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The map label for this gene is xylB [H]

Identifier: 238894749

GI number: 238894749

Start: 2631329

End: 2632867

Strand: Direct

Name: xylB [H]

Synonym: KP1_2756

Alternate gene names: 238894749

Gene position: 2631329-2632867 (Clockwise)

Preceding gene: 238894748

Following gene: 238894750

Centisome position: 50.13

GC content: 58.87

Gene sequence:

>1539_bases
GTGGCCCGCCTTAAGACGTCACCGGAGTTAGTGATGAAAGATAAAATACTCACGATTGATGTTGGCACTGGCAGTACCCG
CGCCGCTATTGTGCGCATTGACGGCGCGATGATCGGCTTTGCGCAAAGAGAGTATGAGCAAACCACGCCGCGTGCAGGTT
GGTCAGAACAGGCCCCGTCTTTATGGTGGCAGGCCGCCTGCGACTGTATACGCGAGGTGCTTTACCGCTATCCTGAAACG
GCAGCGCAAATTGCGGTTATTGGTGCTTGCGGACAGATGCATGGCACCGTCCTTCTGGACGACCGTGGCGAGCTGGTGGA
GGATAGGGCGTTGCTGTGGAATGATAAGCGCAGCCAGCCGCAAGTTGACGCCTTTAACGCGCGCGAAGGTTGGGAAAAGT
GGCTGGCGCATTTGAATAATCCGCCTGCGGCAGCATGGCCCGCTTTCAAGTTAGCCTGGTGGCGCGAAAATCATCCGGAT
CGCTGGTCGCAGCTCGCCAAAGTATTAATGCCGAAGGACTATATTAATTTCATGCTGACCGGTGCCATGGCGACCGATTA
TAGCGAAGCGTCGTGCTATTTCCTGATGGACAGCGAAACCCGTAGCTGGTCTTCGCAAGCCTGCGAAACGTTTGGTCTGC
GGGTCGATCAGCTCCCGGAGCTTAAACTTTCCAGCGACATAATCGGCCAGGTGACGCAGCGCGCAGCCGACCTGACGGGC
CTGCCGGCGGGTATCCCGGTGGTTGCCGGGACGTCGGATATGGCGGCCTCTCTGCTGGGCTCGGGTGTGTATGAACCGGG
GATGGCGTCTGATTCAACCGGCACGTCGACGCTGATGACGGTGGTGTCGCCGCGGCCGTTACACCATCCGCTGGTTAATA
ATCTTCATCTTGCCAACGCGGCCTGGGGCGGATTTACGATCCTCGACGCCGGCGGCGATGCCGTTCGCTGGGCGCGGCTG
GCACTTGCCGATAACCAGATTACGCATCCACAGCTTTTACAGGAAGCGGCGGCGGTGCCGGCGGGGGCAGAAGGGCTGCT
GTTTCTTCCCTATCTGACGGGAGAACGTCTGGCCGAACACACGAACTCGCGGGCACAGTTTTTTGGCCTGCAGCGCAAGC
ATCGCCGCGGTCATTTATTCCGCGCAGTTCTGGAAGGGGTGGCCTTTGCATCCTGGCGCAATCTTCGGCAGCTGCAGAAG
TGCGGGCAGTATCCGCAACAAATGATCGCTTCCGGCGGCGGCGCGCGCAGCTCGCTGTGGCTTGAAATCAAAGCCGCAGC
GTACAATCTGCCGATATTATCTACGCGTAATCAGGAGAATGGCGTCACCGGATGCGGTATTATCGCCGGGGTTGGCGTAG
GGTTGTACGCCGATTTTGCCAGCGGCGTGCGGCAAACGGTGCAGTTCGACAAACTGATCTCACCGGATCCCCGTCTGCGG
GATTATTACCACGCCTGCTGCGAGCTTTTTGATACGCTGTACCGGCAATCCGCCGCCTTATACGACAGGCTGGATGCGCT
CAGCGTAGGACCCGACTGA

Upstream 100 bases:

>100_bases
TGAGCCATGGCGCGGTAACCAAGGTGCTGGCTGAACTGGAGCAGCACCCGGAACGTTTTCCCGAGCTGAACGCCGATTAA
ACTGAGAGACCGCGGGCCTG

Downstream 100 bases:

