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The map label for this gene is livM [C]

Identifier: 238894647

GI number: 238894647

Start: 2539756

End: 2540829

Strand: Direct

Name: livM [C]

Synonym: KP1_2651

Alternate gene names: 238894647

Gene position: 2539756-2540829 (Clockwise)

Preceding gene: 238894646

Following gene: 238894648

Centisome position: 48.39

GC content: 63.59

Gene sequence:

>1074_bases
ATGAGCCAACCAATCACCTTAACGCTGGCGCAGCGCGCGCCGCGGCCTCTGCGCTGGCTGGGGATCCTGCTGGTGCTGGG
GCTGCTGTGTATGCCATTCCTGGCGCTGCTGCCGGCCTCGCATCCGCTGGCGGTGCCGAGCTGGCTGCTGACGCTGAGCG
GCAAAATCCTCTGCTACGCCATTGTGGCGGTGGCGCTGGATCTGGTCTGGGGCTACGCGGGTATGCTGTCGCTGGGGCAC
GGGATTTTCTTTGCCCTCGGCGGGTACGCCATGGGGATGTACCTGATGCGCCAGGCGGCGGGGGACGGTCTACCGGCGTT
TATGTCTTTTCTCTCCTGGAGCGAGCTGCCCTGGTTCTGGTGGGGCACGCAGCATTTCGCCTGGGCGATGGCGCTGGTGG
TGCTGGTTCCCGGTCTGCTGGCCCTGGTTTTCGGCTGGTTTGCCTTTCGCTCGAAGATCAAAGGGGTCTATTTCTCGATC
ATGACCCAGGCCCTGACCTATGCCGGTATGCTGCTGTTCTTTCGCAACGAGACCGGGTTTGGCGGGAATAACGGCTTCAC
CGGTTTTACCACGCTGCTGGGCTTTCCTGTCACCGCCACCGGCACCCGCGCCAGCCTGTTTATGGCCACGGTTTTGCTGC
TGTTGCTGACGCTGTGGCTGGGCGCGGCGCTGGCGCAGAGTAAGTTTGGCCGGATCCTCACCGCGGTGCGTGACGCCGAA
AACCGACTGATGTTCTGCGGGTACGACCCGCGCGGCTTCAAGCTGCTGGTGTGGACGCTGTCGGCGGTGCTCTGCGGTCT
GGCGGGGGCGTTATATGTCCCGCAGGTGGGGATCATCAACCCCAGCGAAATGTCGCCGACCAACTCCATCGAGGCCGCCA
TCTGGGTGGCGCTCGGCGGGCGCGGCACCCTGATTGGCCCGGTGCTTGGCGCCGGATTGGTCAACGGTGCGAAAAGCATT
TTCACCGTGGCGATGCCAGAGTACTGGCAGCTGTTTCTCGGCCTCATCTTCATCATTGTGACCCTGTTTTTACCCCGCGG
GGTGATGGGCCTGCTGCGTCGAGGAGACCGCTAA

Upstream 100 bases:

>100_bases
GCGCTGTGCTGGGCAAGATCCTGATCCTGGTGATGATTATTCTGTTTATTCAGAAACGCCCGCAGGGTCTGTTCGCGCTG
AAAGGGAGGGTTATTGACTA

Downstream 100 bases:

>100_bases
TGCAACCGGATGAAGGACTATTTACCCGCCAGCTGCCCGGCGATCGCTTTCGCGAACAAACCGATCCGGTGCTGCAGCTG
GAGAACATCAACGTCAGCTT

Product: high-affinity branched-chain amino acid ABC transport system permease component

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: Urea ABC Transporter Permease Protein UrtC; Branched-Chain Amino Acid ABC Transporter Permease Protein; ABC Transporter Permease Protein; Urea ABC Transporter Permease UrtC; Amino Acid Or Sugar ABC Transport System Permease Protein; Branched Chain Amino Acid ABC Transporter Permease; Branched-Chain Amino Acid Transport System Permease Protein; Branched-Chain Amino Acid ABC Transporter Permease; ABC Transporter ; ABC Transporter Permease; ABC Transporter; Branched-Chain Amino Acid Transporter; Urea ABC Transporter Permease; ABC-Type Transport System Permease Protein; Permease Of ABC Transporter; ABC Transporter Membrane Spanning Protein; Urea Or Short-Chain Amide ABC Transporter Permease Protein; Amide-Urea Transport System Permease Protein; Branched-Chain Amino Acid Inner-Membrane Translocator; Branched Chain Amino Acid ABC Transporter Permease Protein; Amide-Urea Transporter Permease Protein; Permease Abc Transporter Protein; Transmembrane Component Of ABC Transporter; High-Affinity Branched-Chain Amino Acid Transport System; Urea/Short Chain-Amide ABC Transporter Permease Protein; Urea ABC Transporter Permease Protein; ABC Transporter Related Protein; ABC Transporter Membrane Protein; ABC-Type Urea Transport System Permease Protein II; Urea Transport System Permease Protein; ABC Transporter Inner-Membrane Translocator; ABC Transporter-Like Protein; Integral Membrane Protein; Urea ABC Transporter Inner-Membrane Subunit UrtC; Permease Component Of ABC Transporter Protein; ABC Branched Amino Acid Transporter Permease Component; Branched-Chain Amino Acid Transport System Permease; Amino Acid/Amide ABC Transporter Membrane HAAT Family; Permease Protein Of ABC Transporter; Urea Transport System Permease Component Protein; Permease Component Of ABC Transporter; Urea Or Short-Chain Amide ABC Transporter; Permease Transporter Transmembrane Protein; Urea ABC Transport Permease Component UrtC

