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The map label for this gene is tqsA [H]

Identifier: 238894583

GI number: 238894583

Start: 2482413

End: 2483447

Strand: Reverse

Name: tqsA [H]

Synonym: KP1_2582

Alternate gene names: 238894583

Gene position: 2483447-2482413 (Counterclockwise)

Preceding gene: 238894586

Following gene: 238894582

Centisome position: 47.32

GC content: 56.43

Gene sequence:

>1035_bases
ATGGCTAAACCCATTATTACACTTAACGGATTAAAGATGGTCATCATGTTGGGCATGCTGGTGATCATCCTTACCGGCAT
TCGCTTTGCGGCGGACATAATCGTCCCGTTTATCCTGGCGCTTTTTCTGGCGGTGATCATCAATCCTCTGGTCCAGCTAC
TGGTCCGCTGCCGGGTGCCGCGCGTGCTGGCGATCTCGCTACTGATTGGCCTGATTGTTATGTTAGCCATTGTGCTGCTG
GCCTCGCTGGGGACCTCGCTCAACGAGCTGGCGCGCACCCTGCCGCAGTATCGCAACTATCTCTATGAGCCGATGCAAAC
CATCGCGCCCTGGCTGCAGCGTATGGGATTCACCGTTTCGGTGGTCGAGCTCAATAAGTACATCGACCCTAACGCCGTAA
TGACCCTGGTCACCAGCCTGCTCACTCAGCTGTCGAACGCCATGTCCTCCATTTTTCTGCTGCTGCTGACGGTGGTGTTT
ATGCTGCTGGAGGTGCCGCAGCTTCCCGCTAAGCTGCAGCAGTTAATGTCCAGACCAGTAGAAGGCATGGGCGCCATCCA
GCGGGCCATCGACAGCGTATCGCATTATCTGGTGCTGAAAACTGCGATAAGCCTGATCACCGGCCTGGTGGTCTGGGGCA
TGCTGGTGCTGCTGGATGTGCGCTTCGCCTTTATGTGGGGGCTACTGGCCTTCGCGCTGAACTATATTCCCAATATCGGT
TCCGTGCTGGCGGCCATTCCGCCGATCCTGCAGGTGCTGGTGTTCGGTGGTCTGTACGAGGCGCTGGTAGTGCTGGCCGG
CTACCTGATCGTCAACCTGGTATTCGGCAATATTCTCGAACCTCGTATCATGGGGCGCGGGCTGGGCCTCTCGACGCTGG
TGGTATTCCTGTCCTTAATCTTCTGGGGATGGTTGCTGGGTCCGGTTGGCATGCTGCTCTCGGTGCCGTTGACGATTATC
GTCAAAATTGCCCTCGAGCAGACCAGCGGCGGGCAGAGTATCGCTTTCTTATTAAGCGATGTCAGTAAACAGTAG

Upstream 100 bases:

>100_bases
GCCGCGGTTTTTGTTCAATGCGTTTGTTCTGCAAAAAAGCGTCATTATGCTAATGTAACGCAACCTGTTAATAGGCAAGG
AAGTTTGAGGTCGGGATCCT

Downstream 100 bases:

>100_bases
TCCTTCCGCAGGCCGGCGCTTCGCCGGCCTGCTCCCTGCCCTACACTCTCTCCGTAGACCACTACGCCTTATGTATTATT
GATCCGCATCACAAACGTTG

Product: putative transport protein

Products: NA

Alternate protein names: Transport of quorum-sensing signal protein [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MAKPIITLNGLKMVIMLGMLVIILTGIRFAADIIVPFILALFLAVIINPLVQLLVRCRVPRVLAISLLIGLIVMLAIVLL
ASLGTSLNELARTLPQYRNYLYEPMQTIAPWLQRMGFTVSVVELNKYIDPNAVMTLVTSLLTQLSNAMSSIFLLLLTVVF
MLLEVPQLPAKLQQLMSRPVEGMGAIQRAIDSVSHYLVLKTAISLITGLVVWGMLVLLDVRFAFMWGLLAFALNYIPNIG
SVLAAIPPILQVLVFGGLYEALVVLAGYLIVNLVFGNILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTII
VKIALEQTSGGQSIAFLLSDVSKQ

