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The map label for this gene is yneH [H]

Identifier: 238894671

GI number: 238894671

Start: 2561257

End: 2562183

Strand: Direct

Name: yneH [H]

Synonym: KP1_2676

Alternate gene names: 238894671

Gene position: 2561257-2562183 (Clockwise)

Preceding gene: 238894670

Following gene: 238894672

Centisome position: 48.8

GC content: 60.84

Gene sequence:

>927_bases
GTGGCGACGGTTATCAATAATGCAATGCTGGAAGCCATTCTGGCAGAAATCAGGCCGCTGATTGGCCGCGGAAAAGTGGC
GGATTATATTCCGGCGCTGGCCAGCGTCAGCGGCGACAAGCTTGGTATCGCGATCAGTACGGTGGACGGTCAGCACTTTG
CCGCTGGCGATGCCCATGAACGTTTTTCCATCCAGTCAATCTCCAAGGTATTGAGCCTGGTGGTGGCCATGAACCACTAT
CAGGAGGAGGAGATCTGGCAGCGGGTGGGGAAAGATCCTTCCGGCCAGCCCTTTAACTCGCTTCTGCAGCTGGAGATCGA
GCAGGGCAAACCGCGCAACCCGTTTATCAACGCCGGGGCACTGGTGGTCTGCGACATGCTGCAGAGCCGGCTCAGCGCCC
CGCGTCAGCGGATGCTGGAGATTGTCCGCCGTCTGAGCGGCGTGGCCGATATCGCCTACGATCCGGTGGTGGCTCGCTCA
GAGTTTGAGCATTCGGCGCGCAACGCCGCCATCGCCTGGCTGATGAAATCCTTTGGTAACTTCCATAACGACGTCGCCAC
CGTGCTGCAGAACTATTTCCACTACTGTTCGCTGGAGATGAGCTGCGTTGAGCTGGCGCGAACCTTTCTGTTTCTCGCCG
ACCGCGGCATTGCCCCGCATCTCGACGCGCCGGTTATTGCGCCCATCCAGTCCAGCCAGGTGAATGCCCTGATGATGACC
AGCGGCATGTACCAGAACGCCGGTGAATTCGCCTGGCGCGTTGGCCTGCCGGCGAAATCGGGCGTCGGCGGCGGGATCGT
GGCGATTGTCCCGCAGGAGATGGCGATCGCCGTGTGGAGCCCGGAGCTTGACGACGCCGGGAACTCGCTGGCCGGCGTGG
CGATGCTGGAAAAACTAACTCAGCGGATGGGGAGGTCGGTGTTCTGA

Upstream 100 bases:

>100_bases
TCTGGAAAGACCGTCGCTAATCAACGTTAGCCCCTGACGACCGTCGTCCACGTCTGCTATACTCGCCCACCGAATTTTGA
TGGTGGGCAAGGAGCCGCGT

Downstream 100 bases:

>100_bases
TGGTCGATCAGGATCGCTTGTTTGCGCGCCTGGCGCGCTCGACGTTTCGCTCACGCTTCCGTCTGGGGGGGAAAGAGCGG
CAATATTGTCTCGATAAGGG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MATVINNAMLEAILAEIRPLIGRGKVADYIPALASVSGDKLGIAISTVDGQHFAAGDAHERFSIQSISKVLSLVVAMNHY
QEEEIWQRVGKDPSGQPFNSLLQLEIEQGKPRNPFINAGALVVCDMLQSRLSAPRQRMLEIVRRLSGVADIAYDPVVARS
EFEHSARNAAIAWLMKSFGNFHNDVATVLQNYFHYCSLEMSCVELARTFLFLADRGIAPHLDAPVIAPIQSSQVNALMMT
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPQEMAIAVWSPELDDAGNSLAGVAMLEKLTQRMGRSVF

Sequences:

