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The map label for this gene is qorA [H]

Identifier: 238894264

GI number: 238894264

Start: 2153991

End: 2154971

Strand: Direct

Name: qorA [H]

Synonym: KP1_2237

Alternate gene names: 238894264

Gene position: 2153991-2154971 (Clockwise)

Preceding gene: 238894263

Following gene: 238894267

Centisome position: 41.04

GC content: 61.37

Gene sequence:

>981_bases
GTGAAATATATTGCTATCAGCCAACCGGGCGGCCCGGAGGTATTGCAGATCCGCGAAGGGGAGATCCCCACCATCGGGGA
GCATGAGGTGCTCATTGAGGTGAAGGCGGCGGGCGTCAACCGGCCGGATATTCTGCAGCGCCAGGGTCTGTATCCCATGC
CTGAGGGCGTCACCCCCGTGCCCGGCCTGGAGGTGGCGGGCGTGGTTGTTAAGGTCGGCGCGCAGGTCACAGCGTTTATG
CCCGGCGATCGCGTTTGCGCGCTGACCAACGGCGGCGGCTATGCCGAATACTGCGCCGTGCCGGCAGGCCAGACGTTGCC
GATCCCGGCGGGCCTCAGCTTTAGCGAAGCGGCCGCCATTCCGGAAACCTTCTTCACCGTCTGGGCGAACGTCTTCCAGC
TGGGTAAGCTGCAGCCTGGCGAAAGCATTCTGGTCCACGGCGGCGCCAGCGGGATTGGCACCACCGCGGTCCAGCTGTGC
CACGCGCTGGGGATGACCGTCTATGCCACCGTCGGCCAGGACGAAAAAATTGCTGCGCTACGTCCCTATGCTACGGCGAT
TAACTACAAAACAGATGATTTTGCCGAGAAAATCGGCCAGCTGACCAACGATGAAGGGGTGGACGTCATTCTGGATATTG
TTGGCGGCCCTTACTTTAACCGCAACCTTGGGCTACTGAAAAAGGATGGACGACTGGTCATCATCGGCTTTATGGGCGGG
CGAATCGCTCATGAGGTTGATATTCAGACTCTGATGCTCAAGCGAGCCACCGTCACCGGCTCGACCATGCGCGGCCGGAC
GGCGGCGGAGAAACAGCAGATTGCCGAGGCGCTGCGCCGCCACGTCTGGCCGCTGCTTGAGGCAGGGAAATGCAAGCCGC
TGATCTACGCCAGCTACCCGATGGCGGAGATTGCCGAGGCCCATGCCTGTCTGGACAGTGGTCAGCATCTGGGGAAAGTT
GTGATCACGATGACGTCGTGA

Upstream 100 bases:

>100_bases
CCGGGAAGAGCCTGGACGCGGGGCCCCTGAGCAGGGGATGCCCGCTGCGCTTTTCCTGATGCCGATGCCCCATTTCTCTC
ACAGGCGATAAGGAGGACCC

Downstream 100 bases:

>100_bases
GACGCATCCCGGCGGGCTGCCGCCGGGATGGAGTTAGGGGTGGTTAAATCACGCCCTGGGCCAGCATGGCATCCGCAACC
TTCACGAAACCGGCGATATT

Product: putative zinc-containing oxydoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKYIAISQPGGPEVLQIREGEIPTIGEHEVLIEVKAAGVNRPDILQRQGLYPMPEGVTPVPGLEVAGVVVKVGAQVTAFM
PGDRVCALTNGGGYAEYCAVPAGQTLPIPAGLSFSEAAAIPETFFTVWANVFQLGKLQPGESILVHGGASGIGTTAVQLC
HALGMTVYATVGQDEKIAALRPYATAINYKTDDFAEKIGQLTNDEGVDVILDIVGGPYFNRNLGLLKKDGRLVIIGFMGG
RIAHEVDIQTLMLKRATVTGSTMRGRTAAEKQQIAEALRRHVWPLLEAGKCKPLIYASYPMAEIAEAHACLDSGQHLGKV
VITMTS

Sequences:

