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The map label for this gene is gntR [H]

Identifier: 238894785

GI number: 238894785

Start: 2665226

End: 2666287

Strand: Direct

Name: gntR [H]

Synonym: KP1_2795

Alternate gene names: 238894785

Gene position: 2665226-2666287 (Clockwise)

Preceding gene: 238894776

Following gene: 238894786

Centisome position: 50.78

GC content: 52.17

Gene sequence:

>1062_bases
TTGGTGATTTTGGTGAAGAGTTTAGACGCGGACGGTAGCCCGAAAGAAAAACGACGTAAAGGAACGGGTAAGATAACCCT
GACCGAGGTGGCTGAGTTTGTCGGTGTGAGCGCCATGACCGTCTCGCGAGCGCTGAGAATGCCTGAAAAAGTGAATCCTG
AGCTTCGCGATCGCATCGATGCGGCCGTCAGTCAACTCGGCTATGTCCCTAATCTGCAGGCACGTAATCTGGCCTCGGTC
CATTCCGATCTTATTCTCGCCGTCGTTCCCACCTTCTCTTCGCCGGGTTTTTTGCCGGTCTCTGAAGCGCTGCAAAAAGT
GCTGACCGAACGCGGATATACCATGATGTTTATGGAATCCGGGCATGACGGTCAAAGTGAACAAAAGACGTTTGAAAAAA
TGCTCGCCTATAACCCGGCGGCCATTATTCAGTTCAATATCGATACCATTGAGAGCTGCACCCAGTTGCTGGCCAACGTG
GATGTTCCTATTCTGGAAATTGGCGCGCTAAATACCCACCCCGTGGGTATGTGCATCGGCGTGGATTACGGTAAGGCCGT
AAAACAGATCGTGACTCATCTGGCCGACGCCTCATTAAAAAACATCGCACTGCTCTGTACCCCGGCTAATAACACAATGT
TTCGCCAGTTGCTGAGCGGATGGAATACGGCGATGCTCGCTCTGAACCGCTCCCCGCACCGGGTGGTAACCACGCATTTG
CCATCCACCATCGCCACAGGCGTCAATATATTCAAGGATATGATGATTACCTGGGGCGATCTGGATGCGTTAATTTGCAC
GTCGGATGAAATGGCCTGTGGATGTATGATGGCCTGCCACAGTGCCGGCATTAAGGTGCCCAATACCGTAGCCATTGCGA
GTTTAGGCGGAGGAGTGTTATCGACAGTCTGTTCCCCTGCCCTGACAACCGTTGAGTTTCCCTGGCATGACATTGGGGTG
AAAGCCGGTAAAGCTCTTCTCGAACTGCTTAACGATAAGCCTGGTGAAAAGTTCATTGAAATTCCGTCAGTGCTCAAAGT
CCGGGCCAGTACCGCGGCATGA

Upstream 100 bases:

>100_bases
GTTACCGCTAACACTGGCTATAATGTGCTTTCCCCCTCGCTGTGGTAAGTTATAATGCGATTCGCAGATATACTTTCGTT
ATATTTTATTTTTCAAACGG

Downstream 100 bases:

>100_bases
GTTTAATATAGGGCGATAAGGCTTCCCCTATCTAGTATCTGTGTGCGGTAGCCAGGCTTTCTACCAGGAAGAATGTCTCT
CTGCGAGAGTCCATACAATA

Product: putative periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MVILVKSLDADGSPKEKRRKGTGKITLTEVAEFVGVSAMTVSRALRMPEKVNPELRDRIDAAVSQLGYVPNLQARNLASV
HSDLILAVVPTFSSPGFLPVSEALQKVLTERGYTMMFMESGHDGQSEQKTFEKMLAYNPAAIIQFNIDTIESCTQLLANV
DVPILEIGALNTHPVGMCIGVDYGKAVKQIVTHLADASLKNIALLCTPANNTMFRQLLSGWNTAMLALNRSPHRVVTTHL
PSTIATGVNIFKDMMITWGDLDALICTSDEMACGCMMACHSAGIKVPNTVAIASLGGGVLSTVCSPALTTVEFPWHDIGV
KAGKALLELLNDKPGEKFIEIPSVLKVRASTAA

Sequences:

