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The map label for this gene is pcbC [H]

Identifier: 238894694

GI number: 238894694

Start: 2578744

End: 2579772

Strand: Reverse

Name: pcbC [H]

Synonym: KP1_2700

Alternate gene names: 238894694

Gene position: 2579772-2578744 (Counterclockwise)

Preceding gene: 238894698

Following gene: 238894693

Centisome position: 49.15

GC content: 62.68

Gene sequence:

>1029_bases
ATGAACGCGACCACCCTGCCGATTCTCGACCTGGCCCGCTACGCGGACCCCGCGGATAAAGCGGCCTTCCTGGCCGACCT
GCGTCATGCCGCCCGCGACATCGGCTTCTTCTATTTGATCAACCACGGTGTCGACGACGCGCTTCAATATGAAGTTCAGC
GCCAGTCCCAGCGTTTTTTTGCTCTCGATGAGGCGCAAAAACAGCAGGTGGCGATGATCCACTCCCCCCATTTTCGCGGC
TATAACCGCGCGGCCTCTGAGCTGACGCGCGGCCAGCCTGACTGGCGAGAACAGTTTGATATCGGCGCCGAACGTCCGGC
GCTAACCCTCAGCGACGACGCCCCGCGCTGGCAGCGCCTGCAGGGTCCGAATCTGTGGCCTGCCGCCCTGCCGTCGCTTA
AACCGGTATTACTTCACTGGCAACAGCAAATGACCCAGGTGGGCATCCGCCTGCTGCGCGCCTTTGCCGAAGCCCTGCAG
CTCCCGGAGAATGCTTTCGATCAGCTCTACGGCGAGAAACCCAACGAGCATATCAAACTGATCCGCTACCCCGGCCAGCA
GGAGACCCAAAGCAGCCAGGGCGTCGGCGCCCATAAAGATTCGGGGTTTCTCAGCTTCCTGCTGCAGGACGAGCAGAAAG
GACTGCAGGTAGAGGTCGCGCCTGGAGAATGGATCGACGCCGTGCCGCTGGCCGGCAGCTTTGTGGTCAATATTGGCGAA
CTGCTGGAGCTGGCGACCAACGGGTATTTGCGCGCTACCGTCCATCGCGTGGTGTCGCCGCCGGCGCAGCAGCAGCGCCT
CTCCATCGCCTTCTTCCTCGGCGCCCAGCTTGACGCGGTGGTGCCGGTTTACACCCTGCCGCCCGAGCTGGCGCGTGAAG
CGCGAGGGCCGGACAGCGACCCGCACAATCCGCTGCTGCGCGATGTCGGCTGGAATTATCTCAAGGGCCGTCTGCGTTCC
CATCCGGACGTGGCGGAACGCTACTATCAGGACGTGTTTCGCGAACGCGCCGAGCAATTGATCGTTTAA

Upstream 100 bases:

>100_bases
GTTCAGCCCCGGACAGAGGAAATCACCATGCGCTGCTGTTGTGCCCGAACCCAGAACCTGAATCTACCCATAACTTATTA
CCCCGTTTTCGGAGAACACA

Downstream 100 bases:

>100_bases
CCATAACTAAAAAGGAACACACCATGAAATATGCCGCTTTTAAACTGGCAGGGGTCGCACTGTCTCTTTCTCTGGTATGG
ACGTCTGCCCAGGCTGCCGC

Product: putative 2OG-Fe(II) oxygenase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNATTLPILDLARYADPADKAAFLADLRHAARDIGFFYLINHGVDDALQYEVQRQSQRFFALDEAQKQQVAMIHSPHFRG
YNRAASELTRGQPDWREQFDIGAERPALTLSDDAPRWQRLQGPNLWPAALPSLKPVLLHWQQQMTQVGIRLLRAFAEALQ
LPENAFDQLYGEKPNEHIKLIRYPGQQETQSSQGVGAHKDSGFLSFLLQDEQKGLQVEVAPGEWIDAVPLAGSFVVNIGE
LLELATNGYLRATVHRVVSPPAQQQRLSIAFFLGAQLDAVVPVYTLPPELAREARGPDSDPHNPLLRDVGWNYLKGRLRS
HPDVAERYYQDVFRERAEQLIV

Sequences:

>Translated_342_residues
MNATTLPILDLARYADPADKAAFLADLRHAARDIGFFYLINHGVDDALQYEVQRQSQRFFALDEAQKQQVAMIHSPHFRG
YNRAASELTRGQPDWREQFDIGAERPALTLSDDAPRWQRLQGPNLWPAALPSLKPVLLHWQQQMTQVGIRLLRAFAEALQ
LPENAFDQLYGEKPNEHIKLIRYPGQQETQSSQGVGAHKDSGFLSFLLQDEQKGLQVEVAPGEWIDAVPLAGSFVVNIGE
LLELATNGYLRATVHRVVSPPAQQQRLSIAFFLGAQLDAVVPVYTLPPELAREARGPDSDPHNPLLRDVGWNYLKGRLRS
HPDVAERYYQDVFRERAEQLIV
>Mature_342_residues
MNATTLPILDLARYADPADKAAFLADLRHAARDIGFFYLINHGVDDALQYEVQRQSQRFFALDEAQKQQVAMIHSPHFRG
YNRAASELTRGQPDWREQFDIGAERPALTLSDDAPRWQRLQGPNLWPAALPSLKPVLLHWQQQMTQVGIRLLRAFAEALQ
LPENAFDQLYGEKPNEHIKLIRYPGQQETQSSQGVGAHKDSGFLSFLLQDEQKGLQVEVAPGEWIDAVPLAGSFVVNIGE
LLELATNGYLRATVHRVVSPPAQQQRLSIAFFLGAQLDAVVPVYTLPPELAREARGPDSDPHNPLLRDVGWNYLKGRLRS
HPDVAERYYQDVFRERAEQLIV

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=290, Percent_Identity=25.1724137931034, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 38640; Mature: 38640

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATTLPILDLARYADPADKAAFLADLRHAARDIGFFYLINHGVDDALQYEVQRQSQRFF
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHEE
ALDEAQKQQVAMIHSPHFRGYNRAASELTRGQPDWREQFDIGAERPALTLSDDAPRWQRL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCEEECCCCCHHHHC
QGPNLWPAALPSLKPVLLHWQQQMTQVGIRLLRAFAEALQLPENAFDQLYGEKPNEHIKL
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEE
IRYPGQQETQSSQGVGAHKDSGFLSFLLQDEQKGLQVEVAPGEWIDAVPLAGSFVVNIGE
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHH
LLELATNGYLRATVHRVVSPPAQQQRLSIAFFLGAQLDAVVPVYTLPPELAREARGPDSD
HHHHHHCCHHHHHHHHHHCCCHHHHHHEEEEEECCCHHHCCCEEECCHHHHHHCCCCCCC
PHNPLLRDVGWNYLKGRLRSHPDVAERYYQDVFRERAEQLIV
CCCHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNATTLPILDLARYADPADKAAFLADLRHAARDIGFFYLINHGVDDALQYEVQRQSQRFF
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHEE
ALDEAQKQQVAMIHSPHFRGYNRAASELTRGQPDWREQFDIGAERPALTLSDDAPRWQRL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCEEECCCCCHHHHC
QGPNLWPAALPSLKPVLLHWQQQMTQVGIRLLRAFAEALQLPENAFDQLYGEKPNEHIKL
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEE
IRYPGQQETQSSQGVGAHKDSGFLSFLLQDEQKGLQVEVAPGEWIDAVPLAGSFVVNIGE
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHH
LLELATNGYLRATVHRVVSPPAQQQRLSIAFFLGAQLDAVVPVYTLPPELAREARGPDSD
HHHHHHCCHHHHHHHHHHCCCHHHHHHEEEEEECCCHHHCCCEEECCHHHHHHCCCCCCC
PHNPLLRDVGWNYLKGRLRSHPDVAERYYQDVFRERAEQLIV
CCCHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3130293 [H]