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The map label for this gene is argD [H]

Identifier: 238894276

GI number: 238894276

Start: 2165804

End: 2167024

Strand: Direct

Name: argD [H]

Synonym: KP1_2251

Alternate gene names: 238894276

Gene position: 2165804-2167024 (Clockwise)

Preceding gene: 238894267

Following gene: 238894277

Centisome position: 41.27

GC content: 63.06

Gene sequence:

>1221_bases
ATGTCTCAGTCAATTACGCGTAACCACTTTGATGAATGGATGATGCCGGTCTACGCGCCAGCGGCGTTTATTCCGGTGCG
GGGCGCCGGGTCACGGCTGTGGGATCAGCAGGGCAAAGAGTATATCGATTTTGCCGGCGGCATCGCCGTGAACGCGCTGG
GGCATGCCCATCCGCGTCTGGTGCAAGCCCTGACCGACCAGGCCGGCAAGTTCTGGCATACCGGCAACGGCTACACCAAT
GAGCCGATCCTGCGTCTGGCCAAAATGCTTATCGATGCTACCTTCGCCGACCGGGTCTTCTTCTGTAATTCCGGCGCCGA
GGCCAATGAGGCAGCGCTCAAGCTGGCGCGTAAATATGCCCACGATCGCTTTGGCAGCGAGAAAAGTGGCATCGTCGCCT
TTCAGAACGCTTTCCACGGGCGGACGCTGTTCACCGTCTCGGCGGGCGGTCAGCCGGCCTATTCCCGGGATTTCGCCCCG
CTGCCGCCGCAGATCCAGCATGCCGTATTTAACGATCTCGAGTCGGCAAAGGCCTTAATCAATGACCAGACCTGCGCGGT
GATCGTCGAGCCGGTGCAGGGCGAAGGGGGCGTGGTGCCGGCCAGCGTCGAGTTTTTACGCGGCCTGCGTCAGCTTTGCG
ACCAGCACAACGCCCTGCTGATTTTCGATGAAGTGCAGACCGGGGTCGGGCGCACCGGCGAGCTGTATGCCTATATGCAC
TACGGCGTGACGCCCGATGTGCTGACCACCGCCAAAGCGCTGGGCGGTGGTTTCCCCATTGGCGCGCTGCTGGCGACAGA
GGCCTGCGCCAGCGTGATGACCGTCGGCACCCACGGCACCACCTACGGCGGTAACCCGCTGGCCGGGGCGGTGGCCGGCG
AACTGCTGTCGATCGTCAACACCCCGGAAGTGCTCTCCGGCGTCAGACAGCGCCACCAGTGGTTTTGTGAACGCCTGCAG
GCAATTAACGCCCGCTATGGCCTGTTCAAGGAGATCCGCGGCCTGGGACTGCTGCTCGGCTGCGTGCTAAACGACGCCTG
GGCCGGGAAGGCGAAAACCCTCAGTAACCTGGCGGCGGAAGAGGGGGTGATGATTCTGATCGCCGGCGCCAACGTGGTGC
GTTTCGCGCCGGCGCTGAACGTCAGTGAAGAAGAGGTGAACAGCGGGCTGGATCGCGTCGAGCGGGCCTGCGCGCGTTTC
GTGGCAGGAGTCTCATCATGA

Upstream 100 bases:

>100_bases
TTATCGCTGGCTGGCACGAACCGTGCAATCTACATTTACAGCGTGATAACTCATATTTATTAACATTATTGCTACTTTTA
ATTTACCGGAAGAGGTCGAT

Downstream 100 bases:

>100_bases
TGGTTATTCGACCAGTGGAGCCGGGCGATTTGCCCGGGCTGCTGAAGCTGGCAGCGGAGACCGGCGGCGGGCTGACCTCG
CTGCCGGTGGATGAAGCGAC

Product: bifunctional succinylornithine transaminase/acetylornithine transaminase

Products: NA

Alternate protein names: Succinylornithine aminotransferase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSQSITRNHFDEWMMPVYAPAAFIPVRGAGSRLWDQQGKEYIDFAGGIAVNALGHAHPRLVQALTDQAGKFWHTGNGYTN
EPILRLAKMLIDATFADRVFFCNSGAEANEAALKLARKYAHDRFGSEKSGIVAFQNAFHGRTLFTVSAGGQPAYSRDFAP
LPPQIQHAVFNDLESAKALINDQTCAVIVEPVQGEGGVVPASVEFLRGLRQLCDQHNALLIFDEVQTGVGRTGELYAYMH
YGVTPDVLTTAKALGGGFPIGALLATEACASVMTVGTHGTTYGGNPLAGAVAGELLSIVNTPEVLSGVRQRHQWFCERLQ
AINARYGLFKEIRGLGLLLGCVLNDAWAGKAKTLSNLAAEEGVMILIAGANVVRFAPALNVSEEEVNSGLDRVERACARF
VAGVSS

Sequences:

