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The map label for this gene is ttuB [H]

Identifier: 238894737

GI number: 238894737

Start: 2619067

End: 2620404

Strand: Reverse

Name: ttuB [H]

Synonym: KP1_2744

Alternate gene names: 238894737

Gene position: 2620404-2619067 (Counterclockwise)

Preceding gene: 238894738

Following gene: 238894736

Centisome position: 49.93

GC content: 58.67

Gene sequence:

>1338_bases
ATGTCCGCAATAAATGAAAAGGCGGTAAACGGGACGCAGCTGCAACGCACCCATAAAAAAATCTACCGCCATTTGATGCC
GCTGCTTATCGTGGCGTACATCATCAGCTTTATTGATCGTACCAATATTGGCATGGCGAAAGCGACCATGTCGGTGGATA
TCGGCCTTTCCGCAACCGCATTCGGCCTCGGGGCCGGGTTGTTTTTTCTCACCTACGCAGTGCTGGAGATCCCCAGTAAC
CTGTTTCTCACCCGGATTGGCGCACGGCGCTGGATAGCTCGCATCATGATTACCTGGGGCATCCTCTCCTGCGGTATGGC
GTTTGTCACCGGGCCTACGTCCTTTTACGTGATGCGCCTTCTGCTCGGCGCCGCCGAAGCGGGACTCTATCCGGGCATTA
TTTACTACCTCACCCTCTGGTTTGGCCGCGAAGAGCGCGCAAAAGCCACCGGCCTGTTCCTGCTGGGGGTCTGTCTGGCC
AATATTATCGGCGCGCCGCTGGGCGGATTGTTATTAAGCCTTGATGGCATGTCCGGCTGGCACGGCTGGCAGTGGATGTT
CTTTATCGAAGGGCTGCCTGCGATAGCGCTGGCGTTCGTCGTCTGGCGCAGACTGCCGGATAAACCAGCCGACGCCCGCT
GGCTGGACAGCGACGATGTGCAAGCCATTAACGCGGTACTGGCGAAAGAAGCCGAGGAAACACGCCATACGCCGAGCCGT
TTCTCCCTGAAAACCGCGCTGTCCACCCGAGTGTTTTTGTTGCTGGTGCTGATTTACTTTACCCACCAGTTTTCGGTTTA
CGGCCTGAGTTATTTCCTGCCGGGGATCATCGGTAGCTGGGGCCAGCTTACTCCGCTGCAGATTGGTCTGCTGACCGCCA
TCCCGTGGATTGCCGCCGCCGCGGGTGGGATCCTGCTGCCGCGATTCGCCCGCACGGAACAGCGTTCCCGCAGCATGCTG
ATGGCCGGATATCTGGTCATGGCGACCGGTATGGCGATTGGCGCCATTGCCGGCCACGGTGTGGCGCTGCTTGGCTTCTC
GCTGGCCGCTTTCATGTTCTTCGCTATGCAATCCATCATCTTTAACTGGCTCCCGTCCATCATGAGCGGGCATATGCTGG
CGGGCAGCTTCGGCCTGCTCAACTGCCTCGGGCTGTGCGGGGGCTTTCTCGGGCCGTTTATTCTCGGCGCGTTTGAGGAC
CGCACCGGTGCGGCAACGTCCGGCTTATGGTTCGCTGTCGCGCTACTGATTATCGGCGCGCTGGTGTCCCTGTTTCTCAA
AAGTTCCTCATCCCCAGGTTCCGTATCGGCGAAACAGGCCCACGGCGAAAAAGTGTAA

Upstream 100 bases:

>100_bases
GTCGTTCGGGTCAGCACCCGGCGACAACCTGTGAGCTGACGAACGGGATCGTCTCGATCCCGGCAAGGCTTCTGACCACG
AATACGGGGAAATAATAACC

Downstream 100 bases:

>100_bases
TCAGGAGGCCATTATGCGCATTGAAGTGTTACTGGATTTAAAAACCCGACTCGGCGAAAGCCCGGTCTGGGATGTCGAAC
AGCAGCGTCTTTGGTGGGTG

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSAINEKAVNGTQLQRTHKKIYRHLMPLLIVAYIISFIDRTNIGMAKATMSVDIGLSATAFGLGAGLFFLTYAVLEIPSN
LFLTRIGARRWIARIMITWGILSCGMAFVTGPTSFYVMRLLLGAAEAGLYPGIIYYLTLWFGREERAKATGLFLLGVCLA
NIIGAPLGGLLLSLDGMSGWHGWQWMFFIEGLPAIALAFVVWRRLPDKPADARWLDSDDVQAINAVLAKEAEETRHTPSR
FSLKTALSTRVFLLLVLIYFTHQFSVYGLSYFLPGIIGSWGQLTPLQIGLLTAIPWIAAAAGGILLPRFARTEQRSRSML
MAGYLVMATGMAIGAIAGHGVALLGFSLAAFMFFAMQSIIFNWLPSIMSGHMLAGSFGLLNCLGLCGGFLGPFILGAFED
RTGAATSGLWFAVALLIIGALVSLFLKSSSSPGSVSAKQAHGEKV