>Translated_353_residues
MVILVKSLDADGSPKEKRRKGTGKITLTEVAEFVGVSAMTVSRALRMPEKVNPELRDRIDAAVSQLGYVPNLQARNLASV
HSDLILAVVPTFSSPGFLPVSEALQKVLTERGYTMMFMESGHDGQSEQKTFEKMLAYNPAAIIQFNIDTIESCTQLLANV
DVPILEIGALNTHPVGMCIGVDYGKAVKQIVTHLADASLKNIALLCTPANNTMFRQLLSGWNTAMLALNRSPHRVVTTHL
PSTIATGVNIFKDMMITWGDLDALICTSDEMACGCMMACHSAGIKVPNTVAIASLGGGVLSTVCSPALTTVEFPWHDIGV
KAGKALLELLNDKPGEKFIEIPSVLKVRASTAA
>Mature_353_residues
MVILVKSLDADGSPKEKRRKGTGKITLTEVAEFVGVSAMTVSRALRMPEKVNPELRDRIDAAVSQLGYVPNLQARNLASV
HSDLILAVVPTFSSPGFLPVSEALQKVLTERGYTMMFMESGHDGQSEQKTFEKMLAYNPAAIIQFNIDTIESCTQLLANV
DVPILEIGALNTHPVGMCIGVDYGKAVKQIVTHLADASLKNIALLCTPANNTMFRQLLSGWNTAMLALNRSPHRVVTTHL
PSTIATGVNIFKDMMITWGDLDALICTSDEMACGCMMACHSAGIKVPNTVAIASLGGGVLSTVCSPALTTVEFPWHDIGV
KAGKALLELLNDKPGEKFIEIPSVLKVRASTAA

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=302, Percent_Identity=29.1390728476821, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790715, Length=304, Percent_Identity=26.9736842105263, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790369, Length=364, Percent_Identity=27.4725274725275, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789068, Length=300, Percent_Identity=27, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789202, Length=302, Percent_Identity=25.4966887417219, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787580, Length=331, Percent_Identity=22.6586102719033, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1786540, Length=340, Percent_Identity=23.8235294117647, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790194, Length=303, Percent_Identity=21.7821782178218, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788474, Length=296, Percent_Identity=24.6621621621622, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790689, Length=327, Percent_Identity=23.8532110091743, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37876; Mature: 37876

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVILVKSLDADGSPKEKRRKGTGKITLTEVAEFVGVSAMTVSRALRMPEKVNPELRDRID
CEEEEEECCCCCCCHHHHHCCCCCEEHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHH
AAVSQLGYVPNLQARNLASVHSDLILAVVPTFSSPGFLPVSEALQKVLTERGYTMMFMES
HHHHHHCCCCCCCCCHHHHHHHCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEC
GHDGQSEQKTFEKMLAYNPAAIIQFNIDTIESCTQLLANVDVPILEIGALNTHPVGMCIG
CCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEE
VDYGKAVKQIVTHLADASLKNIALLCTPANNTMFRQLLSGWNTAMLALNRSPHRVVTTHL
CCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCEEEEECC
PSTIATGVNIFKDMMITWGDLDALICTSDEMACGCMMACHSAGIKVPNTVAIASLGGGVL
CHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHH
STVCSPALTTVEFPWHDIGVKAGKALLELLNDKPGEKFIEIPSVLKVRASTAA
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHCCC
>Mature Secondary Structure
MVILVKSLDADGSPKEKRRKGTGKITLTEVAEFVGVSAMTVSRALRMPEKVNPELRDRID
CEEEEEECCCCCCCHHHHHCCCCCEEHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHH
AAVSQLGYVPNLQARNLASVHSDLILAVVPTFSSPGFLPVSEALQKVLTERGYTMMFMES
HHHHHHCCCCCCCCCHHHHHHHCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEC
GHDGQSEQKTFEKMLAYNPAAIIQFNIDTIESCTQLLANVDVPILEIGALNTHPVGMCIG
CCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEE
VDYGKAVKQIVTHLADASLKNIALLCTPANNTMFRQLLSGWNTAMLALNRSPHRVVTTHL
CCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCEEEEECC
PSTIATGVNIFKDMMITWGDLDALICTSDEMACGCMMACHSAGIKVPNTVAIASLGGGVL
CHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHH
STVCSPALTTVEFPWHDIGVKAGKALLELLNDKPGEKFIEIPSVLKVRASTAA
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]