>Translated_406_residues
MSQSITRNHFDEWMMPVYAPAAFIPVRGAGSRLWDQQGKEYIDFAGGIAVNALGHAHPRLVQALTDQAGKFWHTGNGYTN
EPILRLAKMLIDATFADRVFFCNSGAEANEAALKLARKYAHDRFGSEKSGIVAFQNAFHGRTLFTVSAGGQPAYSRDFAP
LPPQIQHAVFNDLESAKALINDQTCAVIVEPVQGEGGVVPASVEFLRGLRQLCDQHNALLIFDEVQTGVGRTGELYAYMH
YGVTPDVLTTAKALGGGFPIGALLATEACASVMTVGTHGTTYGGNPLAGAVAGELLSIVNTPEVLSGVRQRHQWFCERLQ
AINARYGLFKEIRGLGLLLGCVLNDAWAGKAKTLSNLAAEEGVMILIAGANVVRFAPALNVSEEEVNSGLDRVERACARF
VAGVSS
>Mature_405_residues
SQSITRNHFDEWMMPVYAPAAFIPVRGAGSRLWDQQGKEYIDFAGGIAVNALGHAHPRLVQALTDQAGKFWHTGNGYTNE
PILRLAKMLIDATFADRVFFCNSGAEANEAALKLARKYAHDRFGSEKSGIVAFQNAFHGRTLFTVSAGGQPAYSRDFAPL
PPQIQHAVFNDLESAKALINDQTCAVIVEPVQGEGGVVPASVEFLRGLRQLCDQHNALLIFDEVQTGVGRTGELYAYMHY
GVTPDVLTTAKALGGGFPIGALLATEACASVMTVGTHGTTYGGNPLAGAVAGELLSIVNTPEVLSGVRQRHQWFCERLQA
INARYGLFKEIRGLGLLLGCVLNDAWAGKAKTLSNLAAEEGVMILIAGANVVRFAPALNVSEEEVNSGLDRVERACARFV
AGVSS

Specific function: Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=31.5245478036176, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=32.4503311258278, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI13994255, Length=410, Percent_Identity=25.609756097561, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI37574042, Length=409, Percent_Identity=25.6723716381418, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI226442709, Length=382, Percent_Identity=25.6544502617801, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI226442705, Length=409, Percent_Identity=24.9388753056235, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI24119277, Length=395, Percent_Identity=25.3164556962025, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI188536080, Length=410, Percent_Identity=24.6341463414634, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI38679950, Length=410, Percent_Identity=24.6341463414634, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI38679946, Length=410, Percent_Identity=24.6341463414634, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1788044, Length=406, Percent_Identity=80.5418719211823, Blast_Score=689, Evalue=0.0,
Organism=Escherichia coli, GI1789759, Length=398, Percent_Identity=60.0502512562814, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI145693181, Length=388, Percent_Identity=36.340206185567, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=33.2493702770781, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1787560, Length=393, Percent_Identity=33.3333333333333, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1786349, Length=401, Percent_Identity=30.4239401496259, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786991, Length=296, Percent_Identity=31.7567567567568, Blast_Score=118, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=390, Percent_Identity=32.8205128205128, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI32564660, Length=435, Percent_Identity=28.0459770114943, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=288, Percent_Identity=32.6388888888889, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=28.0092592592593, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71981843, Length=164, Percent_Identity=30.4878048780488, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17541228, Length=429, Percent_Identity=23.3100233100233, Blast_Score=92, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=41.3265306122449, Blast_Score=292, Evalue=7e-80,
Organism=Saccharomyces cerevisiae, GI6323470, Length=400, Percent_Identity=33.75, Blast_Score=219, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=301, Percent_Identity=29.9003322259136, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=429, Percent_Identity=23.7762237762238, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=32.4675324675325, Blast_Score=208, Evalue=6e-54,
Organism=Drosophila melanogaster, GI161085790, Length=448, Percent_Identity=28.5714285714286, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI28574759, Length=443, Percent_Identity=27.9909706546275, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21356575, Length=354, Percent_Identity=27.1186440677966, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI281366494, Length=435, Percent_Identity=24.1379310344828, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24667139, Length=435, Percent_Identity=24.1379310344828, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24667143, Length=435, Percent_Identity=24.1379310344828, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.81 [H]

Molecular weight: Translated: 43491; Mature: 43360

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSITRNHFDEWMMPVYAPAAFIPVRGAGSRLWDQQGKEYIDFAGGIAVNALGHAHPRL
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCHHHHHCCCHHHHHHCCCHHHH
VQALTDQAGKFWHTGNGYTNEPILRLAKMLIDATFADRVFFCNSGAEANEAALKLARKYA
HHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHH
HDRFGSEKSGIVAFQNAFHGRTLFTVSAGGQPAYSRDFAPLPPQIQHAVFNDLESAKALI
HHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NDQTCAVIVEPVQGEGGVVPASVEFLRGLRQLCDQHNALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEEEE
YGVTPDVLTTAKALGGGFPIGALLATEACASVMTVGTHGTTYGGNPLAGAVAGELLSIVN
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHC
TPEVLSGVRQRHQWFCERLQAINARYGLFKEIRGLGLLLGCVLNDAWAGKAKTLSNLAAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
EGVMILIAGANVVRFAPALNVSEEEVNSGLDRVERACARFVAGVSS
CCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQSITRNHFDEWMMPVYAPAAFIPVRGAGSRLWDQQGKEYIDFAGGIAVNALGHAHPRL
CCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCHHHHHCCCHHHHHHCCCHHHH
VQALTDQAGKFWHTGNGYTNEPILRLAKMLIDATFADRVFFCNSGAEANEAALKLARKYA
HHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHH
HDRFGSEKSGIVAFQNAFHGRTLFTVSAGGQPAYSRDFAPLPPQIQHAVFNDLESAKALI
HHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NDQTCAVIVEPVQGEGGVVPASVEFLRGLRQLCDQHNALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEEEE
YGVTPDVLTTAKALGGGFPIGALLATEACASVMTVGTHGTTYGGNPLAGAVAGELLSIVN
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHC
TPEVLSGVRQRHQWFCERLQAINARYGLFKEIRGLGLLLGCVLNDAWAGKAKTLSNLAAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
EGVMILIAGANVVRFAPALNVSEEEVNSGLDRVERACARFVAGVSS
CCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA