTFFGREGRVIQSAGA
GHHQPLSTSR
>Mature_410_residues
MHGWTSRQRNAAIASFLSWTLDAFDFFLLVFLLSDIAHSFHVDLEEVTLAILLTLAVRPVGALIFGRAAEKFGRKPILML
NIVFFSAFELLSAAAPSLMLFFLLRVLYGVAMGGIWGVASSLAMETIPDRSRGLMSGLFQAGYPFGYLLAAVAYGLLFEQ
LGWRGMFVIGAAPVLLLPFIYFCVEESPVWQAARQNKESTALLPVLRSHWKLCLYLVVLMAAFNFFSHGTQDLYPVFLKV
QHGFEPKTVSIIAVCYNIASIIGGVFFGSLSEKIGRRKAIMIAALLALPVIPLWAFASGSLALGAGAFLMQFMVQGAWGV
IPTWLNELVPANTRAVLPGFVYQLGNLLASVNATLQASIAQHHGHNYGLAMALVAGTVAIVITVLTFFGREGRVIQSAGA
GHHQPLSTSR

Specific function: May be a sugar-cation symporter involved in sialic acid uptake [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter family. Sialic acid transporter (TC 2.A.1.12.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=395, Percent_Identity=27.0886075949367, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI87082231, Length=444, Percent_Identity=24.5495495495495, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1790550, Length=436, Percent_Identity=25.2293577981651, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788292, Length=323, Percent_Identity=26.0061919504644, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081723, Length=229, Percent_Identity=27.5109170305677, Blast_Score=62, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322632, Length=413, Percent_Identity=29.7820823244552, Blast_Score=165, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004742 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44557; Mature: 44557

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure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HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA