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The map label for this gene is ttuA [H]

Identifier: 238894311

GI number: 238894311

Start: 2199804

End: 2200712

Strand: Reverse

Name: ttuA [H]

Synonym: KP1_2290

Alternate gene names: 238894311

Gene position: 2200712-2199804 (Counterclockwise)

Preceding gene: 238894315

Following gene: 238894309

Centisome position: 41.93

GC content: 51.05

Gene sequence:

>909_bases
ATGGATATAAATCAGCTACGTTGCTTTGTGGTGTTAGGTGATGAGCTTCACTTTGGCCGGGCTGCCCGTAAACTCGAAAT
GATGCCTGCGTCACTGAGTCGCTTTATTAAGCTACTGGAAGATGATTTGGGGATCAGGCTACTGAATCGATCGACCCGCA
ACGTGTCGCTAACACCTGAAGGCGCCGCCTTTTTAAATGAGGCCAAAACGGTCATTGCTGATTTCGATGCGCTACGGCAG
CGATTCCGGAAAAATAGCCTGTTGCAGAAAAGAACGTTGCGGATCGGGGCTATCGACAGCGCAGCCAAAGGATTACTTCC
TGAATTGCTTAATCTTTTTGTCAGGCGTTTTCCTGAAGCAGATATTCATCTTACAGAAGATAAATCTCACAAACTTATCC
CCCGACTCATTTCAGGGTGGCTGGATGTGGTTTTTGTGCGCCCGCCGGAACATATTGATGCCACGCTGACAGCGCGTTTT
ATCGCCAATGAAACCTGCGTGCTCGCCGTGCCCGCTCATCACCGGCTGGTCAGTTATGACGAAGTCAGTATCGATGATTT
CCGACACGAGCCGGTTATCTTGCCGGAAAGACGCACCCGGCGTCACAGCCATGACCTGACAATGAATATTTTCAAAGAGG
GGGGCAGCATGCCTGTCATCGCGCAGTATGCTGAAGAGAAGCAGACTATCCTGAGTTTTGTTGCCGCAGGACTCGGCATT
GCTCTGGTGCCAGCGTCCTATAAAGACATGAATGCCGACGGCGTGAAATACCTTGCGCTCACGCCGAAAAAGCATGTCGA
AGGGCTCCCCCTCAGCGCGATGTGGCATCAGGGAAACAACACTCTCTATGTGAGATCCCTGCTGGAGATACTTTCCGACA
ACATCGACGAACTGACCCGTGAGTTGTGA

Upstream 100 bases:

>100_bases
TGTTATCGTTTTGTAATAATCCCAGTATGAAGTTTTGAACCGCTTTATCATCGGCACGGCTTTATATAAATAATTTGTAT
AATCAGGTTTTGGTGAAAAG

Downstream 100 bases:

>100_bases
CGCAAAAGCTGATTGTTGCGCCAGGCGGCAACACACGAGAATTTAGCCTGGTTGCTGCAAACTGTCGGCGTATTTGCGCG
TTAAGCGAAACAGCGCCTGC

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: Tartrate utilization transcriptional regulator [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MDINQLRCFVVLGDELHFGRAARKLEMMPASLSRFIKLLEDDLGIRLLNRSTRNVSLTPEGAAFLNEAKTVIADFDALRQ
RFRKNSLLQKRTLRIGAIDSAAKGLLPELLNLFVRRFPEADIHLTEDKSHKLIPRLISGWLDVVFVRPPEHIDATLTARF
IANETCVLAVPAHHRLVSYDEVSIDDFRHEPVILPERRTRRHSHDLTMNIFKEGGSMPVIAQYAEEKQTILSFVAAGLGI
ALVPASYKDMNADGVKYLALTPKKHVEGLPLSAMWHQGNNTLYVRSLLEILSDNIDELTREL

Sequences:

>Translated_302_residues
MDINQLRCFVVLGDELHFGRAARKLEMMPASLSRFIKLLEDDLGIRLLNRSTRNVSLTPEGAAFLNEAKTVIADFDALRQ
RFRKNSLLQKRTLRIGAIDSAAKGLLPELLNLFVRRFPEADIHLTEDKSHKLIPRLISGWLDVVFVRPPEHIDATLTARF
IANETCVLAVPAHHRLVSYDEVSIDDFRHEPVILPERRTRRHSHDLTMNIFKEGGSMPVIAQYAEEKQTILSFVAAGLGI
ALVPASYKDMNADGVKYLALTPKKHVEGLPLSAMWHQGNNTLYVRSLLEILSDNIDELTREL
>Mature_302_residues
MDINQLRCFVVLGDELHFGRAARKLEMMPASLSRFIKLLEDDLGIRLLNRSTRNVSLTPEGAAFLNEAKTVIADFDALRQ
RFRKNSLLQKRTLRIGAIDSAAKGLLPELLNLFVRRFPEADIHLTEDKSHKLIPRLISGWLDVVFVRPPEHIDATLTARF
IANETCVLAVPAHHRLVSYDEVSIDDFRHEPVILPERRTRRHSHDLTMNIFKEGGSMPVIAQYAEEKQTILSFVAAGLGI
ALVPASYKDMNADGVKYLALTPKKHVEGLPLSAMWHQGNNTLYVRSLLEILSDNIDELTREL

Specific function: Transcriptional regulator of the ttuABCDE tartrate utilization operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=276, Percent_Identity=29.3478260869565, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI2367136, Length=257, Percent_Identity=28.7937743190661, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788887, Length=299, Percent_Identity=27.0903010033445, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790399, Length=295, Percent_Identity=28.135593220339, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790208, Length=273, Percent_Identity=27.1062271062271, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787806, Length=283, Percent_Identity=25.7950530035336, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787530, Length=256, Percent_Identity=23.4375, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787589, Length=129, Percent_Identity=37.2093023255814, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI157672245, Length=256, Percent_Identity=25.390625, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786401, Length=305, Percent_Identity=25.9016393442623, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=24.9158249158249, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693193, Length=285, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693105, Length=247, Percent_Identity=24.2914979757085, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788748, Length=244, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081904, Length=220, Percent_Identity=25.4545454545455, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787601, Length=176, Percent_Identity=23.8636363636364, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787128, Length=129, Percent_Identity=31.0077519379845, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1786448, Length=128, Percent_Identity=32.8125, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34161; Mature: 34161

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINQLRCFVVLGDELHFGRAARKLEMMPASLSRFIKLLEDDLGIRLLNRSTRNVSLTPE
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCC
GAAFLNEAKTVIADFDALRQRFRKNSLLQKRTLRIGAIDSAAKGLLPELLNLFVRRFPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCC
DIHLTEDKSHKLIPRLISGWLDVVFVRPPEHIDATLTARFIANETCVLAVPAHHRLVSYD
CEEEECCCCCHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCEEECC
EVSIDDFRHEPVILPERRTRRHSHDLTMNIFKEGGSMPVIAQYAEEKQTILSFVAAGLGI
CCCHHHCCCCCEECCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCE
ALVPASYKDMNADGVKYLALTPKKHVEGLPLSAMWHQGNNTLYVRSLLEILSDNIDELTR
EEECCCCCCCCCCCEEEEEECCHHHCCCCCCHHEEECCCCEEHHHHHHHHHHCCHHHHHH
EL
CC
>Mature Secondary Structure
MDINQLRCFVVLGDELHFGRAARKLEMMPASLSRFIKLLEDDLGIRLLNRSTRNVSLTPE
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCC
GAAFLNEAKTVIADFDALRQRFRKNSLLQKRTLRIGAIDSAAKGLLPELLNLFVRRFPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCC
DIHLTEDKSHKLIPRLISGWLDVVFVRPPEHIDATLTARFIANETCVLAVPAHHRLVSYD
CEEEECCCCCHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCEEECC
EVSIDDFRHEPVILPERRTRRHSHDLTMNIFKEGGSMPVIAQYAEEKQTILSFVAAGLGI
CCCHHHCCCCCEECCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCE
ALVPASYKDMNADGVKYLALTPKKHVEGLPLSAMWHQGNNTLYVRSLLEILSDNIDELTR
EEECCCCCCCCCCCEEEEEECCHHHCCCCCCHHEEECCCCEEHHHHHHHHHHCCHHHHHH
EL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]