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The map label for this gene is yedX [H]

Identifier: 238894706

GI number: 238894706

Start: 2590265

End: 2590591

Strand: Direct

Name: yedX [H]

Synonym: KP1_2712

Alternate gene names: 238894706

Gene position: 2590265-2590591 (Clockwise)

Preceding gene: 238894705

Following gene: 238894707

Centisome position: 49.35

GC content: 64.53

Gene sequence:

>327_bases
ATGAGCACCCTGAGCACCCATATTCTGGATATTTCCACCGGTACGCCGGCAGAAGGCGTAACGGTCAGCCTGAGCCGGGA
GGGCGAGACGCTGGCGAACCTGGTGACCAACGCCCAGGGGCGTATCGCCACCTTTAGCGCCGCGCCGCTGCCGGCGGGGC
ACTATTGCTTAACAGCGGAAACCGGGGCGTGGTTTGCCCGCGCCGGGCGCGAGAGCGTCTTTACCCGGGCGCAGATTGAT
TTTGTTATCGGCGAGGCGGCAGAGGACCATTTCCATCTGCCGTTTCTCATCGCCCCGGGCGGGTGGTCGACCTACCGCGG
CAGCTAA

Upstream 100 bases:

>100_bases
TGACGCGCCGGCTGCAGCATACCGCCGACGAAGAAGTGGCCGAGGCGCTTGCCCAGCTGCGAGAGATTACGATGTTAAGA
CTGGAAGGAGTGATTGGCGA

Downstream 100 bases:

>100_bases
GCGCGACTGCCCGCTGCCGGGCGGCGCTGCGCTTGCCCGGCCTGGATCGTAACGGAGCGGGTAGAGACAGCCCGTAGGCC
CGGTAAGGCGCAGCCGCCAC

Product: transthyretin-like protein

Products: NA

Alternate protein names: HIU hydrolase; HIUHase; Transthyretin-like protein; TLP [H]

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MSTLSTHILDISTGTPAEGVTVSLSREGETLANLVTNAQGRIATFSAAPLPAGHYCLTAETGAWFARAGRESVFTRAQID
FVIGEAAEDHFHLPFLIAPGGWSTYRGS

Sequences:

>Translated_108_residues
MSTLSTHILDISTGTPAEGVTVSLSREGETLANLVTNAQGRIATFSAAPLPAGHYCLTAETGAWFARAGRESVFTRAQID
FVIGEAAEDHFHLPFLIAPGGWSTYRGS
>Mature_107_residues
STLSTHILDISTGTPAEGVTVSLSREGETLANLVTNAQGRIATFSAAPLPAGHYCLTAETGAWFARAGRESVFTRAQIDF
VIGEAAEDHFHLPFLIAPGGWSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=113, Percent_Identity=36.283185840708, Blast_Score=72, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24652571, Length=110, Percent_Identity=35.4545454545455, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 11423; Mature: 11292

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00622 HTH_LUXR_1 ; PS00768 TRANSTHYRETIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLSTHILDISTGTPAEGVTVSLSREGETLANLVTNAQGRIATFSAAPLPAGHYCLTAE
CCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHCCCCCCEEEEECCCCCCCCEEEEEC
TGAWFARAGRESVFTRAQIDFVIGEAAEDHFHLPFLIAPGGWSTYRGS
CCCCEECCCCCHHEEEEEEEEEEECCCCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
STLSTHILDISTGTPAEGVTVSLSREGETLANLVTNAQGRIATFSAAPLPAGHYCLTAE
CCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHCCCCCCEEEEECCCCCCCCEEEEEC
TGAWFARAGRESVFTRAQIDFVIGEAAEDHFHLPFLIAPGGWSTYRGS
CCCCEECCCCCHHEEEEEEEEEEECCCCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]