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The map label for this gene is opd [H]

Identifier: 238894769

GI number: 238894769

Start: 2651617

End: 2652696

Strand: Direct

Name: opd [H]

Synonym: KP1_2777

Alternate gene names: 238894769

Gene position: 2651617-2652696 (Clockwise)

Preceding gene: 238894768

Following gene: 238894770

Centisome position: 50.52

GC content: 58.8

Gene sequence:

>1080_bases
ATGAAAGGATCAATTTTTCGCCATCCCTCCCCGCTGCCGGTTGGCGTTAGCAGCGGTTATGTAATGACTGTGCTTGGCCC
ACTGCCGATTAACGAAATGGGCGTTACTCTGATGCATGAGCATATTCTGCTGGATGCCTCCGGCAAATGGGTGCCGCCCT
GCTGCTGCAGCGATCGCCATCTTGCCGAAATGCCGGTGAAAATGGAAAACCTTGGCGAACTGTCGCTCAACCCGCTGATG
AGCCGCGATAACTGTCAGCTGTTTGATGTCGACGTTGCGATTGACGAGCTGACTAAATATCGCGCCCTTGGCGGAGAAAC
GGTAGTCGACCCGACCAATATCGGCATTGGCCGCGATCCGAAAGCGCTGGCGCGCATCGCGCGGCTGACCGGTCTGAACA
TCATTATGGGTACCGGGCTCTATCTGGAACCTTCGCACCCTGAGTGGGTAAAAATCAGCAGCGTCGAACAGCTGACCGAA
CGGCTGATTTACGATCTTGGCGGCGCGGAGGAGAAACCGGAGGTGCTCGCCGGGCTCATCGGCGAAATCGGTATCTCCAG
CCGCTTTACGCCGGATGAGGAGAAATCCCTGCGCGCTGCGGGTCGGGCCAGCGCCGCGACCGGCGTGCCGATCGAGGTCC
ATCTGCCCGGCTGGGAGCGGCTGGGCCATCGGGTGCTGGATATTCTCGAGCAGGAAGGCGCCGATTTACGCCATACCGTG
CTGTGCCATATGAATCCCAGCTTTGCCGATAAGCGCTACCAGCGCGAACTGGCGCAGCGCGGGGCGTTTCTCGAATACGA
CATGATTGGCATGAGCTATTACTACGCCGACGAGTCGGCGCAGTCGCCCTCCGACGAGGAGAACGCCCGCGCGATCCGCG
AGCTGATTGACGACGGCTACATCCAGCAAATTCTGCTGTCGCAGGACGTCTTCCTGAAAACCATGCTCACCCGCTACGGC
GGCCACGGTTATGGCTACATACTCAAGCATTTTGTTCCCCGTCTGCGGCGCCACGGCGTCAGCGGCGAACAACTTGAAAC
CTTAATGATTGGAAACCCCCAGCGGGTCTTTGGCGGATAA

Upstream 100 bases:

>100_bases
GTTTTACACCCAGATAGCCACCGGCACCATTATCCTGCTGGCTATCTGGCTGAACACCCGCATTCTCAACCCGACGCGCT
CCGCGGCAAAAGGATAGCTG

Downstream 100 bases:

>100_bases
AAGGAAACGTCATCATGCAGAAAAAAATCTTACTGGTCGGTGAGTCCTGGACCAGCACGTCAACGCACGTTAAAGGCTTC
GACCAGTTTGCCACCGCCAC

Product: putative hydrolase

Products: NA

Alternate protein names: Phosphotriesterase; PTE [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKGSIFRHPSPLPVGVSSGYVMTVLGPLPINEMGVTLMHEHILLDASGKWVPPCCCSDRHLAEMPVKMENLGELSLNPLM
SRDNCQLFDVDVAIDELTKYRALGGETVVDPTNIGIGRDPKALARIARLTGLNIIMGTGLYLEPSHPEWVKISSVEQLTE
RLIYDLGGAEEKPEVLAGLIGEIGISSRFTPDEEKSLRAAGRASAATGVPIEVHLPGWERLGHRVLDILEQEGADLRHTV
LCHMNPSFADKRYQRELAQRGAFLEYDMIGMSYYYADESAQSPSDEENARAIRELIDDGYIQQILLSQDVFLKTMLTRYG
GHGYGYILKHFVPRLRRHGVSGEQLETLMIGNPQRVFGG

Sequences:

>Translated_359_residues
MKGSIFRHPSPLPVGVSSGYVMTVLGPLPINEMGVTLMHEHILLDASGKWVPPCCCSDRHLAEMPVKMENLGELSLNPLM
SRDNCQLFDVDVAIDELTKYRALGGETVVDPTNIGIGRDPKALARIARLTGLNIIMGTGLYLEPSHPEWVKISSVEQLTE
RLIYDLGGAEEKPEVLAGLIGEIGISSRFTPDEEKSLRAAGRASAATGVPIEVHLPGWERLGHRVLDILEQEGADLRHTV
LCHMNPSFADKRYQRELAQRGAFLEYDMIGMSYYYADESAQSPSDEENARAIRELIDDGYIQQILLSQDVFLKTMLTRYG
GHGYGYILKHFVPRLRRHGVSGEQLETLMIGNPQRVFGG
>Mature_359_residues
MKGSIFRHPSPLPVGVSSGYVMTVLGPLPINEMGVTLMHEHILLDASGKWVPPCCCSDRHLAEMPVKMENLGELSLNPLM
SRDNCQLFDVDVAIDELTKYRALGGETVVDPTNIGIGRDPKALARIARLTGLNIIMGTGLYLEPSHPEWVKISSVEQLTE
RLIYDLGGAEEKPEVLAGLIGEIGISSRFTPDEEKSLRAAGRASAATGVPIEVHLPGWERLGHRVLDILEQEGADLRHTV
LCHMNPSFADKRYQRELAQRGAFLEYDMIGMSYYYADESAQSPSDEENARAIRELIDDGYIQQILLSQDVFLKTMLTRYG
GHGYGYILKHFVPRLRRHGVSGEQLETLMIGNPQRVFGG

Specific function: Has an unusual substrate specificity for synthetic organophosphate triesters and phosphorofluoridates. All of the phosphate triesters found to be substrates are synthetic compounds. The identity of any naturally occurring substrate for the enzyme is unkno

COG id: COG1735

COG function: function code R; Predicted metal-dependent hydrolase with the TIM-barrel fold

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphotriesterase family [H]

Homologues:

Organism=Homo sapiens, GI20070186, Length=341, Percent_Identity=35.1906158357771, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI47933341, Length=341, Percent_Identity=35.1906158357771, Blast_Score=203, Evalue=2e-52,
Organism=Escherichia coli, GI1789780, Length=333, Percent_Identity=28.8288288288288, Blast_Score=134, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24645325, Length=342, Percent_Identity=28.0701754385965, Blast_Score=152, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017947
- InterPro:   IPR001559
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02126 PTE [H]

EC number: =3.1.8.1 [H]

Molecular weight: Translated: 39793; Mature: 39793

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01322 PHOSPHOTRIESTERASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSIFRHPSPLPVGVSSGYVMTVLGPLPINEMGVTLMHEHILLDASGKWVPPCCCSDRH
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHEEEEEEEEECCCCCCCCCCCCCCC
LAEMPVKMENLGELSLNPLMSRDNCQLFDVDVAIDELTKYRALGGETVVDPTNIGIGRDP
HHHCCCCHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEECCCCCCCCCCH
KALARIARLTGLNIIMGTGLYLEPSHPEWVKISSVEQLTERLIYDLGGAEEKPEVLAGLI
HHHHHHHHHHCCEEEEECCEEECCCCCCEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GEIGISSRFTPDEEKSLRAAGRASAATGVPIEVHLPGWERLGHRVLDILEQEGADLRHTV
HHHCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEE
LCHMNPSFADKRYQRELAQRGAFLEYDMIGMSYYYADESAQSPSDEENARAIRELIDDGY
EEECCCHHHHHHHHHHHHHCCCEEEEEEECEEEEECCCCCCCCCCHHHHHHHHHHHCCHH
IQQILLSQDVFLKTMLTRYGGHGYGYILKHFVPRLRRHGVSGEQLETLMIGNPQRVFGG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEECCCHHHCCC
>Mature Secondary Structure
MKGSIFRHPSPLPVGVSSGYVMTVLGPLPINEMGVTLMHEHILLDASGKWVPPCCCSDRH
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHEEEEEEEEECCCCCCCCCCCCCCC
LAEMPVKMENLGELSLNPLMSRDNCQLFDVDVAIDELTKYRALGGETVVDPTNIGIGRDP
HHHCCCCHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEECCCCCCCCCCH
KALARIARLTGLNIIMGTGLYLEPSHPEWVKISSVEQLTERLIYDLGGAEEKPEVLAGLI
HHHHHHHHHHCCEEEEECCEEECCCCCCEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GEIGISSRFTPDEEKSLRAAGRASAATGVPIEVHLPGWERLGHRVLDILEQEGADLRHTV
HHHCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEE
LCHMNPSFADKRYQRELAQRGAFLEYDMIGMSYYYADESAQSPSDEENARAIRELIDDGY
EEECCCHHHHHHHHHHHHHCCCEEEEEEECEEEEECCCCCCCCCCHHHHHHHHHHHCCHH
IQQILLSQDVFLKTMLTRYGGHGYGYILKHFVPRLRRHGVSGEQLETLMIGNPQRVFGG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2834339; 8155644; 7999757; 7794910; 8634243 [H]