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The map label for this gene is ycjZ [C]

Identifier: 238894388

GI number: 238894388

Start: 2273118

End: 2274002

Strand: Reverse

Name: ycjZ [C]

Synonym: KP1_2371

Alternate gene names: 238894388

Gene position: 2274002-2273118 (Counterclockwise)

Preceding gene: 238894392

Following gene: 238894381

Centisome position: 43.33

GC content: 56.84

Gene sequence:

>885_bases
ATGGCGAAACGGGAAAACTATAATGACCTCTATCTGTTTATGCAGGTGGTGCGGGAAGGCAGTTTTACCGCCGCAGCGCA
ACGACTTGGCCTGGCGCAGTCCGGGGTAAGCCGTGCGGTTCGTGAACTTGAAGAGCGGCTGGGCGTTCAGCTTCTGGTGC
GTACCACCCGCCGGTTGTCGCTCACTCAGGCGGGTGAGCAGCTCTATCACAATGTCGAATCCGGTTTCGACGCCTTAGAT
ATGGGACTCGCCACGCTGGCCCACTATCGTCAAACGCCCTCCGGTACGGTACGCATCAATGCCAGCCAGCATGCCATTGA
TAAAGTCCTGCTGCCGAAGCTGGCAGTATTTAAACAACGCTATCCCGATATCAGACTGGAACTGATCAGCGAAAGCCGGT
TTGTCGATATTATTGCGCAGCGATTTGATGCGGGCGTGCGTCTGGGCCCGGAAGTCGGAAGCGGCATGATTGCGGTACGC
ATTTCGCCCGATATGGAGATGGCGGTGGTGGGTACCCCGGAACATTTTCGCCGCTACGGCTTTCCACAAACGCCCGCCGA
TTTAGTCGCCCACCCCTGCATCGCTTATCAGTTCGGCGACGGTAGCCTTTACGCCTGGGAACTTAATGTGGATGGCAAAA
AAATCACCCACCCGCCTCAGGGACAGTGGGCTTTCGCCGATAGCTATATGGAGGCCAAAGCGGCGAGGCTCGGTCTGGGG
CTGGCCTATGTCCCGGAAGAGCTGATTACCGACGATCTAGCCCAGGGCACACTTATCCGGGTGCTCCAGCGTTATAGCCA
GCGTCTGGAAGGTTCATATCTCTATTACCCGCACCGCAATGTGTCGCCCGCGCTGAGAGCGGTCATTGATACATTGCGAA
TGTAG

Upstream 100 bases:

>100_bases
GCTTAGTGTAGCCAGCAGTAATGGTTCTGATTAGAGGCTGAAAAATGCTAAAATTAATACCATATTGTTCTAAATGGCAT
CTGGGTGACGAGGCGGGAGA

Downstream 100 bases:

>100_bases
CTGAGGTTGCCTGCAGGCAGCAGGCAACCGGTAGCGGCCGGTGACTGGCGCTGTGCTCAGCATTTTCACTCATTTCCGAC
CCAGGCCACACAGGCCCTGA

Product: putative LysR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MAKRENYNDLYLFMQVVREGSFTAAAQRLGLAQSGVSRAVRELEERLGVQLLVRTTRRLSLTQAGEQLYHNVESGFDALD
MGLATLAHYRQTPSGTVRINASQHAIDKVLLPKLAVFKQRYPDIRLELISESRFVDIIAQRFDAGVRLGPEVGSGMIAVR
ISPDMEMAVVGTPEHFRRYGFPQTPADLVAHPCIAYQFGDGSLYAWELNVDGKKITHPPQGQWAFADSYMEAKAARLGLG
LAYVPEELITDDLAQGTLIRVLQRYSQRLEGSYLYYPHRNVSPALRAVIDTLRM

Sequences:

>Translated_294_residues
MAKRENYNDLYLFMQVVREGSFTAAAQRLGLAQSGVSRAVRELEERLGVQLLVRTTRRLSLTQAGEQLYHNVESGFDALD
MGLATLAHYRQTPSGTVRINASQHAIDKVLLPKLAVFKQRYPDIRLELISESRFVDIIAQRFDAGVRLGPEVGSGMIAVR
ISPDMEMAVVGTPEHFRRYGFPQTPADLVAHPCIAYQFGDGSLYAWELNVDGKKITHPPQGQWAFADSYMEAKAARLGLG
LAYVPEELITDDLAQGTLIRVLQRYSQRLEGSYLYYPHRNVSPALRAVIDTLRM
>Mature_293_residues
AKRENYNDLYLFMQVVREGSFTAAAQRLGLAQSGVSRAVRELEERLGVQLLVRTTRRLSLTQAGEQLYHNVESGFDALDM
GLATLAHYRQTPSGTVRINASQHAIDKVLLPKLAVFKQRYPDIRLELISESRFVDIIAQRFDAGVRLGPEVGSGMIAVRI
SPDMEMAVVGTPEHFRRYGFPQTPADLVAHPCIAYQFGDGSLYAWELNVDGKKITHPPQGQWAFADSYMEAKAARLGLGL
AYVPEELITDDLAQGTLIRVLQRYSQRLEGSYLYYPHRNVSPALRAVIDTLRM

Specific function: May have a role in the regulation of oprD expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=39.5904436860068, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=38.1443298969072, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1786401, Length=286, Percent_Identity=32.5174825174825, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=29.4117647058824, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=28.956228956229, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI145693193, Length=277, Percent_Identity=31.7689530685921, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786448, Length=281, Percent_Identity=29.5373665480427, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=23.859649122807, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788706, Length=259, Percent_Identity=27.4131274131274, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788481, Length=287, Percent_Identity=29.2682926829268, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788748, Length=126, Percent_Identity=44.4444444444444, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082132, Length=288, Percent_Identity=25, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790011, Length=277, Percent_Identity=23.826714801444, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI157672245, Length=141, Percent_Identity=31.9148936170213, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789173, Length=261, Percent_Identity=25.6704980842912, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787601, Length=139, Percent_Identity=26.6187050359712, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32956; Mature: 32825

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRENYNDLYLFMQVVREGSFTAAAQRLGLAQSGVSRAVRELEERLGVQLLVRTTRRLS
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LTQAGEQLYHNVESGFDALDMGLATLAHYRQTPSGTVRINASQHAIDKVLLPKLAVFKQR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHH
YPDIRLELISESRFVDIIAQRFDAGVRLGPEVGSGMIAVRISPDMEMAVVGTPEHFRRYG
CCCCEEEHHCCHHHHHHHHHHHCCCCEECCCCCCCEEEEEECCCCEEEEECCHHHHHHCC
FPQTPADLVAHPCIAYQFGDGSLYAWELNVDGKKITHPPQGQWAFADSYMEAKAARLGLG
CCCCCHHHHHCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHCCC
LAYVPEELITDDLAQGTLIRVLQRYSQRLEGSYLYYPHRNVSPALRAVIDTLRM
HHHCCHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AKRENYNDLYLFMQVVREGSFTAAAQRLGLAQSGVSRAVRELEERLGVQLLVRTTRRLS
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LTQAGEQLYHNVESGFDALDMGLATLAHYRQTPSGTVRINASQHAIDKVLLPKLAVFKQR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHH
YPDIRLELISESRFVDIIAQRFDAGVRLGPEVGSGMIAVRISPDMEMAVVGTPEHFRRYG
CCCCEEEHHCCHHHHHHHHHHHCCCCEECCCCCCCEEEEEECCCCEEEEECCHHHHHHCC
FPQTPADLVAHPCIAYQFGDGSLYAWELNVDGKKITHPPQGQWAFADSYMEAKAARLGLG
CCCCCHHHHHCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHCCC
LAYVPEELITDDLAQGTLIRVLQRYSQRLEGSYLYYPHRNVSPALRAVIDTLRM
HHHCCHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]