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The map label for this gene is eamA [H]

Identifier: 238894652

GI number: 238894652

Start: 2544374

End: 2545273

Strand: Direct

Name: eamA [H]

Synonym: KP1_2656

Alternate gene names: 238894652

Gene position: 2544374-2545273 (Clockwise)

Preceding gene: 238894649

Following gene: 238894656

Centisome position: 48.48

GC content: 61.44

Gene sequence:

>900_bases
ATGACGAGGAAAGATGGACTACTGGCGCTGCTGGTAGTGGTGGTGTGGGGGCTTAACTTTGTGGTGATTAAGCTGGGGTT
GCACAATATGCCGCCGCTGATGCTGGCGGGGCTGCGCTTTATGCTGGTCGCCTTCCCGGCGCTGCTGTTTGTCGCCCGGC
CAGCTATTCCGCTGCGCCTGCTGCTGGGCTATGGCCTGACCATAAGTTTCGGTCAGTTCGCCTTTCTGTTCTGCGCTATC
GGCCTGGGTATGCCGGCCGGGCTGGCCTCCCTTGTGCTGCAGGCGCAAGCCTTCTTCACCATCATCCTTGGCGCCTTCGT
CTTTGGCGAACGTCTGCAGGTCAAGCAGCTGGCGGGGATCGCCCTGGCGATCTTTGGCGTGTTGGTGCTGGTGGAGGGCA
GCCTTGGCGGGGAGCATGTGCCGCTGGTGGGCTTTATGCTGACCCTCGCGGCGGCGCTCAGCTGGGCCTGCGGCAATATT
TTCAACAAGAAAATCATGTCCCAGGCGAGCCGGCCGCCAATCATGTCGCTGGTGGTCTGGAGCGCGCTGATCCCGGTGCT
GCCGTTTATGCTGGCCTCATTGTTGATCGATGGCCCGCAGACCATGCTGGCGAGTCTGCAACACATCGATCTGCTAACGA
TACTGTCGCTGCTTTATCTGGCGTTTATCGCCACTATCGTCGGCTATGGCATCTGGGGATCGCTGCTGGGGCGGTATGAA
ACCTGGCGGGTGGCGCCGCTGTCGCTGCTGGTGCCGGTGGTGGGAATGGCCAGCGCTGCGCTGCTGCTCGGGGAGACGCT
GAGCGGACTGCAGCTCACCGGGGCGGTGCTGATTATGGCCGGGCTCTACATTAATATCTTTGGCTTACGTTTGGTGCGGC
CTGGCATGGCGCGCGGATAA

Upstream 100 bases:

>100_bases
CACTTCCGGGCCTGCCAAAAATAATGATCTATCCCGGCGGCCGCTTTTTCGCTACTTTGATTTTGTTCACAAAAATTCCA
ATAACGACAGAGGCAGGGGT

Downstream 100 bases:

>100_bases
AAAAAAGCCCCGGAGACGGGGCTATACACAATTATGCGTGTAATGGCATCACAGGTCGTGCTGCTGATAGTACGGCACGC
CAAGTTCGTCAGATTTATCA

Product: O-acetylserine/cysteine export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTRKDGLLALLVVVVWGLNFVVIKLGLHNMPPLMLAGLRFMLVAFPALLFVARPAIPLRLLLGYGLTISFGQFAFLFCAI
GLGMPAGLASLVLQAQAFFTIILGAFVFGERLQVKQLAGIALAIFGVLVLVEGSLGGEHVPLVGFMLTLAAALSWACGNI
FNKKIMSQASRPPIMSLVVWSALIPVLPFMLASLLIDGPQTMLASLQHIDLLTILSLLYLAFIATIVGYGIWGSLLGRYE
TWRVAPLSLLVPVVGMASAALLLGETLSGLQLTGAVLIMAGLYINIFGLRLVRPGMARG

Sequences:

>Translated_299_residues
MTRKDGLLALLVVVVWGLNFVVIKLGLHNMPPLMLAGLRFMLVAFPALLFVARPAIPLRLLLGYGLTISFGQFAFLFCAI
GLGMPAGLASLVLQAQAFFTIILGAFVFGERLQVKQLAGIALAIFGVLVLVEGSLGGEHVPLVGFMLTLAAALSWACGNI
FNKKIMSQASRPPIMSLVVWSALIPVLPFMLASLLIDGPQTMLASLQHIDLLTILSLLYLAFIATIVGYGIWGSLLGRYE
TWRVAPLSLLVPVVGMASAALLLGETLSGLQLTGAVLIMAGLYINIFGLRLVRPGMARG
>Mature_298_residues
TRKDGLLALLVVVVWGLNFVVIKLGLHNMPPLMLAGLRFMLVAFPALLFVARPAIPLRLLLGYGLTISFGQFAFLFCAIG
LGMPAGLASLVLQAQAFFTIILGAFVFGERLQVKQLAGIALAIFGVLVLVEGSLGGEHVPLVGFMLTLAAALSWACGNIF
NKKIMSQASRPPIMSLVVWSALIPVLPFMLASLLIDGPQTMLASLQHIDLLTILSLLYLAFIATIVGYGIWGSLLGRYET
WRVAPLSLLVPVVGMASAALLLGETLSGLQLTGAVLIMAGLYINIFGLRLVRPGMARG

Specific function: May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O- acetyl-L-serine (OAS)), and for other amino acids and their metabolites [H]

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI87081929, Length=290, Percent_Identity=81.3793103448276, Blast_Score=458, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 31840; Mature: 31708

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKDGLLALLVVVVWGLNFVVIKLGLHNMPPLMLAGLRFMLVAFPALLFVARPAIPLRL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LLGYGLTISFGQFAFLFCAIGLGMPAGLASLVLQAQAFFTIILGAFVFGERLQVKQLAGI
HHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAIFGVLVLVEGSLGGEHVPLVGFMLTLAAALSWACGNIFNKKIMSQASRPPIMSLVVW
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SALIPVLPFMLASLLIDGPQTMLASLQHIDLLTILSLLYLAFIATIVGYGIWGSLLGRYE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TWRVAPLSLLVPVVGMASAALLLGETLSGLQLTGAVLIMAGLYINIFGLRLVRPGMARG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRKDGLLALLVVVVWGLNFVVIKLGLHNMPPLMLAGLRFMLVAFPALLFVARPAIPLRL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LLGYGLTISFGQFAFLFCAIGLGMPAGLASLVLQAQAFFTIILGAFVFGERLQVKQLAGI
HHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAIFGVLVLVEGSLGGEHVPLVGFMLTLAAALSWACGNIFNKKIMSQASRPPIMSLVVW
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SALIPVLPFMLASLLIDGPQTMLASLQHIDLLTILSLLYLAFIATIVGYGIWGSLLGRYE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TWRVAPLSLLVPVVGMASAALLLGETLSGLQLTGAVLIMAGLYINIFGLRLVRPGMARG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 10844694 [H]