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The map label for this gene is hipO [H]

Identifier: 238894357

GI number: 238894357

Start: 2249691

End: 2250893

Strand: Direct

Name: hipO [H]

Synonym: KP1_2339

Alternate gene names: 238894357

Gene position: 2249691-2250893 (Clockwise)

Preceding gene: 238894355

Following gene: 238894358

Centisome position: 42.86

GC content: 62.26

Gene sequence:

>1203_bases
GTGTCGTGCAAACACAACACAGGAATAACAAAAATGACACATCCGTTGCTAGAAGCATTGCAGGTTAACGAGGCGCAATT
TATCGCTCTGCGTCGTCGGTTCCACCAGCAGCCGGAGATCGGCTTTGAAGAGCACCAGACCAGCAGCGAGGTCGCCCGAC
TGCTTGGCGAGTGGGGATACGAGGTTCACCGCGGCCTGGCGGGCACCGGAGTGGTGGGCACGCTGCGCGTCGGCGAGGGG
AAAAAACGCCTTGGCCTGCGGGCGGATATGGATGCCCTGCCGATGCAGGAGCGGAGCGGTAAGCCGTGGGCAAGCCAGGT
TGAAGGGCGCTTTCACGGCTGCGGCCATGACGGGCACACCACCACGCTGCTCTACGCAGCTGAATACCTGGCGCGCACCC
GCCAGTTTACCGGCACGCTGCAGCTGATTTTCCAGCCCGCGGAAGAGTTGCTGTACGGCGGGCGGGTAATGGTCGAGGAC
GGTCTGTTTGATCAGTTCCCCTGCGACGCCATCTTCGGCCTGCACAATATGCCGGGTCAGCCGTTGGGCAAGATCGGCCT
GCGCGACGGGGCGATGATGGCCTCCTCCGATACGCTGCATATTGAAGTGAAGGGCGTTGGCGGCCACGGCGCGGTGCCGG
AGCATACGGTGGATGCCACGCTGGTGGCCTGCCATATTACCCTCGCGCTACAGTCCATTGTCTCGCGCAATATCACCCCG
TTTGAACCGGCGGTGGTGACCGTCGGCAGCATCCAGGCCGGTCATGCGCCCAATATCATTAACGATCACGTGCTGATGAA
GCTCACGGTGCGCACCCTCAATGAGCAGGTGCGTGAGACCGTGCTGCAGCGGATCCATGATATCGCCGTGGCCCAGGCGG
AGAGCTTCAATGCCACCGCCACGCTGACCCACGTCAACGGCAGTCCGGTGTTGCGTAACGATCCGGCGACGAACGCCATG
GTGCGGGAGGTGGCGACAGCGCTGTTTGGCGCAGAGCAGGTGGGCGAGGTGAAGCCGTTTATGGGCAGTGAAGATTTTGC
CTTCATGCTGGAGCAGCACCCGCATGGCAGCTATTTCACCATCGGCGCCGGCGATGAGCCGGATCGCTGCATGGTGCATA
ACCCGGGGTATGACTTCAACGACGCGCTGTTGCTGACCGGCGCGGCGCTGTGGTGCGGCCTGACGGAACGCTATCTGCGC
TAA

Upstream 100 bases:

>100_bases
TTTGTCATAACCGATATGTATGAAAAACACTCATTGATTTTTCGTCAATATAAAACAAAAAAGCGCGCCTGCAAGCTGAG
CCACCCGCATAAACTCGAAA

Downstream 100 bases:

>100_bases
TCACGAGAAACGGGAGGGCCATGCGATGAGCACTGTCACAATAAGCGACACCCCGTTTGTCGGCAACGATCGCCTGCTGG
TGGGGATTGTGTTAAGCGTT

Product: putative amino acid amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSCKHNTGITKMTHPLLEALQVNEAQFIALRRRFHQQPEIGFEEHQTSSEVARLLGEWGYEVHRGLAGTGVVGTLRVGEG
KKRLGLRADMDALPMQERSGKPWASQVEGRFHGCGHDGHTTTLLYAAEYLARTRQFTGTLQLIFQPAEELLYGGRVMVED
GLFDQFPCDAIFGLHNMPGQPLGKIGLRDGAMMASSDTLHIEVKGVGGHGAVPEHTVDATLVACHITLALQSIVSRNITP
FEPAVVTVGSIQAGHAPNIINDHVLMKLTVRTLNEQVRETVLQRIHDIAVAQAESFNATATLTHVNGSPVLRNDPATNAM
VREVATALFGAEQVGEVKPFMGSEDFAFMLEQHPHGSYFTIGAGDEPDRCMVHNPGYDFNDALLLTGAALWCGLTERYLR

Sequences:

>Translated_400_residues
MSCKHNTGITKMTHPLLEALQVNEAQFIALRRRFHQQPEIGFEEHQTSSEVARLLGEWGYEVHRGLAGTGVVGTLRVGEG
KKRLGLRADMDALPMQERSGKPWASQVEGRFHGCGHDGHTTTLLYAAEYLARTRQFTGTLQLIFQPAEELLYGGRVMVED
GLFDQFPCDAIFGLHNMPGQPLGKIGLRDGAMMASSDTLHIEVKGVGGHGAVPEHTVDATLVACHITLALQSIVSRNITP
FEPAVVTVGSIQAGHAPNIINDHVLMKLTVRTLNEQVRETVLQRIHDIAVAQAESFNATATLTHVNGSPVLRNDPATNAM
VREVATALFGAEQVGEVKPFMGSEDFAFMLEQHPHGSYFTIGAGDEPDRCMVHNPGYDFNDALLLTGAALWCGLTERYLR
>Mature_399_residues
SCKHNTGITKMTHPLLEALQVNEAQFIALRRRFHQQPEIGFEEHQTSSEVARLLGEWGYEVHRGLAGTGVVGTLRVGEGK
KRLGLRADMDALPMQERSGKPWASQVEGRFHGCGHDGHTTTLLYAAEYLARTRQFTGTLQLIFQPAEELLYGGRVMVEDG
LFDQFPCDAIFGLHNMPGQPLGKIGLRDGAMMASSDTLHIEVKGVGGHGAVPEHTVDATLVACHITLALQSIVSRNITPF
EPAVVTVGSIQAGHAPNIINDHVLMKLTVRTLNEQVRETVLQRIHDIAVAQAESFNATATLTHVNGSPVLRNDPATNAMV
REVATALFGAEQVGEVKPFMGSEDFAFMLEQHPHGSYFTIGAGDEPDRCMVHNPGYDFNDALLLTGAALWCGLTERYLR

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=381, Percent_Identity=30.1837270341207, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 43703; Mature: 43572

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCKHNTGITKMTHPLLEALQVNEAQFIALRRRFHQQPEIGFEEHQTSSEVARLLGEWGY
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHCH
EVHRGLAGTGVVGTLRVGEGKKRLGLRADMDALPMQERSGKPWASQVEGRFHGCGHDGHT
HHHCCCCCCCCEEEEEECCCCHHCCCCCCCCCCCCHHCCCCCCHHHHCCCEECCCCCCCH
TTLLYAAEYLARTRQFTGTLQLIFQPAEELLYGGRVMVEDGLFDQFPCDAIFGLHNMPGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHCCCCCCC
PLGKIGLRDGAMMASSDTLHIEVKGVGGHGAVPEHTVDATLVACHITLALQSIVSRNITP
CCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
FEPAVVTVGSIQAGHAPNIINDHVLMKLTVRTLNEQVRETVLQRIHDIAVAQAESFNATA
CCCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
TLTHVNGSPVLRNDPATNAMVREVATALFGAEQVGEVKPFMGSEDFAFMLEQHPHGSYFT
EEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCEEHEEECCCCCEEE
IGAGDEPDRCMVHNPGYDFNDALLLTGAALWCGLTERYLR
ECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SCKHNTGITKMTHPLLEALQVNEAQFIALRRRFHQQPEIGFEEHQTSSEVARLLGEWGY
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHCH
EVHRGLAGTGVVGTLRVGEGKKRLGLRADMDALPMQERSGKPWASQVEGRFHGCGHDGHT
HHHCCCCCCCCEEEEEECCCCHHCCCCCCCCCCCCHHCCCCCCHHHHCCCEECCCCCCCH
TTLLYAAEYLARTRQFTGTLQLIFQPAEELLYGGRVMVEDGLFDQFPCDAIFGLHNMPGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHCCCCCCC
PLGKIGLRDGAMMASSDTLHIEVKGVGGHGAVPEHTVDATLVACHITLALQSIVSRNITP
CCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
FEPAVVTVGSIQAGHAPNIINDHVLMKLTVRTLNEQVRETVLQRIHDIAVAQAESFNATA
CCCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
TLTHVNGSPVLRNDPATNAMVREVATALFGAEQVGEVKPFMGSEDFAFMLEQHPHGSYFT
EEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCEEHEEECCCCCEEE
IGAGDEPDRCMVHNPGYDFNDALLLTGAALWCGLTERYLR
ECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]