>Translated_326_residues
MKYIAISQPGGPEVLQIREGEIPTIGEHEVLIEVKAAGVNRPDILQRQGLYPMPEGVTPVPGLEVAGVVVKVGAQVTAFM
PGDRVCALTNGGGYAEYCAVPAGQTLPIPAGLSFSEAAAIPETFFTVWANVFQLGKLQPGESILVHGGASGIGTTAVQLC
HALGMTVYATVGQDEKIAALRPYATAINYKTDDFAEKIGQLTNDEGVDVILDIVGGPYFNRNLGLLKKDGRLVIIGFMGG
RIAHEVDIQTLMLKRATVTGSTMRGRTAAEKQQIAEALRRHVWPLLEAGKCKPLIYASYPMAEIAEAHACLDSGQHLGKV
VITMTS
>Mature_326_residues
MKYIAISQPGGPEVLQIREGEIPTIGEHEVLIEVKAAGVNRPDILQRQGLYPMPEGVTPVPGLEVAGVVVKVGAQVTAFM
PGDRVCALTNGGGYAEYCAVPAGQTLPIPAGLSFSEAAAIPETFFTVWANVFQLGKLQPGESILVHGGASGIGTTAVQLC
HALGMTVYATVGQDEKIAALRPYATAINYKTDDFAEKIGQLTNDEGVDVILDIVGGPYFNRNLGLLKKDGRLVIIGFMGG
RIAHEVDIQTLMLKRATVTGSTMRGRTAAEKQQIAEALRRHVWPLLEAGKCKPLIYASYPMAEIAEAHACLDSGQHLGKV
VITMTS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=36.3636363636364, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=36.3636363636364, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=32.5227963525836, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=32.5227963525836, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI18379349, Length=326, Percent_Identity=31.5950920245399, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI194239676, Length=328, Percent_Identity=30.7926829268293, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI24308257, Length=237, Percent_Identity=32.9113924050633, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI197927207, Length=180, Percent_Identity=30.5555555555556, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI28557745, Length=226, Percent_Identity=32.7433628318584, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI41872631, Length=251, Percent_Identity=26.2948207171315, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI47519420, Length=370, Percent_Identity=26.7567567567568, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI90669511, Length=232, Percent_Identity=27.1551724137931, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1790485, Length=319, Percent_Identity=32.6018808777429, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788075, Length=332, Percent_Identity=23.1927710843373, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI226510992, Length=312, Percent_Identity=23.7179487179487, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081918, Length=326, Percent_Identity=26.6871165644172, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=310, Percent_Identity=27.741935483871, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI212642053, Length=310, Percent_Identity=24.8387096774194, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71987554, Length=172, Percent_Identity=30.2325581395349, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17556000, Length=276, Percent_Identity=26.4492753623188, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=330, Percent_Identity=28.7878787878788, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323961, Length=283, Percent_Identity=25.0883392226148, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581345, Length=252, Percent_Identity=27.3809523809524, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI221330659, Length=273, Percent_Identity=26.007326007326, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920632, Length=273, Percent_Identity=26.007326007326, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45550423, Length=182, Percent_Identity=30.2197802197802, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34618; Mature: 34618

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIAISQPGGPEVLQIREGEIPTIGEHEVLIEVKAAGVNRPDILQRQGLYPMPEGVTPV
CCEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGVVVKVGAQVTAFMPGDRVCALTNGGGYAEYCAVPAGQTLPIPAGLSFSEAAAI
CCCHHHHEEEEECCEEEEECCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHCC
PETFFTVWANVFQLGKLQPGESILVHGGASGIGTTAVQLCHALGMTVYATVGQDEKIAAL
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEE
RPYATAINYKTDDFAEKIGQLTNDEGVDVILDIVGGPYFNRNLGLLKKDGRLVIIGFMGG
CCHHEEECCCCHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCEEECCCCEEEEEECCC
RIAHEVDIQTLMLKRATVTGSTMRGRTAAEKQQIAEALRRHVWPLLEAGKCKPLIYASYP
CEEHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
MAEIAEAHACLDSGQHLGKVVITMTS
HHHHHHHHHHHHCCCCCCEEEEEEEC
>Mature Secondary Structure
MKYIAISQPGGPEVLQIREGEIPTIGEHEVLIEVKAAGVNRPDILQRQGLYPMPEGVTPV
CCEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGVVVKVGAQVTAFMPGDRVCALTNGGGYAEYCAVPAGQTLPIPAGLSFSEAAAI
CCCHHHHEEEEECCEEEEECCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHCC
PETFFTVWANVFQLGKLQPGESILVHGGASGIGTTAVQLCHALGMTVYATVGQDEKIAAL
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEE
RPYATAINYKTDDFAEKIGQLTNDEGVDVILDIVGGPYFNRNLGLLKKDGRLVIIGFMGG
CCHHEEECCCCHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCEEECCCCEEEEEECCC
RIAHEVDIQTLMLKRATVTGSTMRGRTAAEKQQIAEALRRHVWPLLEAGKCKPLIYASYP
CEEHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
MAEIAEAHACLDSGQHLGKVVITMTS
HHHHHHHHHHHHCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]