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The map label for this gene is dapE [H]

Identifier: 238894771

GI number: 238894771

Start: 2653466

End: 2654608

Strand: Direct

Name: dapE [H]

Synonym: KP1_2779

Alternate gene names: 238894771

Gene position: 2653466-2654608 (Clockwise)

Preceding gene: 238894770

Following gene: 238894772

Centisome position: 50.56

GC content: 61.77

Gene sequence:

>1143_bases
ATGACCGCGACCCTTGAGCTCGCCCGGCAGCTGCTGGGCTTTAACACCATCAACCCGCCGGGCAGCGAAGCCGACTGCAT
GCGGTTCTTCGCCGACTGGCTTGACGATAGCGGTTTTGAGGTTTCGCTGTCGTCGTTCGGCGAAGGACGCTGCAATCTTA
TCGCCAGCCTGCCCGGGGCGAAGAGCGGTAAACCGCTGGCCTTTACCGGACATCTGGATACCGTCCCGCTGGGAAATGCC
CGCTGGCAGTACGATCCTTTCGGCTCGCAGATGGAAGACGGGCGTCTTTATGGCCGCGGATCCAGCGATATGAAAGCGGC
GATAGCGGCGTTTGCCGTCGCCTGCGTTCATCAGCGGGAAGCGATCCTCGCCGGACGCGGCGCGGTATTGCTGATAACCG
GCGGAGAAGAGACCGGCTGCGACGGCGCGCGGGCGCTGATCGCCTCCGCAACGTTGCCGGAGGTGGGCGCGCTGATCGTC
GGTGAACCCACCGCCAACTATCCGGTTATCGGCCATAAAGGCGCGCTCTGGCTACGCTGCGAAACGCGGGGGAAAACCGC
CCACGGCGCGATGCCGGAGCTGGGGATCAATGCTATTTATCTTGCGGCGGATGCGTTGGGTAAGATTCAGCATTTTTCGC
CAGGCGCGCCGCATCCGCTAATGAAGCAACCCACCCTCAACGTCGGACGCATAGAAGGCGGACTCAATATTAATTCCGTA
CCGGACCGCACGCGTTTTGATGTCGATATCCGCAGCGCGCCCAATTTACAGCACGCCACTATCCGGGAGCGCTTGACGAC
GCTGCTTGGCGAAAGCGTCACCGTCTCCACGCTGGTCGACCTGCCCGCCGTCCTCAGCCGGGAGGATCATGCGTGGATTA
AGCAGGTTTATCAACGCTGTCAGCCGCTGCACGCTGAGCCGATTGCGCCGCGCGTGGTGCCCTACTTTACCGACGCCTCG
CTGCTGCTGCCTGCATTGGGCGATCCGCCCTGTATTATTCTCGGCCCCGGCGAGCCGTCGATGGCGCATCAAACCGACGA
ATACTGCCTGCTCAGCCGACTGGCGGAGGCCGAACAGCTATACGGTGACATCATTCGCGACTGGATGGCATCACCGCCCG
CGACGAAAGTAAAAAATGAGTGA

Upstream 100 bases:

>100_bases
GCGACATGTCGGCGCACTGGCTGCCGGAAGAGTTTGCCAAATGGCCCGGCTATCGCCAGCTGTGGATTAACTGCCTCGAC
TGGCTGACGGAACGCCGCTG

Downstream 100 bases:

>100_bases
CACTGTCACTGAAAGCGCGTGCCATGCAATTCAGCGTTTGAATAATATCGCGGAATAACAGAGGATAACCGCCTCGTACA
CGACGGTATCACCACCAGCA

Product: putative acetylornithine deacetylase

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTATLELARQLLGFNTINPPGSEADCMRFFADWLDDSGFEVSLSSFGEGRCNLIASLPGAKSGKPLAFTGHLDTVPLGNA
RWQYDPFGSQMEDGRLYGRGSSDMKAAIAAFAVACVHQREAILAGRGAVLLITGGEETGCDGARALIASATLPEVGALIV
GEPTANYPVIGHKGALWLRCETRGKTAHGAMPELGINAIYLAADALGKIQHFSPGAPHPLMKQPTLNVGRIEGGLNINSV
PDRTRFDVDIRSAPNLQHATIRERLTTLLGESVTVSTLVDLPAVLSREDHAWIKQVYQRCQPLHAEPIAPRVVPYFTDAS
LLLPALGDPPCIILGPGEPSMAHQTDEYCLLSRLAEAEQLYGDIIRDWMASPPATKVKNE

Sequences:

>Translated_380_residues
MTATLELARQLLGFNTINPPGSEADCMRFFADWLDDSGFEVSLSSFGEGRCNLIASLPGAKSGKPLAFTGHLDTVPLGNA
RWQYDPFGSQMEDGRLYGRGSSDMKAAIAAFAVACVHQREAILAGRGAVLLITGGEETGCDGARALIASATLPEVGALIV
GEPTANYPVIGHKGALWLRCETRGKTAHGAMPELGINAIYLAADALGKIQHFSPGAPHPLMKQPTLNVGRIEGGLNINSV
PDRTRFDVDIRSAPNLQHATIRERLTTLLGESVTVSTLVDLPAVLSREDHAWIKQVYQRCQPLHAEPIAPRVVPYFTDAS
LLLPALGDPPCIILGPGEPSMAHQTDEYCLLSRLAEAEQLYGDIIRDWMASPPATKVKNE
>Mature_379_residues
TATLELARQLLGFNTINPPGSEADCMRFFADWLDDSGFEVSLSSFGEGRCNLIASLPGAKSGKPLAFTGHLDTVPLGNAR
WQYDPFGSQMEDGRLYGRGSSDMKAAIAAFAVACVHQREAILAGRGAVLLITGGEETGCDGARALIASATLPEVGALIVG
EPTANYPVIGHKGALWLRCETRGKTAHGAMPELGINAIYLAADALGKIQHFSPGAPHPLMKQPTLNVGRIEGGLNINSVP
DRTRFDVDIRSAPNLQHATIRERLTTLLGESVTVSTLVDLPAVLSREDHAWIKQVYQRCQPLHAEPIAPRVVPYFTDASL
LLPALGDPPCIILGPGEPSMAHQTDEYCLLSRLAEAEQLYGDIIRDWMASPPATKVKNE

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=388, Percent_Identity=22.9381443298969, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1790395, Length=368, Percent_Identity=30.4347826086957, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788816, Length=281, Percent_Identity=27.7580071174377, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789236, Length=331, Percent_Identity=25.6797583081571, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538640, Length=405, Percent_Identity=23.2098765432099, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538642, Length=406, Percent_Identity=23.6453201970443, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982710, Length=302, Percent_Identity=24.8344370860927, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17551016, Length=307, Percent_Identity=27.6872964169381, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 40751; Mature: 40620

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATLELARQLLGFNTINPPGSEADCMRFFADWLDDSGFEVSLSSFGEGRCNLIASLPGA
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCC
KSGKPLAFTGHLDTVPLGNARWQYDPFGSQMEDGRLYGRGSSDMKAAIAAFAVACVHQRE
CCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
AILAGRGAVLLITGGEETGCDGARALIASATLPEVGALIVGEPTANYPVIGHKGALWLRC
HHEECCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCEEECCCEEEEEE
ETRGKTAHGAMPELGINAIYLAADALGKIQHFSPGAPHPLMKQPTLNVGRIEGGLNINSV
ECCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
PDRTRFDVDIRSAPNLQHATIRERLTTLLGESVTVSTLVDLPAVLSREDHAWIKQVYQRC
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHC
QPLHAEPIAPRVVPYFTDASLLLPALGDPPCIILGPGEPSMAHQTDEYCLLSRLAEAEQL
CCCCCCCCCCCEEEEECCHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
YGDIIRDWMASPPATKVKNE
HHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TATLELARQLLGFNTINPPGSEADCMRFFADWLDDSGFEVSLSSFGEGRCNLIASLPGA
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCC
KSGKPLAFTGHLDTVPLGNARWQYDPFGSQMEDGRLYGRGSSDMKAAIAAFAVACVHQRE
CCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
AILAGRGAVLLITGGEETGCDGARALIASATLPEVGALIVGEPTANYPVIGHKGALWLRC
HHEECCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCEEECCCEEEEEE
ETRGKTAHGAMPELGINAIYLAADALGKIQHFSPGAPHPLMKQPTLNVGRIEGGLNINSV
ECCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
PDRTRFDVDIRSAPNLQHATIRERLTTLLGESVTVSTLVDLPAVLSREDHAWIKQVYQRC
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHC
QPLHAEPIAPRVVPYFTDASLLLPALGDPPCIILGPGEPSMAHQTDEYCLLSRLAEAEQL
CCCCCCCCCCCEEEEECCHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
YGDIIRDWMASPPATKVKNE
HHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA