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The map label for this gene is ttuD [H]

Identifier: 238894314

GI number: 238894314

Start: 2203257

End: 2204516

Strand: Direct

Name: ttuD [H]

Synonym: KP1_2293

Alternate gene names: 238894314

Gene position: 2203257-2204516 (Clockwise)

Preceding gene: 238894313

Following gene: 238894320

Centisome position: 41.98

GC content: 59.52

Gene sequence:

>1260_bases
ATGAATAACGAACAGGCTGCAGAGATCCTGCAGGATATCTTTCAACATGCGGTCAACAGTGCCCGCGCCGGGCCGGTGAC
CCTGGCTAACCTGCCGGAAAAACCTCGCGGCCGTTGTGTGGTGATCGGTGCGGGTAAAGCGTCCGCGGCAATGGCGGCTG
CCGTGGATGCGGCCTGGCCGGATGTGGCGGTGTCGGGCGTGGTGGTGACGCGTTACGGTTACGCGGTTCCTGCGGGCCGC
ATCCGCATTATTGAGGCGGCTCATCCCGTATCAGATGCCATGAGCGAGGTTGCCGCAATGCTGATTGTGGAGACGCTGCG
CGGTTTAACTGCCGATGATCTGGTGCTGGCATTGATTTCAGGGGGAGGGTCGGCGCTGATGGCGCTGCCCGCCCCGGGGT
TAACGCTGGCAGATAAGCAGACCATCACCCGGGCCCTGCTCCATAGCGGGGCCAGCATCAAAGAGATGAATCTGGTACGT
CGTCATCTCTCAGCGGTGAAAGGCGGAAAGCTGGCGACCATGGCGCAACCGGCGCGCATCGTATCACTGATTATCAGCGA
TGTGCCTGGCGATAATCCGACGGACGTAGCGTCTGGCCCCACCGTTGCCGATAACAGCGCACCACGTGATGCGCTCCGGG
TACTGCAGCGGTATGGCATTGCGATCCCGAAGCCCGTTAGCGAACGGCTAAACCAGCCGGCCGGCCCGGTGGAAAACGCC
GCGACAGGCGAGGTCAGGCTTATCGCCACGCCGGCGATGGCGTTAGCGGCGGCGGCTCTGGCCGCACGACAACATGGGTT
CACCCCCCTTATTTTGGGGGATGCTATAGAAGGTGAAAGCAGGGAAGTGGCGGTGGTCATGGCCGGTATGGCGAAATCGG
CGAAGCAGTATGGTCACCCGATTTCAGGGCCTGCTGTGCTGTTGTCAGGTGGCGAAACCACGGTGACAGTAAACAACACT
CAGCCTGGAAAAGGGGGCCGCAATACCGAGTTTTTACTCAGTCTGGCCTGTGCGCTCCAGGGGGAACACGGTATCTGGGC
CATGGCGGGAGATAGCGATGGTATTGATGGCACAGAAGATGCCGCAGGTGCGATCGTCTTCCCGGATACGCTTGCGCGCG
GCAAGCTGAGCGGTCTTAATGCAGTGCAATATCTGGATGGCCATGATAGTTACTGCTATTTTCACGCGCTTAATGATTTG
CTGATCACCGGCCCGACGTTAACCAACGTCAATGATATTCGGGCAATATTGATTGCCTGA

Upstream 100 bases:

>100_bases
TGACGCCAGATGTCGGTGGCTCAGCCAATACCGCGGAGGTGACACGCGCCGTGGTGCACTACATTGACGCTAAAGCTGAC
ATTGCCGAGACCGCATAACC

Downstream 100 bases:

>100_bases
CTGTATCGCTCTCCTGTGCCAGGGAGCGATATTTTTCCCTTTCAACATAGTTCAAATCTTCGGTATCCGCCCGCCATCCA
TTTCCACGCTAAAGCGCATC

Product: putative hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNNEQAAEILQDIFQHAVNSARAGPVTLANLPEKPRGRCVVIGAGKASAAMAAAVDAAWPDVAVSGVVVTRYGYAVPAGR
IRIIEAAHPVSDAMSEVAAMLIVETLRGLTADDLVLALISGGGSALMALPAPGLTLADKQTITRALLHSGASIKEMNLVR
RHLSAVKGGKLATMAQPARIVSLIISDVPGDNPTDVASGPTVADNSAPRDALRVLQRYGIAIPKPVSERLNQPAGPVENA
ATGEVRLIATPAMALAAAALAARQHGFTPLILGDAIEGESREVAVVMAGMAKSAKQYGHPISGPAVLLSGGETTVTVNNT
QPGKGGRNTEFLLSLACALQGEHGIWAMAGDSDGIDGTEDAAGAIVFPDTLARGKLSGLNAVQYLDGHDSYCYFHALNDL
LITGPTLTNVNDIRAILIA