>100_bases
TACGCAAAGGTAAGCCAGCGCCGCTGCGCGCGTAACGAGCTGTAAAAAAGAGAGAGGCAGAATGTTTGCAGAAGAAAGAC
AGGAGAAGTTACTCGGTATT

Product: putative pentose kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MARLKTSPELVMKDKILTIDVGTGSTRAAIVRIDGAMIGFAQREYEQTTPRAGWSEQAPSLWWQAACDCIREVLYRYPET
AAQIAVIGACGQMHGTVLLDDRGELVEDRALLWNDKRSQPQVDAFNAREGWEKWLAHLNNPPAAAWPAFKLAWWRENHPD
RWSQLAKVLMPKDYINFMLTGAMATDYSEASCYFLMDSETRSWSSQACETFGLRVDQLPELKLSSDIIGQVTQRAADLTG
LPAGIPVVAGTSDMAASLLGSGVYEPGMASDSTGTSTLMTVVSPRPLHHPLVNNLHLANAAWGGFTILDAGGDAVRWARL
ALADNQITHPQLLQEAAAVPAGAEGLLFLPYLTGERLAEHTNSRAQFFGLQRKHRRGHLFRAVLEGVAFASWRNLRQLQK
CGQYPQQMIASGGGARSSLWLEIKAAAYNLPILSTRNQENGVTGCGIIAGVGVGLYADFASGVRQTVQFDKLISPDPRLR
DYYHACCELFDTLYRQSAALYDRLDALSVGPD

Sequences:

>Translated_512_residues
MARLKTSPELVMKDKILTIDVGTGSTRAAIVRIDGAMIGFAQREYEQTTPRAGWSEQAPSLWWQAACDCIREVLYRYPET
AAQIAVIGACGQMHGTVLLDDRGELVEDRALLWNDKRSQPQVDAFNAREGWEKWLAHLNNPPAAAWPAFKLAWWRENHPD
RWSQLAKVLMPKDYINFMLTGAMATDYSEASCYFLMDSETRSWSSQACETFGLRVDQLPELKLSSDIIGQVTQRAADLTG
LPAGIPVVAGTSDMAASLLGSGVYEPGMASDSTGTSTLMTVVSPRPLHHPLVNNLHLANAAWGGFTILDAGGDAVRWARL
ALADNQITHPQLLQEAAAVPAGAEGLLFLPYLTGERLAEHTNSRAQFFGLQRKHRRGHLFRAVLEGVAFASWRNLRQLQK
CGQYPQQMIASGGGARSSLWLEIKAAAYNLPILSTRNQENGVTGCGIIAGVGVGLYADFASGVRQTVQFDKLISPDPRLR
DYYHACCELFDTLYRQSAALYDRLDALSVGPD
>Mature_511_residues
ARLKTSPELVMKDKILTIDVGTGSTRAAIVRIDGAMIGFAQREYEQTTPRAGWSEQAPSLWWQAACDCIREVLYRYPETA
AQIAVIGACGQMHGTVLLDDRGELVEDRALLWNDKRSQPQVDAFNAREGWEKWLAHLNNPPAAAWPAFKLAWWRENHPDR
WSQLAKVLMPKDYINFMLTGAMATDYSEASCYFLMDSETRSWSSQACETFGLRVDQLPELKLSSDIIGQVTQRAADLTGL
PAGIPVVAGTSDMAASLLGSGVYEPGMASDSTGTSTLMTVVSPRPLHHPLVNNLHLANAAWGGFTILDAGGDAVRWARLA
LADNQITHPQLLQEAAAVPAGAEGLLFLPYLTGERLAEHTNSRAQFFGLQRKHRRGHLFRAVLEGVAFASWRNLRQLQKC
GQYPQQMIASGGGARSSLWLEIKAAAYNLPILSTRNQENGVTGCGIIAGVGVGLYADFASGVRQTVQFDKLISPDPRLRD
YYHACCELFDTLYRQSAALYDRLDALSVGPD

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=473, Percent_Identity=23.2558139534884, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI189409120, Length=473, Percent_Identity=23.2558139534884, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI4504007, Length=473, Percent_Identity=23.2558139534884, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI41393575, Length=440, Percent_Identity=23.6363636363636, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI88196792, Length=521, Percent_Identity=20.9213051823417, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1787789, Length=532, Percent_Identity=29.6992481203008, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789987, Length=492, Percent_Identity=29.6747967479675, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1790005, Length=502, Percent_Identity=25.4980079681275, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1789168, Length=469, Percent_Identity=25.7995735607676, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1790361, Length=469, Percent_Identity=23.454157782516, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789138, Length=488, Percent_Identity=24.3852459016393, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17535599, Length=449, Percent_Identity=25.3897550111359, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24655555, Length=462, Percent_Identity=25.5411255411255, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24655560, Length=462, Percent_Identity=25.5411255411255, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24655570, Length=462, Percent_Identity=25.5411255411255, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24655574, Length=462, Percent_Identity=25.5411255411255, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24655565, Length=462, Percent_Identity=25.5411255411255, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17864214, Length=461, Percent_Identity=25.3796095444685, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24657106, Length=525, Percent_Identity=22.2857142857143, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24657102, Length=525, Percent_Identity=22.2857142857143, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24654573, Length=393, Percent_Identity=24.6819338422392, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 56254; Mature: 56123

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLKTSPELVMKDKILTIDVGTGSTRAAIVRIDGAMIGFAQREYEQTTPRAGWSEQAPS
CCCCCCCCCCEEECEEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHH
LWWQAACDCIREVLYRYPETAAQIAVIGACGQMHGTVLLDDRGELVEDRALLWNDKRSQP
HHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCEEEECCCCCHHHHHHHHCCCCCCCC
QVDAFNAREGWEKWLAHLNNPPAAAWPAFKLAWWRENHPDRWSQLAKVLMPKDYINFMLT
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHH
GAMATDYSEASCYFLMDSETRSWSSQACETFGLRVDQLPELKLSSDIIGQVTQRAADLTG
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
LPAGIPVVAGTSDMAASLLGSGVYEPGMASDSTGTSTLMTVVSPRPLHHPLVNNLHLANA
CCCCCCEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHCCEEEECC
AWGGFTILDAGGDAVRWARLALADNQITHPQLLQEAAAVPAGAEGLLFLPYLTGERLAEH
CCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHH
TNSRAQFFGLQRKHRRGHLFRAVLEGVAFASWRNLRQLQKCGQYPQQMIASGGGARSSLW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LEIKAAAYNLPILSTRNQENGVTGCGIIAGVGVGLYADFASGVRQTVQFDKLISPDPRLR
EEEEEEEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
DYYHACCELFDTLYRQSAALYDRLDALSVGPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARLKTSPELVMKDKILTIDVGTGSTRAAIVRIDGAMIGFAQREYEQTTPRAGWSEQAPS
CCCCCCCCCEEECEEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHH
LWWQAACDCIREVLYRYPETAAQIAVIGACGQMHGTVLLDDRGELVEDRALLWNDKRSQP
HHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCEEEECCCCCHHHHHHHHCCCCCCCC
QVDAFNAREGWEKWLAHLNNPPAAAWPAFKLAWWRENHPDRWSQLAKVLMPKDYINFMLT
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHH
GAMATDYSEASCYFLMDSETRSWSSQACETFGLRVDQLPELKLSSDIIGQVTQRAADLTG
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
LPAGIPVVAGTSDMAASLLGSGVYEPGMASDSTGTSTLMTVVSPRPLHHPLVNNLHLANA
CCCCCCEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHCCEEEECC
AWGGFTILDAGGDAVRWARLALADNQITHPQLLQEAAAVPAGAEGLLFLPYLTGERLAEH
CCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHH
TNSRAQFFGLQRKHRRGHLFRAVLEGVAFASWRNLRQLQKCGQYPQQMIASGGGARSSLW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LEIKAAAYNLPILSTRNQENGVTGCGIIAGVGVGLYADFASGVRQTVQFDKLISPDPRLR
EEEEEEEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
DYYHACCELFDTLYRQSAALYDRLDALSVGPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]