Sequences:

>Translated_445_residues
MSAINEKAVNGTQLQRTHKKIYRHLMPLLIVAYIISFIDRTNIGMAKATMSVDIGLSATAFGLGAGLFFLTYAVLEIPSN
LFLTRIGARRWIARIMITWGILSCGMAFVTGPTSFYVMRLLLGAAEAGLYPGIIYYLTLWFGREERAKATGLFLLGVCLA
NIIGAPLGGLLLSLDGMSGWHGWQWMFFIEGLPAIALAFVVWRRLPDKPADARWLDSDDVQAINAVLAKEAEETRHTPSR
FSLKTALSTRVFLLLVLIYFTHQFSVYGLSYFLPGIIGSWGQLTPLQIGLLTAIPWIAAAAGGILLPRFARTEQRSRSML
MAGYLVMATGMAIGAIAGHGVALLGFSLAAFMFFAMQSIIFNWLPSIMSGHMLAGSFGLLNCLGLCGGFLGPFILGAFED
RTGAATSGLWFAVALLIIGALVSLFLKSSSSPGSVSAKQAHGEKV
>Mature_444_residues
SAINEKAVNGTQLQRTHKKIYRHLMPLLIVAYIISFIDRTNIGMAKATMSVDIGLSATAFGLGAGLFFLTYAVLEIPSNL
FLTRIGARRWIARIMITWGILSCGMAFVTGPTSFYVMRLLLGAAEAGLYPGIIYYLTLWFGREERAKATGLFLLGVCLAN
IIGAPLGGLLLSLDGMSGWHGWQWMFFIEGLPAIALAFVVWRRLPDKPADARWLDSDDVQAINAVLAKEAEETRHTPSRF
SLKTALSTRVFLLLVLIYFTHQFSVYGLSYFLPGIIGSWGQLTPLQIGLLTAIPWIAAAAGGILLPRFARTEQRSRSMLM
AGYLVMATGMAIGAIAGHGVALLGFSLAAFMFFAMQSIIFNWLPSIMSGHMLAGSFGLLNCLGLCGGFLGPFILGAFEDR
TGAATSGLWFAVALLIIGALVSLFLKSSSSPGSVSAKQAHGEKV

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=419, Percent_Identity=36.0381861575179, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI1789152, Length=444, Percent_Identity=23.6486486486486, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI2367379, Length=293, Percent_Identity=26.2798634812287, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87082320, Length=426, Percent_Identity=23.7089201877934, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789515, Length=339, Percent_Identity=23.3038348082596, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321698, Length=351, Percent_Identity=28.2051282051282, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322025, Length=209, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=200, Percent_Identity=24, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319250, Length=263, Percent_Identity=20.1520912547529, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48079; Mature: 47947

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAINEKAVNGTQLQRTHKKIYRHLMPLLIVAYIISFIDRTNIGMAKATMSVDIGLSATA
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEECCCCHHH
FGLGAGLFFLTYAVLEIPSNLFLTRIGARRWIARIMITWGILSCGMAFVTGPTSFYVMRL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHH
LLGAAEAGLYPGIIYYLTLWFGREERAKATGLFLLGVCLANIIGAPLGGLLLSLDGMSGW
HHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCC
HGWQWMFFIEGLPAIALAFVVWRRLPDKPADARWLDSDDVQAINAVLAKEAEETRHTPSR
CCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCH
FSLKTALSTRVFLLLVLIYFTHQFSVYGLSYFLPGIIGSWGQLTPLQIGLLTAIPWIAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AGGILLPRFARTEQRSRSMLMAGYLVMATGMAIGAIAGHGVALLGFSLAAFMFFAMQSII
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FNWLPSIMSGHMLAGSFGLLNCLGLCGGFLGPFILGAFEDRTGAATSGLWFAVALLIIGA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LVSLFLKSSSSPGSVSAKQAHGEKV
HHHHHHHCCCCCCCCCHHHCCCCCC
>Mature Secondary Structure 
SAINEKAVNGTQLQRTHKKIYRHLMPLLIVAYIISFIDRTNIGMAKATMSVDIGLSATA
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEECCCCHHH
FGLGAGLFFLTYAVLEIPSNLFLTRIGARRWIARIMITWGILSCGMAFVTGPTSFYVMRL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHH
LLGAAEAGLYPGIIYYLTLWFGREERAKATGLFLLGVCLANIIGAPLGGLLLSLDGMSGW
HHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCC
HGWQWMFFIEGLPAIALAFVVWRRLPDKPADARWLDSDDVQAINAVLAKEAEETRHTPSR
CCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCH
FSLKTALSTRVFLLLVLIYFTHQFSVYGLSYFLPGIIGSWGQLTPLQIGLLTAIPWIAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AGGILLPRFARTEQRSRSMLMAGYLVMATGMAIGAIAGHGVALLGFSLAAFMFFAMQSII
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FNWLPSIMSGHMLAGSFGLLNCLGLCGGFLGPFILGAFEDRTGAATSGLWFAVALLIIGA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LVSLFLKSSSSPGSVSAKQAHGEKV
HHHHHHHCCCCCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]