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The map label for this gene is sohB [H]

Identifier: 238894328

GI number: 238894328

Start: 2217839

End: 2218885

Strand: Direct

Name: sohB [H]

Synonym: KP1_2307

Alternate gene names: 238894328

Gene position: 2217839-2218885 (Clockwise)

Preceding gene: 238894327

Following gene: 238894330

Centisome position: 42.26

GC content: 59.03

Gene sequence:

>1047_bases
GTGGAATTACTTGCTCAGTACGGCTTATTTTTAGCCAAGATCGCGACGGTTGTCGTCGCCATCGCGGTGATTGCCGCTAT
TATCGTCAACCTCGCTCAGCGCAAGAAGCAGCGCGGCGAGCTGCGGGTGACCAATCTTAGCGAGCATTATAAAGAGATGA
AGGAATCGCTGGCGGTGGCGCTGCTGGATGGCCCGCAGCAGAAGCAGTGGCATAAGGCGCAGAAGAAAAAGCAAAAACAA
GAGGCGAAGGCGGCCAAAGCGCGGGCGAAGCTGGGTAATGCCGAGCCGGAAGGCAAGCCGCGTGCCTGGGTGCTGGATTT
CAAAGGCAGTATGGATGCCCATGAGGTCAATAGCCTGCGGGAAGAGATCACCGCGGTACTGGCGGCGGCGAAAGCGCGCG
ATCAGGTGGTGATTCGCCTGGAAAGCCCCGGCGGGGTGGTGCACGGCTACGGTCTGGCCGCCTCTCAGCTGCAGCGCTTG
CGCGACAAGCAGATCCCGCTGACGGTGGCGGTCGACAAAGTGGCGGCCAGCGGCGGCTATATGATGGCCTGCGTGGCGAA
CAAAATTGTCTCGGCGCCGTTTGCGATCCTTGGCTCTATTGGCGTGGTGGCGCAGATCCCGAACCTGCACCGCTTCCTGA
AGAATAAAGATATCGATATCGAACTGCACACCGCCGGGCAGTACAAACGAACGCTCACCATGCTGGGCGAAAATACCGAG
GAAGGGCGGCGCAAGTTCCGCGAGGATCTCAATGAGACACATCATTTGTTTAAGGATTTCGTCCACCGGATGCGTCCGGG
ACTTGATATTGAGCAGGTGGCCACCGGCGAACACTGGTACGGGGTGCAGGCGCTGGAAAAAGGTCTGGTGGATGCGGTTG
AAACCAGCGATGAGCTGCTGCTGGGGCTGATTGAGAGCCACGAGGTGATCGGGGTGCGTTATCAACAGCGTAAGAAGATG
CTCGACCGCTTTACCGGTAGCGCGGCGGAGAGCGCCGATCGGCTTCTGCTGCGCTGGTGGCAGCGCGGTCAAAAACCGCT
GATGTAA

Upstream 100 bases:

>100_bases
AACGGAATCCGCTGCGCAGAGAACACAAAGCACAAAGACTTCTCGCCAGCGGCTGAGGTACACTGTGCAGCAACGTCAGT
GCTTTACACAAGGTGAAAAC

Downstream 100 bases:

>100_bases
ATAACATAACGCGAGGCCTGGGCCTCGCGTTATTGTTTTCACCGGTCTTAATCGACCAGGTGGTACTTGTCCGACAGCTC
GTGAGCAAGATACTTAAACA

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MELLAQYGLFLAKIATVVVAIAVIAAIIVNLAQRKKQRGELRVTNLSEHYKEMKESLAVALLDGPQQKQWHKAQKKKQKQ
EAKAAKARAKLGNAEPEGKPRAWVLDFKGSMDAHEVNSLREEITAVLAAAKARDQVVIRLESPGGVVHGYGLAASQLQRL
RDKQIPLTVAVDKVAASGGYMMACVANKIVSAPFAILGSIGVVAQIPNLHRFLKNKDIDIELHTAGQYKRTLTMLGENTE
EGRRKFREDLNETHHLFKDFVHRMRPGLDIEQVATGEHWYGVQALEKGLVDAVETSDELLLGLIESHEVIGVRYQQRKKM
LDRFTGSAAESADRLLLRWWQRGQKPLM