Sequences:

>Translated_419_residues
MNNEQAAEILQDIFQHAVNSARAGPVTLANLPEKPRGRCVVIGAGKASAAMAAAVDAAWPDVAVSGVVVTRYGYAVPAGR
IRIIEAAHPVSDAMSEVAAMLIVETLRGLTADDLVLALISGGGSALMALPAPGLTLADKQTITRALLHSGASIKEMNLVR
RHLSAVKGGKLATMAQPARIVSLIISDVPGDNPTDVASGPTVADNSAPRDALRVLQRYGIAIPKPVSERLNQPAGPVENA
ATGEVRLIATPAMALAAAALAARQHGFTPLILGDAIEGESREVAVVMAGMAKSAKQYGHPISGPAVLLSGGETTVTVNNT
QPGKGGRNTEFLLSLACALQGEHGIWAMAGDSDGIDGTEDAAGAIVFPDTLARGKLSGLNAVQYLDGHDSYCYFHALNDL
LITGPTLTNVNDIRAILIA
>Mature_419_residues
MNNEQAAEILQDIFQHAVNSARAGPVTLANLPEKPRGRCVVIGAGKASAAMAAAVDAAWPDVAVSGVVVTRYGYAVPAGR
IRIIEAAHPVSDAMSEVAAMLIVETLRGLTADDLVLALISGGGSALMALPAPGLTLADKQTITRALLHSGASIKEMNLVR
RHLSAVKGGKLATMAQPARIVSLIISDVPGDNPTDVASGPTVADNSAPRDALRVLQRYGIAIPKPVSERLNQPAGPVENA
ATGEVRLIATPAMALAAAALAARQHGFTPLILGDAIEGESREVAVVMAGMAKSAKQYGHPISGPAVLLSGGETTVTVNNT
QPGKGGRNTEFLLSLACALQGEHGIWAMAGDSDGIDGTEDAAGAIVFPDTLARGKLSGLNAVQYLDGHDSYCYFHALNDL
LITGPTLTNVNDIRAILIA

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=491, Percent_Identity=33.8085539714868, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI193205461, Length=412, Percent_Identity=32.2815533980583, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI19920578, Length=432, Percent_Identity=29.8611111111111, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 43075; Mature: 43075

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNEQAAEILQDIFQHAVNSARAGPVTLANLPEKPRGRCVVIGAGKASAAMAAAVDAAWP
CCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCCC
DVAVSGVVVTRYGYAVPAGRIRIIEAAHPVSDAMSEVAAMLIVETLRGLTADDLVLALIS
CHHHCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEC
GGGSALMALPAPGLTLADKQTITRALLHSGASIKEMNLVRRHLSAVKGGKLATMAQPARI
CCCCEEEEECCCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHH
VSLIISDVPGDNPTDVASGPTVADNSAPRDALRVLQRYGIAIPKPVSERLNQPAGPVENA
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCC
ATGEVRLIATPAMALAAAALAARQHGFTPLILGDAIEGESREVAVVMAGMAKSAKQYGHP
CCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEHHHHHHHHHHCCC
ISGPAVLLSGGETTVTVNNTQPGKGGRNTEFLLSLACALQGEHGIWAMAGDSDGIDGTED
CCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
AAGAIVFPDTLARGKLSGLNAVQYLDGHDSYCYFHALNDLLITGPTLTNVNDIRAILIA
CCCEEECCCHHCCCCCCCCCCEEEECCCCCEEEEEECCCCEEECCCCCCCCCCEEEEEC
>Mature Secondary Structure
MNNEQAAEILQDIFQHAVNSARAGPVTLANLPEKPRGRCVVIGAGKASAAMAAAVDAAWP
CCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCCC
DVAVSGVVVTRYGYAVPAGRIRIIEAAHPVSDAMSEVAAMLIVETLRGLTADDLVLALIS
CHHHCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEC
GGGSALMALPAPGLTLADKQTITRALLHSGASIKEMNLVRRHLSAVKGGKLATMAQPARI
CCCCEEEEECCCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHH
VSLIISDVPGDNPTDVASGPTVADNSAPRDALRVLQRYGIAIPKPVSERLNQPAGPVENA
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCC
ATGEVRLIATPAMALAAAALAARQHGFTPLILGDAIEGESREVAVVMAGMAKSAKQYGHP
CCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEHHHHHHHHHHCCC
ISGPAVLLSGGETTVTVNNTQPGKGGRNTEFLLSLACALQGEHGIWAMAGDSDGIDGTED
CCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
AAGAIVFPDTLARGKLSGLNAVQYLDGHDSYCYFHALNDLLITGPTLTNVNDIRAILIA
CCCEEECCCHHCCCCCCCCCCEEEECCCCCEEEEEECCCCEEECCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]