Sequences:

>Translated_344_residues
MAKPIITLNGLKMVIMLGMLVIILTGIRFAADIIVPFILALFLAVIINPLVQLLVRCRVPRVLAISLLIGLIVMLAIVLL
ASLGTSLNELARTLPQYRNYLYEPMQTIAPWLQRMGFTVSVVELNKYIDPNAVMTLVTSLLTQLSNAMSSIFLLLLTVVF
MLLEVPQLPAKLQQLMSRPVEGMGAIQRAIDSVSHYLVLKTAISLITGLVVWGMLVLLDVRFAFMWGLLAFALNYIPNIG
SVLAAIPPILQVLVFGGLYEALVVLAGYLIVNLVFGNILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTII
VKIALEQTSGGQSIAFLLSDVSKQ
>Mature_343_residues
AKPIITLNGLKMVIMLGMLVIILTGIRFAADIIVPFILALFLAVIINPLVQLLVRCRVPRVLAISLLIGLIVMLAIVLLA
SLGTSLNELARTLPQYRNYLYEPMQTIAPWLQRMGFTVSVVELNKYIDPNAVMTLVTSLLTQLSNAMSSIFLLLLTVVFM
LLEVPQLPAKLQQLMSRPVEGMGAIQRAIDSVSHYLVLKTAISLITGLVVWGMLVLLDVRFAFMWGLLAFALNYIPNIGS
VLAAIPPILQVLVFGGLYEALVVLAGYLIVNLVFGNILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIV
KIALEQTSGGQSIAFLLSDVSKQ

Specific function: Controls the transport of the quorum-sensing signal AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms [H]

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1787885, Length=344, Percent_Identity=81.6860465116279, Blast_Score=513, Evalue=1e-147,
Organism=Escherichia coli, GI87082271, Length=339, Percent_Identity=46.6076696165192, Blast_Score=294, Evalue=7e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 37547; Mature: 37416

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPIITLNGLKMVIMLGMLVIILTGIRFAADIIVPFILALFLAVIINPLVQLLVRCRVP
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RVLAISLLIGLIVMLAIVLLASLGTSLNELARTLPQYRNYLYEPMQTIAPWLQRMGFTVS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
VVELNKYIDPNAVMTLVTSLLTQLSNAMSSIFLLLLTVVFMLLEVPQLPAKLQQLMSRPV
EHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCH
EGMGAIQRAIDSVSHYLVLKTAISLITGLVVWGMLVLLDVRFAFMWGLLAFALNYIPNIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
SVLAAIPPILQVLVFGGLYEALVVLAGYLIVNLVFGNILEPRIMGRGLGLSTLVVFLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FWGWLLGPVGMLLSVPLTIIVKIALEQTSGGQSIAFLLSDVSKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AKPIITLNGLKMVIMLGMLVIILTGIRFAADIIVPFILALFLAVIINPLVQLLVRCRVP
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RVLAISLLIGLIVMLAIVLLASLGTSLNELARTLPQYRNYLYEPMQTIAPWLQRMGFTVS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
VVELNKYIDPNAVMTLVTSLLTQLSNAMSSIFLLLLTVVFMLLEVPQLPAKLQQLMSRPV
EHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCH
EGMGAIQRAIDSVSHYLVLKTAISLITGLVVWGMLVLLDVRFAFMWGLLAFALNYIPNIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
SVLAAIPPILQVLVFGGLYEALVVLAGYLIVNLVFGNILEPRIMGRGLGLSTLVVFLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FWGWLLGPVGMLLSVPLTIIVKIALEQTSGGQSIAFLLSDVSKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]