Sequences:

>Translated_348_residues
MELLAQYGLFLAKIATVVVAIAVIAAIIVNLAQRKKQRGELRVTNLSEHYKEMKESLAVALLDGPQQKQWHKAQKKKQKQ
EAKAAKARAKLGNAEPEGKPRAWVLDFKGSMDAHEVNSLREEITAVLAAAKARDQVVIRLESPGGVVHGYGLAASQLQRL
RDKQIPLTVAVDKVAASGGYMMACVANKIVSAPFAILGSIGVVAQIPNLHRFLKNKDIDIELHTAGQYKRTLTMLGENTE
EGRRKFREDLNETHHLFKDFVHRMRPGLDIEQVATGEHWYGVQALEKGLVDAVETSDELLLGLIESHEVIGVRYQQRKKM
LDRFTGSAAESADRLLLRWWQRGQKPLM
>Mature_348_residues
MELLAQYGLFLAKIATVVVAIAVIAAIIVNLAQRKKQRGELRVTNLSEHYKEMKESLAVALLDGPQQKQWHKAQKKKQKQ
EAKAAKARAKLGNAEPEGKPRAWVLDFKGSMDAHEVNSLREEITAVLAAAKARDQVVIRLESPGGVVHGYGLAASQLQRL
RDKQIPLTVAVDKVAASGGYMMACVANKIVSAPFAILGSIGVVAQIPNLHRFLKNKDIDIELHTAGQYKRTLTMLGENTE
EGRRKFREDLNETHHLFKDFVHRMRPGLDIEQVATGEHWYGVQALEKGLVDAVETSDELLLGLIESHEVIGVRYQQRKKM
LDRFTGSAAESADRLLLRWWQRGQKPLM

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=349, Percent_Identity=82.8080229226361, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI1788064, Length=177, Percent_Identity=27.683615819209, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 38845; Mature: 38845

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLAQYGLFLAKIATVVVAIAVIAAIIVNLAQRKKQRGELRVTNLSEHYKEMKESLAVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHH
LLDGPQQKQWHKAQKKKQKQEAKAAKARAKLGNAEPEGKPRAWVLDFKGSMDAHEVNSLR
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHH
EEITAVLAAAKARDQVVIRLESPGGVVHGYGLAASQLQRLRDKQIPLTVAVDKVAASGGY
HHHHHHHHHHHCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCCEEEEHHHHHCCCCC
MMACVANKIVSAPFAILGSIGVVAQIPNLHRFLKNKDIDIELHTAGQYKRTLTMLGENTE
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCCH
EGRRKFREDLNETHHLFKDFVHRMRPGLDIEQVATGEHWYGVQALEKGLVDAVETSDELL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHH
LGLIESHEVIGVRYQQRKKMLDRFTGSAAESADRLLLRWWQRGQKPLM
HHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MELLAQYGLFLAKIATVVVAIAVIAAIIVNLAQRKKQRGELRVTNLSEHYKEMKESLAVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHH
LLDGPQQKQWHKAQKKKQKQEAKAAKARAKLGNAEPEGKPRAWVLDFKGSMDAHEVNSLR
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHH
EEITAVLAAAKARDQVVIRLESPGGVVHGYGLAASQLQRLRDKQIPLTVAVDKVAASGGY
HHHHHHHHHHHCCCEEEEEECCCCCEEEECCHHHHHHHHHHHCCCCEEEEHHHHHCCCCC
MMACVANKIVSAPFAILGSIGVVAQIPNLHRFLKNKDIDIELHTAGQYKRTLTMLGENTE
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCCH
EGRRKFREDLNETHHLFKDFVHRMRPGLDIEQVATGEHWYGVQALEKGLVDAVETSDELL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHH
LGLIESHEVIGVRYQQRKKMLDRFTGSAAESADRLLLRWWQRGQKPLM
HHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]