>Translated_308_residues
MATVINNAMLEAILAEIRPLIGRGKVADYIPALASVSGDKLGIAISTVDGQHFAAGDAHERFSIQSISKVLSLVVAMNHY
QEEEIWQRVGKDPSGQPFNSLLQLEIEQGKPRNPFINAGALVVCDMLQSRLSAPRQRMLEIVRRLSGVADIAYDPVVARS
EFEHSARNAAIAWLMKSFGNFHNDVATVLQNYFHYCSLEMSCVELARTFLFLADRGIAPHLDAPVIAPIQSSQVNALMMT
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPQEMAIAVWSPELDDAGNSLAGVAMLEKLTQRMGRSVF
>Mature_307_residues
ATVINNAMLEAILAEIRPLIGRGKVADYIPALASVSGDKLGIAISTVDGQHFAAGDAHERFSIQSISKVLSLVVAMNHYQ
EEEIWQRVGKDPSGQPFNSLLQLEIEQGKPRNPFINAGALVVCDMLQSRLSAPRQRMLEIVRRLSGVADIAYDPVVARSE
FEHSARNAAIAWLMKSFGNFHNDVATVLQNYFHYCSLEMSCVELARTFLFLADRGIAPHLDAPVIAPIQSSQVNALMMTS
GMYQNAGEFAWRVGLPAKSGVGGGIVAIVPQEMAIAVWSPELDDAGNSLAGVAMLEKLTQRMGRSVF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=280, Percent_Identity=37.5, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI20336214, Length=294, Percent_Identity=34.3537414965986, Blast_Score=165, Evalue=4e-41,
Organism=Escherichia coli, GI1787804, Length=308, Percent_Identity=81.8181818181818, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI1786693, Length=286, Percent_Identity=39.8601398601399, Blast_Score=208, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17507019, Length=285, Percent_Identity=37.1929824561403, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI193204073, Length=304, Percent_Identity=36.1842105263158, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI193204075, Length=306, Percent_Identity=35.9477124183007, Blast_Score=180, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17532727, Length=284, Percent_Identity=35.5633802816901, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281363239, Length=286, Percent_Identity=37.7622377622378, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI281363241, Length=286, Percent_Identity=37.7622377622378, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24653162, Length=286, Percent_Identity=37.7622377622378, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24653156, Length=286, Percent_Identity=37.7622377622378, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24653158, Length=286, Percent_Identity=37.7622377622378, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24653164, Length=286, Percent_Identity=37.7622377622378, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI116008307, Length=286, Percent_Identity=37.7622377622378, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24653166, Length=286, Percent_Identity=37.7622377622378, Blast_Score=191, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33452; Mature: 33321

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVINNAMLEAILAEIRPLIGRGKVADYIPALASVSGDKLGIAISTVDGQHFAAGDAHE
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHH
RFSIQSISKVLSLVVAMNHYQEEEIWQRVGKDPSGQPFNSLLQLEIEQGKPRNPFINAGA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHEEHCCCCCCCCCCCCCCH
LVVCDMLQSRLSAPRQRMLEIVRRLSGVADIAYDPVVARSEFEHSARNAAIAWLMKSFGN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
FHNDVATVLQNYFHYCSLEMSCVELARTFLFLADRGIAPHLDAPVIAPIQSSQVNALMMT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCEEE
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPQEMAIAVWSPELDDAGNSLAGVAMLEKLT
CCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHH
QRMGRSVF
HHHCCCCC
>Mature Secondary Structure 
ATVINNAMLEAILAEIRPLIGRGKVADYIPALASVSGDKLGIAISTVDGQHFAAGDAHE
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHH
RFSIQSISKVLSLVVAMNHYQEEEIWQRVGKDPSGQPFNSLLQLEIEQGKPRNPFINAGA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHEEHCCCCCCCCCCCCCCH
LVVCDMLQSRLSAPRQRMLEIVRRLSGVADIAYDPVVARSEFEHSARNAAIAWLMKSFGN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
FHNDVATVLQNYFHYCSLEMSCVELARTFLFLADRGIAPHLDAPVIAPIQSSQVNALMMT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCEEE
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPQEMAIAVWSPELDDAGNSLAGVAMLEKLT
CCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHH
QRMGRSVF
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA