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The map label for this gene is licH [H]

Identifier: 238894367

GI number: 238894367

Start: 2258613

End: 2259971

Strand: Direct

Name: licH [H]

Synonym: KP1_2349

Alternate gene names: 238894367

Gene position: 2258613-2259971 (Clockwise)

Preceding gene: 238894365

Following gene: 238894368

Centisome position: 43.03

GC content: 57.91

Gene sequence:

>1359_bases
TTGCCGGTTTTAAATAGTTATATCGTAACTAAACCGAGGTATACCATGTCAGGACTCAAAATTGTGGTGATTGGCGGTGG
CTCCAGCTACACCCCGGAACTGATTGAAGGTTTGCTCAACCGCTATCATGAAATGCCGGTCGCTTCGCTATGGCTGGTGG
ACATTGAAGAGGGCAAAGAGAAAGTCGAGATTATCGCCGGACTGGCGCGGCGAATGATCGCCAAAGCCGGGCTGACTATT
GAAGTGGTGGCCACCCTTGACCGGGAAAGCGCGCTGCGCAATGCCGATTTCGTCTGCTCGCAGTTTCGCGCCGGCTGCCT
TGACGCCCGCATCAGCGATGAACGTATCTCCCTCAAGTATGGCTTGATCGGCCAGGAGACCAATGGCCTTGGCGGCTTCG
CCAACGCCTGTCGCACCATTCCCATCGCCCTGGAGATCGCTGCCGATATGGAGCGACTGTGTCCCGACGCCTGGCTGCTG
AACTTTACCAACCCGTCGGGGATGGTGACCGAAGCGATCCTGCGCCACAGCCGCATCAAAGCCGTCGGCCTGTGTAACGT
GCCGGTGATTATGCAAAAAGGGATAACCACTCTGCTGCAATGCGCTGACGAAAAAGAGGTGGTGATGCAGGTCGCCGGCC
TGAACCACTTTATCTTCGTGCGCCAGATCCTGCACAAAGGTAAAGAATGGCTGCCGGAGGTGATAGCCGAGATCAACGCC
GGTCGGGATCCGCTGGTGCCGCGCAACATTCCGCCGTTCCGTTGGCCGTCGCATCTGCTGCAGGGCTTAGGCATGATCCC
CTGCGCCTATCTGCGTTATTACTACATGAAAGACGATCTGCTGCGCCAGGAGCTGGCGGAGGCGGGCGGCGAAGGAACCC
GGGGGGAAGTGGTTAAGCAGCTGGAAAAAATCTTGTTTGACCAGTACCGCGACCCTCACCTGGCGGTCAAACCGAAGGCG
CTGGAAGGGCGCGGCGGCCAGTACTATTCCGAGGCGGCCTGCGAGCTGATGAATGCCATCTACAACGACAAGCGGATTAT
CATGCACGTCAATACGCGTAATAACGGCGCCATCAATGGCCTGCCGGATGACTGCGCGGTAGAGGTCAGCTCGCTGATTA
CCGCTTCTGGTCCGCTACCTCTCAATGTGGCGCCGTTCCCGGAAGATACCCTGCGTTTGCTGCAGCTGATGAAATCATTT
GAACGGCTGACTATCGAGGCCGCGCTCACCGGCAACCGCCACACCGCATGGCGTGCTCTGATGCTGAATCCGCTGATCGT
CAGCGGCGAGAAGCTCGAACTGGCGTTGGATGAGGTGATCGCTGAGAACCGTCAGTGGCTGCCTGCTTTCCACGCCTGA

Upstream 100 bases:

>100_bases
AGCAGCGCAAGGATGCTTTGTTGCTCAAGCACAGATTGTCTCCCTTATGCATTAACTGAGTTCATGCATAGGCCGATTTA
ATTCGTTTGTTAGGCCAGTT

Downstream 100 bases:

>100_bases
CCCAAGACTCACCGGCCGCCTGGCCGGTGATTTAACCACTGACCGTCTGACTTTACGCCACAGCGCCCATTTTTCCGCCA
CACTGTCAATAATTGTTGAC

Product: putative alpha-galactosidases/6-phospho-beta- glucosidases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MPVLNSYIVTKPRYTMSGLKIVVIGGGSSYTPELIEGLLNRYHEMPVASLWLVDIEEGKEKVEIIAGLARRMIAKAGLTI
EVVATLDRESALRNADFVCSQFRAGCLDARISDERISLKYGLIGQETNGLGGFANACRTIPIALEIAADMERLCPDAWLL
NFTNPSGMVTEAILRHSRIKAVGLCNVPVIMQKGITTLLQCADEKEVVMQVAGLNHFIFVRQILHKGKEWLPEVIAEINA
GRDPLVPRNIPPFRWPSHLLQGLGMIPCAYLRYYYMKDDLLRQELAEAGGEGTRGEVVKQLEKILFDQYRDPHLAVKPKA
LEGRGGQYYSEAACELMNAIYNDKRIIMHVNTRNNGAINGLPDDCAVEVSSLITASGPLPLNVAPFPEDTLRLLQLMKSF
ERLTIEAALTGNRHTAWRALMLNPLIVSGEKLELALDEVIAENRQWLPAFHA

Sequences:

>Translated_452_residues
MPVLNSYIVTKPRYTMSGLKIVVIGGGSSYTPELIEGLLNRYHEMPVASLWLVDIEEGKEKVEIIAGLARRMIAKAGLTI
EVVATLDRESALRNADFVCSQFRAGCLDARISDERISLKYGLIGQETNGLGGFANACRTIPIALEIAADMERLCPDAWLL
NFTNPSGMVTEAILRHSRIKAVGLCNVPVIMQKGITTLLQCADEKEVVMQVAGLNHFIFVRQILHKGKEWLPEVIAEINA
GRDPLVPRNIPPFRWPSHLLQGLGMIPCAYLRYYYMKDDLLRQELAEAGGEGTRGEVVKQLEKILFDQYRDPHLAVKPKA
LEGRGGQYYSEAACELMNAIYNDKRIIMHVNTRNNGAINGLPDDCAVEVSSLITASGPLPLNVAPFPEDTLRLLQLMKSF
ERLTIEAALTGNRHTAWRALMLNPLIVSGEKLELALDEVIAENRQWLPAFHA
>Mature_451_residues
PVLNSYIVTKPRYTMSGLKIVVIGGGSSYTPELIEGLLNRYHEMPVASLWLVDIEEGKEKVEIIAGLARRMIAKAGLTIE
VVATLDRESALRNADFVCSQFRAGCLDARISDERISLKYGLIGQETNGLGGFANACRTIPIALEIAADMERLCPDAWLLN
FTNPSGMVTEAILRHSRIKAVGLCNVPVIMQKGITTLLQCADEKEVVMQVAGLNHFIFVRQILHKGKEWLPEVIAEINAG
RDPLVPRNIPPFRWPSHLLQGLGMIPCAYLRYYYMKDDLLRQELAEAGGEGTRGEVVKQLEKILFDQYRDPHLAVKPKAL
EGRGGQYYSEAACELMNAIYNDKRIIMHVNTRNNGAINGLPDDCAVEVSSLITASGPLPLNVAPFPEDTLRLLQLMKSFE
RLTIEAALTGNRHTAWRALMLNPLIVSGEKLELALDEVIAENRQWLPAFHA

Specific function: Hydrolyzes phospho-beta-glucosides (Probable) [H]

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=435, Percent_Identity=44.5977011494253, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1790560, Length=468, Percent_Identity=28.6324786324786, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 50195; Mature: 50064

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS01324 GLYCOSYL_HYDROL_F4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVLNSYIVTKPRYTMSGLKIVVIGGGSSYTPELIEGLLNRYHEMPVASLWLVDIEEGKE
CCCCCCEEEECCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHCCHH
KVEIIAGLARRMIAKAGLTIEVVATLDRESALRNADFVCSQFRAGCLDARISDERISLKY
HHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEE
GLIGQETNGLGGFANACRTIPIALEIAADMERLCPDAWLLNFTNPSGMVTEAILRHSRIK
EEECCCCCCCCHHHHHHHHCCEEEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCC
AVGLCNVPVIMQKGITTLLQCADEKEVVMQVAGLNHFIFVRQILHKGKEWLPEVIAEINA
EEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCC
GRDPLVPRNIPPFRWPSHLLQGLGMIPCAYLRYYYMKDDLLRQELAEAGGEGTRGEVVKQ
CCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LEKILFDQYRDPHLAVKPKALEGRGGQYYSEAACELMNAIYNDKRIIMHVNTRNNGAING
HHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
LPDDCAVEVSSLITASGPLPLNVAPFPEDTLRLLQLMKSFERLTIEAALTGNRHTAWRAL
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHH
MLNPLIVSGEKLELALDEVIAENRQWLPAFHA
HHCCEEECCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PVLNSYIVTKPRYTMSGLKIVVIGGGSSYTPELIEGLLNRYHEMPVASLWLVDIEEGKE
CCCCCEEEECCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHCCHH
KVEIIAGLARRMIAKAGLTIEVVATLDRESALRNADFVCSQFRAGCLDARISDERISLKY
HHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEE
GLIGQETNGLGGFANACRTIPIALEIAADMERLCPDAWLLNFTNPSGMVTEAILRHSRIK
EEECCCCCCCCHHHHHHHHCCEEEEHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCC
AVGLCNVPVIMQKGITTLLQCADEKEVVMQVAGLNHFIFVRQILHKGKEWLPEVIAEINA
EEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCC
GRDPLVPRNIPPFRWPSHLLQGLGMIPCAYLRYYYMKDDLLRQELAEAGGEGTRGEVVKQ
CCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LEKILFDQYRDPHLAVKPKALEGRGGQYYSEAACELMNAIYNDKRIIMHVNTRNNGAING
HHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
LPDDCAVEVSSLITASGPLPLNVAPFPEDTLRLLQLMKSFERLTIEAALTGNRHTAWRAL
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHH
MLNPLIVSGEKLELALDEVIAENRQWLPAFHA
HHCCEEECCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 9384377; 8969509 [H]