Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 238894442

GI number: 238894442

Start: 2334618

End: 2335553

Strand: Reverse

Name: nahR [H]

Synonym: KP1_2430

Alternate gene names: 238894442

Gene position: 2335553-2334618 (Counterclockwise)

Preceding gene: 238894445

Following gene: 238894440

Centisome position: 44.5

GC content: 62.39

Gene sequence:

>936_bases
TTGATTATCATAATGAACAAAATCATTGAAAATGATTTTAGTCGTATCGATCTGAATCTGTTGACAGTCTTGATGGTGCT
GTACCGCGAAGGGAGCGTCACCCGCACCGCAGAGGTGCTCCATCTTGGCCAGCCGGCTATCAGCGGGGCGCTGAAACGGC
TGCGAGAGATGTTTGACGACCCGCTGTTCGTGCGCAGCGCCAGAGGCATGCTGCCGACGCCGCGGGCGCAAGCGCTGATG
ACCGACCTGCAGCCGCTGATGGAAAACCTGCATTCGGCGATGTTTGGCGCCGCAGAGTTCGTCCCGGCGCGCGCGCAGCA
GCTTTTTCGCATCGGCCTCAGCGACTGGAGCGAACACTGGCTGATGCCCCCGCTGTTACCCGGGCTGATGCAGGAGGCGC
CCGGAGTCTCACTGCAGTCGATAGCCGCCGACCCCTTCCAGGTTCGCCAGTTGCTGGAGGAGGAGCGCATTGATGTCGCG
GTGTCTGTCAACAAACAGAGCCGTGGGGAGATCGTCAGCGAGCCGGTGATGTCCATGGGAGTCACCACCCTGTGGTCGCC
GCAGCAGATCCCCTGCCGCGGGCCGCTGTCGGTGAGCGACATTGTCGCCTGGGAACATGTGATGGTGGCCTATCGCGAAA
CCGGCCACGGTGAAATTGACCGCCAGCTCGCCAGCCAGGGACTCGCGCGGCGCGTGCGCTTTGCCACGCAGAATTTCTCC
ACCTTTCCCCTGCTGCTGACCACCCTGCCGCTGTTCGCCACCGTCCCGCAGGGGCTGGCGCAGCGCTGGCAGGCGCAGTA
TGCGCTGCGCGCGGACGCTCCGCCGGTAGCGTATCCGGAATTTACGCTGTGCATTTTGCGGCACAAACGGAGGGCGCAGG
ATCCGGCGCTGAACTGGCTGGTGACGATGTTAAAACAGGCCATGCGCGGCCAATAA

Upstream 100 bases:

>100_bases
CGCCTGTCTGGTAAGTTTGCATCACTCCCTCCGCGCGCATTGCGCTGGTTGATTTATCGGGGTGATATTCACTATGCTGC
CGGGATAACCCACATTCAAA

Downstream 100 bases:

>100_bases
CCGGGCCGATGCCCCGGCATCAGGCCTCGCTGTGCGGGGGTTGCAGCACACGCCTGCTCCAGTCATAAAACGCGCGCACC
GCCGGCGGCAGATAGCGGTT

Product: putative LysR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MIIIMNKIIENDFSRIDLNLLTVLMVLYREGSVTRTAEVLHLGQPAISGALKRLREMFDDPLFVRSARGMLPTPRAQALM
TDLQPLMENLHSAMFGAAEFVPARAQQLFRIGLSDWSEHWLMPPLLPGLMQEAPGVSLQSIAADPFQVRQLLEEERIDVA
VSVNKQSRGEIVSEPVMSMGVTTLWSPQQIPCRGPLSVSDIVAWEHVMVAYRETGHGEIDRQLASQGLARRVRFATQNFS
TFPLLLTTLPLFATVPQGLAQRWQAQYALRADAPPVAYPEFTLCILRHKRRAQDPALNWLVTMLKQAMRGQ

Sequences:

>Translated_311_residues
MIIIMNKIIENDFSRIDLNLLTVLMVLYREGSVTRTAEVLHLGQPAISGALKRLREMFDDPLFVRSARGMLPTPRAQALM
TDLQPLMENLHSAMFGAAEFVPARAQQLFRIGLSDWSEHWLMPPLLPGLMQEAPGVSLQSIAADPFQVRQLLEEERIDVA
VSVNKQSRGEIVSEPVMSMGVTTLWSPQQIPCRGPLSVSDIVAWEHVMVAYRETGHGEIDRQLASQGLARRVRFATQNFS
TFPLLLTTLPLFATVPQGLAQRWQAQYALRADAPPVAYPEFTLCILRHKRRAQDPALNWLVTMLKQAMRGQ
>Mature_311_residues
MIIIMNKIIENDFSRIDLNLLTVLMVLYREGSVTRTAEVLHLGQPAISGALKRLREMFDDPLFVRSARGMLPTPRAQALM
TDLQPLMENLHSAMFGAAEFVPARAQQLFRIGLSDWSEHWLMPPLLPGLMQEAPGVSLQSIAADPFQVRQLLEEERIDVA
VSVNKQSRGEIVSEPVMSMGVTTLWSPQQIPCRGPLSVSDIVAWEHVMVAYRETGHGEIDRQLASQGLARRVRFATQNFS
TFPLLLTTLPLFATVPQGLAQRWQAQYALRADAPPVAYPEFTLCILRHKRRAQDPALNWLVTMLKQAMRGQ

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=293, Percent_Identity=24.9146757679181, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786820, Length=304, Percent_Identity=20.7236842105263, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34961; Mature: 34961

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIIMNKIIENDFSRIDLNLLTVLMVLYREGSVTRTAEVLHLGQPAISGALKRLREMFDD
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCC
PLFVRSARGMLPTPRAQALMTDLQPLMENLHSAMFGAAEFVPARAQQLFRIGLSDWSEHW
CHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LMPPLLPGLMQEAPGVSLQSIAADPFQVRQLLEEERIDVAVSVNKQSRGEIVSEPVMSMG
CCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHC
VTTLWSPQQIPCRGPLSVSDIVAWEHVMVAYRETGHGEIDRQLASQGLARRVRFATQNFS
CHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
TFPLLLTTLPLFATVPQGLAQRWQAQYALRADAPPVAYPEFTLCILRHKRRAQDPALNWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
VTMLKQAMRGQ
HHHHHHHHCCC
>Mature Secondary Structure
MIIIMNKIIENDFSRIDLNLLTVLMVLYREGSVTRTAEVLHLGQPAISGALKRLREMFDD
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCC
PLFVRSARGMLPTPRAQALMTDLQPLMENLHSAMFGAAEFVPARAQQLFRIGLSDWSEHW
CHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LMPPLLPGLMQEAPGVSLQSIAADPFQVRQLLEEERIDVAVSVNKQSRGEIVSEPVMSMG
CCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHC
VTTLWSPQQIPCRGPLSVSDIVAWEHVMVAYRETGHGEIDRQLASQGLARRVRFATQNFS
CHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
TFPLLLTTLPLFATVPQGLAQRWQAQYALRADAPPVAYPEFTLCILRHKRRAQDPALNWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
VTMLKQAMRGQ
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]