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSQPITLTLAQRAPRPLRWLGILLVLGLLCMPFLALLPASHPLAVPSWLLTLSGKILCYAIVAVALDLVWGYAGMLSLGH
GIFFALGGYAMGMYLMRQAAGDGLPAFMSFLSWSELPWFWWGTQHFAWAMALVVLVPGLLALVFGWFAFRSKIKGVYFSI
MTQALTYAGMLLFFRNETGFGGNNGFTGFTTLLGFPVTATGTRASLFMATVLLLLLTLWLGAALAQSKFGRILTAVRDAE
NRLMFCGYDPRGFKLLVWTLSAVLCGLAGALYVPQVGIINPSEMSPTNSIEAAIWVALGGRGTLIGPVLGAGLVNGAKSI
FTVAMPEYWQLFLGLIFIIVTLFLPRGVMGLLRRGDR

Sequences:

>Translated_357_residues
MSQPITLTLAQRAPRPLRWLGILLVLGLLCMPFLALLPASHPLAVPSWLLTLSGKILCYAIVAVALDLVWGYAGMLSLGH
GIFFALGGYAMGMYLMRQAAGDGLPAFMSFLSWSELPWFWWGTQHFAWAMALVVLVPGLLALVFGWFAFRSKIKGVYFSI
MTQALTYAGMLLFFRNETGFGGNNGFTGFTTLLGFPVTATGTRASLFMATVLLLLLTLWLGAALAQSKFGRILTAVRDAE
NRLMFCGYDPRGFKLLVWTLSAVLCGLAGALYVPQVGIINPSEMSPTNSIEAAIWVALGGRGTLIGPVLGAGLVNGAKSI
FTVAMPEYWQLFLGLIFIIVTLFLPRGVMGLLRRGDR
>Mature_356_residues
SQPITLTLAQRAPRPLRWLGILLVLGLLCMPFLALLPASHPLAVPSWLLTLSGKILCYAIVAVALDLVWGYAGMLSLGHG
IFFALGGYAMGMYLMRQAAGDGLPAFMSFLSWSELPWFWWGTQHFAWAMALVVLVPGLLALVFGWFAFRSKIKGVYFSIM
TQALTYAGMLLFFRNETGFGGNNGFTGFTTLLGFPVTATGTRASLFMATVLLLLLTLWLGAALAQSKFGRILTAVRDAEN
RLMFCGYDPRGFKLLVWTLSAVLCGLAGALYVPQVGIINPSEMSPTNSIEAAIWVALGGRGTLIGPVLGAGLVNGAKSIF
TVAMPEYWQLFLGLIFIIVTLFLPRGVMGLLRRGDR

Specific function: Part Of The Binding-Protein-Dependent Transport System For Branched-Chain Amino Acids. Probably Responsible For The Translocation Of The Substrates Across The Membrane. [C]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789865, Length=336, Percent_Identity=25, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38716; Mature: 38585

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPITLTLAQRAPRPLRWLGILLVLGLLCMPFLALLPASHPLAVPSWLLTLSGKILCYA
CCCCEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHH
IVAVALDLVWGYAGMLSLGHGIFFALGGYAMGMYLMRQAAGDGLPAFMSFLSWSELPWFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
WGTQHFAWAMALVVLVPGLLALVFGWFAFRSKIKGVYFSIMTQALTYAGMLLFFRNETGF
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
GGNNGFTGFTTLLGFPVTATGTRASLFMATVLLLLLTLWLGAALAQSKFGRILTAVRDAE
CCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NRLMFCGYDPRGFKLLVWTLSAVLCGLAGALYVPQVGIINPSEMSPTNSIEAAIWVALGG
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECC
RGTLIGPVLGAGLVNGAKSIFTVAMPEYWQLFLGLIFIIVTLFLPRGVMGLLRRGDR
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQPITLTLAQRAPRPLRWLGILLVLGLLCMPFLALLPASHPLAVPSWLLTLSGKILCYA
CCCEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHH
IVAVALDLVWGYAGMLSLGHGIFFALGGYAMGMYLMRQAAGDGLPAFMSFLSWSELPWFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
WGTQHFAWAMALVVLVPGLLALVFGWFAFRSKIKGVYFSIMTQALTYAGMLLFFRNETGF
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
GGNNGFTGFTTLLGFPVTATGTRASLFMATVLLLLLTLWLGAALAQSKFGRILTAVRDAE
CCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NRLMFCGYDPRGFKLLVWTLSAVLCGLAGALYVPQVGIINPSEMSPTNSIEAAIWVALGG
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECC
RGTLIGPVLGAGLVNGAKSIFTVAMPEYWQLFLGLIFIIVTLFLPRGVMGLLRRGDR
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA